Product image of Lacosamide Fresenius Kabi (Lacosamide) supplied by GNH India

Lacosamide Fresenius Kabi

Active Ingredient:
Lacosamide
Origin:
EU

Lacosamide Fresenius Kabi (Lacosamide)

Lacosamide, the active ingredient in Lacosamide Fresenius Kabi, is a sodium channel blocker presented as an injectable solution for intravenous use. It is used as adjunctive therapy for partial‑onset seizures in patients with epilepsy.

GNH India supplies Lacosamide Fresenius Kabi as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

Manufacturer / TM Owner

Fresenius Kabi Norge As

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Lacosamide is an antiepileptic drug that acts on neuronal sodium channels to control seizure activity.

  • Partial‑onset seizures: reduces seizure frequency when added to existing therapy.
  • Focal epilepsy: helps achieve better seizure control in patients with refractory focal seizures.
  • Adjunctive therapy for epilepsy: improves overall seizure management when combined with other antiepileptic medications.

How It Works

  • Lacosamide enhances the slow inactivation of voltage‑gated sodium channels, stabilizing hyperexcitable neuronal membranes and diminishing repetitive neuronal firing. This modulation reduces the propagation of epileptic discharges, thereby decreasing seizure occurrence without significantly affecting normal neuronal activity.

Side Effects

Lacosamide may cause a range of adverse reactions, which vary in frequency and severity.

Common Side Effects

  • Dizziness: sensation of light‑headedness or unsteadiness.
  • Nausea: feeling of stomach upset or urge to vomit.
  • Headache: mild to moderate cranial pain.
  • Fatigue: increased tiredness or lack of energy.
  • Blurred vision: temporary visual disturbances.
  • Diplopia: double vision.

Serious or Rare Side Effects

  • Cardiac arrhythmia: irregular heart rhythm, including atrial fibrillation.
  • Severe skin reactions: such as Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Suicidal ideation: thoughts of self‑harm or suicide.
  • Respiratory depression: slowed breathing requiring monitoring.
  • Anaphylaxis: severe allergic reaction with potential airway compromise.
  • Hepatotoxicity: liver enzyme elevations indicating possible liver injury.

Precautions & Warnings

When prescribing Lacosamide, clinicians should consider several safety aspects.

  • Renal impairment: assess kidney function and adjust dose if necessary.
  • Hepatic impairment: monitor liver enzymes and consider dose modification.
  • Cardiac conduction: obtain baseline ECG and monitor for arrhythmias.
  • Concomitant antiepileptics: watch for additive CNS depression.
  • Pregnancy: safety data are limited; use only if benefit outweighs potential risk.
  • Store at room temperature: keep in original packaging, protect from moisture and light.

Avoid Interactions

Lacosamide can interact with other medicines, affecting efficacy or safety.

Major Interactions (Avoid)

  • Strong CYP3A4 inducers (e.g., carbamazepine): may markedly reduce lacosamide levels.
  • Other sodium channel blockers: increase risk of central nervous system depression.
  • QT‑prolonging agents: may heighten the chance of cardiac arrhythmias.

Moderate Interactions (Monitor Closely)

  • Oral contraceptives: lacosamide may decrease hormonal efficacy.
  • Valproate: may require dose adjustments due to altered plasma concentrations.
  • Alcohol: concurrent use can intensify dizziness and sedation.

Frequently Asked Questions

Lacosamide Fresenius Kabi is an injectable antiepileptic medication used as adjunctive therapy for partial‑onset seizures and focal epilepsy. It is administered intravenously in hospital settings to help patients achieve better seizure control when other treatments are insufficient.

Lacosamide enhances the slow inactivation of voltage‑gated sodium channels in neurons. By stabilizing hyperexcitable neuronal membranes, it reduces repetitive firing and the spread of epileptic activity, thereby decreasing the frequency and severity of seizures.

The specific dose of Lacosamide Fresenius Kabi is determined by the prescribing clinician based on the patient’s clinical condition, age, weight, renal and hepatic function, and concomitant medications. Dosage regimens are individualized and should follow the prescriber’s instructions.

Safety data for lacosamide in pregnancy and lactation are limited. It should only be used if the potential benefit to the mother outweighs any possible risk to the fetus or infant. Women who are pregnant, planning pregnancy, or breastfeeding should discuss risks with their healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed), and necessary import documentation.

Lacosamide is distinct for its selective enhancement of slow sodium channel inactivation, offering a different mechanism compared with traditional sodium channel blockers like carbamazepine. It is often chosen for patients who have not achieved adequate seizure control with other agents, and it has a relatively favorable interaction profile.

Lacosamide Fresenius Kabi should be stored at room temperature, below 25 °C, in its original packaging. Protect the vials from moisture and direct light. Do not freeze. Inspect the solution for particulate matter or discoloration before administration.

The product is supplied as an injectable solution for intravenous infusion. Administration is performed by qualified healthcare professionals in a clinical setting, following aseptic technique and the dosing instructions provided by the prescriber.

Serious risks include cardiac arrhythmias such as atrial fibrillation, severe skin reactions like Stevens‑Johnson syndrome, suicidal thoughts or behaviors, respiratory depression, and rare cases of anaphylaxis. Patients should be monitored for these events, especially during treatment initiation or dose changes.

Lacosamide is contraindicated in patients with known hypersensitivity to the drug or any of its excipients. Caution is also advised for individuals with significant cardiac conduction disorders, uncontrolled arrhythmias, or severe renal or hepatic impairment unless dose adjustments are made.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.