Product image of Lacosamide Sandoz (Lacosamide) supplied by GNH India

Lacosamide Sandoz

Active Ingredient:
Lacosamide
Origin:
EU

Lacosamide Sandoz (Lacosamide)

Lacosamide, the active ingredient in Lacosamide Sandoz, is a sodium channel blocker presented as an oral tablet for oral use. It is indicated as adjunctive treatment of partial‑onset seizures in adults.
GNH India supplies Lacosamide Sandoz as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Sandoz

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Lacosamide is an anticonvulsant used in the management of seizure disorders.
  • Partial‑onset seizures: Used as adjunctive therapy to reduce seizure frequency in patients with focal epilepsy.
  • Focal epilepsy: Enhances seizure control when added to existing antiepileptic regimens.
  • Refractory focal seizures: Provides an additional therapeutic option for patients not adequately controlled by other medications.

How It Works

  • Lacosamide selectively enhances the slow inactivation of voltage‑gated sodium channels in neuronal membranes. By stabilizing the inactive state of these channels, it reduces repetitive neuronal firing and diminishes hyper‑excitability that underlies seizure activity, without significantly affecting normal neuronal conduction.

Side Effects

Lacosamide may cause a range of adverse reactions, from mild to serious.

Common Side Effects

  • Dizziness
  • Headache
  • Nausea
  • Fatigue
  • Diplopia (double vision)
  • Somnolence

Serious or Rare Side Effects

  • Cardiac arrhythmias (including PR‑interval prolongation)
  • Suicidal thoughts or behavior
  • Severe skin reactions such as Stevens‑Johnson syndrome
  • Hypersensitivity reactions (rash, angioedema)
  • Hepatic injury
  • Rhabdomyolysis

Precautions & Warnings

When prescribing Lacosamide, clinicians should consider several safety aspects.

  • Renal impairment: Adjust dose or monitor renal function closely.
  • Hepatic impairment: Monitor liver enzymes and consider dose modification.
  • Cardiac conduction disorders: Perform ECG monitoring in patients with known arrhythmias.
  • Pregnancy: Safety not established; weigh potential benefits against risks.
  • Concomitant CNS depressants: May increase sedation; observe patient response.
  • Store at ambient temperature: Keep in original container, protect from moisture and light.

Avoid Interactions

Lacosamide can interact with other medicines, affecting its efficacy or safety.

Major Interactions (Avoid)

  • Carbamazepine: Decreases lacosamide plasma concentrations.
  • Phenytoin: Reduces lacosamide exposure.
  • Rifampin: Lowers lacosamide levels significantly.

Moderate Interactions (Monitor Closely)

  • CNS depressants (e.g., benzodiazepines, opioids): May enhance sedation.
  • Alcohol: Can increase dizziness and drowsiness.
  • Other antiepileptic drugs: May require therapeutic drug monitoring.

Frequently Asked Questions

Lacosamide Sandoz is prescribed as an adjunctive therapy for partial‑onset (focal) seizures in adults with epilepsy. It is added to existing antiepileptic regimens to help reduce the frequency of seizure episodes when monotherapy is insufficient.

Lacosamide enhances the slow inactivation of voltage‑gated sodium channels in neurons. This stabilizes the inactive state of the channels, limiting repetitive firing and decreasing neuronal hyper‑excitability that contributes to seizure generation.

The specific dose of Lacosamide Sandoz is determined by the prescribing clinician based on the patient’s clinical condition, response, and tolerability. Dosage adjustments may be needed for renal or hepatic impairment, and the prescriber will provide individualized instructions.

Safety data for lacosamide in pregnancy and lactation are limited, and the pregnancy category is listed as unknown. Clinicians should evaluate the potential benefits against possible risks before prescribing to pregnant or nursing women.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Lacosamide belongs to the sodium channel blocker class, offering a distinct mechanism that enhances slow inactivation of sodium channels. Compared with drugs that target fast inactivation (e.g., carbamazepine), lacosamide may have a different side‑effect profile and can be useful when other agents are ineffective or not tolerated.

Lacosamide Sandoz tablets should be stored at ambient temperature, below 25 °C, in the original packaging to protect from moisture and light. Keep the product out of reach of children and do not use if the packaging is damaged.

Lacosamide Sandoz is taken orally, usually as a tablet, with or without food. The exact administration schedule is set by the prescriber, who may recommend taking the dose at the same time each day to maintain consistent blood levels.

Serious risks include cardiac conduction abnormalities such as PR‑interval prolongation, potential suicidal thoughts or behaviors, severe skin reactions like Stevens‑Johnson syndrome, hypersensitivity reactions, hepatic injury, and rare cases of rhabdomyolysis. Patients should be monitored for these events, especially during treatment initiation.

Lacosamide Sandoz is contraindicated in patients with known hypersensitivity to lacosamide or any of its excipients. Caution is advised for individuals with significant cardiac conduction disorders, severe hepatic impairment, or those taking interacting medications that could markedly reduce its effectiveness.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.