Product image of Lacosamide Fresenius Kabi (Lacosamide) supplied by GNH India

Lacosamide Fresenius Kabi

Active Ingredient:
Lacosamide
Origin:
EU

Lacosamide Fresenius Kabi (Lacosamide)

Lacosamide, the active ingredient in Lacosamide Fresenius Kabi, is an anticonvulsant presented as an injectable solution for intravenous use. It is indicated for the treatment of partial‑onset seizures in patients with epilepsy, helping to reduce seizure frequency and improve seizure control.\n\nGNH India supplies Lacosamide Fresenius Kabi as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Fresenius Kabi Deutschland Gmbh

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Lacosamide is an antiepileptic agent used in the management of seizure disorders.\n\nPartial‑onset seizures: reduces seizure frequency in patients with focal epilepsy.\nAdjunct therapy for refractory focal seizures: used as add‑on when seizures are not adequately controlled by other antiepileptic drugs.\nEpilepsy overall: contributes to overall seizure control as part of a comprehensive treatment regimen.

How It Works

  • Lacosamide enhances the slow inactivation of voltage‑gated sodium channels, which stabilizes hyperexcitable neuronal membranes and limits repetitive neuronal firing. By selectively targeting the slow inactivation phase, it reduces the propagation of abnormal electrical activity without markedly affecting normal neuronal conduction, thereby providing seizure‑preventing effects.

Side Effects

  • Lacosamide may cause a range of adverse reactions, which vary in frequency and severity.\n\nCommon Side Effects:\n- Nausea: mild to moderate gastrointestinal upset.\n- Dizziness: transient sensation of light‑headedness.\n- Headache: mild to moderate pain in the head region.\n- Somnolence: increased sleepiness or fatigue.\n- Blurred vision: temporary visual disturbances.\n- Fatigue: general feeling of tiredness.\n\nSerious or Rare Side Effects:\n- Cardiac arrhythmias: irregular heart rhythms, including PR‑interval prolongation.\n- Suicidal ideation: thoughts of self‑harm requiring immediate assessment.\n- Severe skin reactions: such as Stevens‑Johnson syndrome or toxic epidermal necrolysis.\n- Respiratory depression: reduced breathing effort, especially when combined with other depressants.\n- Anaphylaxis: rare but potentially life‑threatening allergic reaction.

Precautions & Warnings

  • When using Lacosamide, clinicians should consider several safety measures to minimize risk.\n\nMonitor cardiac function: observe for PR‑interval changes and arrhythmias.\nAdjust dose in renal impairment: reduce dosage in patients with decreased kidney function.\nAvoid abrupt discontinuation: taper gradually to prevent seizure recurrence.\nUse caution in hepatic disease: monitor liver enzymes and adjust dosing if needed.\nAssess for psychiatric symptoms: watch for mood changes or suicidal thoughts.\nStore at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

  • Lacosamide can interact with other medicines, affecting its efficacy or safety.\n\nMajor Interactions (Avoid):\n- Carbamazepine: may reduce lacosamide plasma levels.\n- Phenytoin: can lower lacosamide concentrations.\n- Strong CYP3A4 inhibitors (e.g., ketoconazole): increase lacosamide exposure.\n\nModerate Interactions (Monitor Closely):\n- Other antiepileptics (e.g., valproate): may require dose adjustments.\n- Serotonergic agents (e.g., SSRIs): monitor for serotonin syndrome.\n- Antihypertensives: observe for additive blood pressure effects.

Frequently Asked Questions

Lacosamide Fresenius Kabi is an injectable antiepileptic medication indicated for the treatment of partial‑onset seizures in patients with epilepsy. It helps reduce the frequency of focal seizures and is often used as part of a broader seizure‑control regimen.

Lacosamide enhances the slow inactivation of voltage‑gated sodium channels in neuronal membranes. This stabilizes hyper‑excitable neurons, limits repetitive firing, and thereby reduces the propagation of abnormal electrical activity that can trigger seizures.

The dosage of Lacosamide is individualized and determined by the prescribing clinician based on the patient’s condition, response, and renal function. Healthcare professionals set the appropriate dose and infusion rate according to clinical guidelines.

Safety data for Lacosamide in pregnancy and lactation are limited. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and the decision should be made by a qualified healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed), and import documentation.

Lacosamide’s unique mechanism—enhancing slow sodium‑channel inactivation—differs from many traditional antiepileptics that target fast inactivation. This can provide additive seizure control when combined with other agents, and it may have a more favorable side‑effect profile for certain patients compared with older sodium‑channel blockers.

Lacosamide injectable solution should be stored at 2‑8 °C, protected from light, and must not be frozen or shaken. Keep the product in its original packaging until use to maintain stability and potency.

Lacosamide Fresenius Kabi is administered intravenously. It can be given as a slow infusion over several minutes or as a continuous infusion, depending on the clinical setting and physician’s instructions.

Serious risks include cardiac arrhythmias such as PR‑interval prolongation, severe skin reactions like Stevens‑Johnson syndrome, respiratory depression, and the potential for suicidal thoughts or behavior. Prompt medical attention is required if any of these events occur.

Lacosamide is contraindicated in patients with known hypersensitivity to the drug or any of its excipients. Caution is also advised for individuals with significant cardiac conduction abnormalities, severe renal impairment, or uncontrolled psychiatric conditions.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.