Product image of Lacosamide Teva (Lacosamide) supplied by GNH India

Lacosamide Teva

Active Ingredient:
Lacosamide
Origin:
EU

Lacosamide Teva (Lacosamide)

Lacosamide, the active ingredient in Lacosamide Teva, is a sodium channel blocker presented as an oral tablet for oral use. It is indicated for the treatment of partial‑onset seizures, either as adjunctive therapy or as monotherapy in patients with focal onset epilepsy.

GNH India supplies Lacosamide Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with distribution across the European Union and other regulated markets. The company adheres to stringent quality standards and provides comprehensive regulatory support for importers.

Manufacturer / TM Owner

Teva Nederland B.V.

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Indications & Clinical Uses

Lacosamide is an antiepileptic drug that modulates neuronal excitability in seizure disorders.

  • Partial‑onset seizures (adjunctive therapy): reduces seizure frequency when added to existing antiepileptic regimens.
  • Focal onset seizures (monotherapy): provides seizure control as the sole antiepileptic agent.

How It Works

  • Lacosamide selectively enhances the slow inactivation of voltage‑gated sodium channels in neuronal membranes. By stabilizing the inactive state of these channels, it diminishes repetitive neuronal firing and reduces hyper‑excitability that underlies epileptic seizures. This mechanism contributes to its efficacy in both adjunctive and monotherapy settings for focal epilepsies.

Side Effects

Lacosamide may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects

  • Dizziness: sensation of light‑headedness or imbalance.
  • Fatigue: feeling unusually tired or weak.
  • Nausea: upset stomach often accompanied by the urge to vomit.

Serious or Rare Side Effects

  • Cardiac arrhythmia: irregular heart rhythm, including PR‑interval prolongation.
  • Severe skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Rhabdomyolysis: muscle breakdown with elevated creatine kinase levels.

Precautions & Warnings

When prescribing Lacosamide, clinicians should consider several precautionary measures to ensure safe use.

  • Renal impairment: dose may need adjustment and renal function should be monitored.
  • Hepatic impairment: use with caution; monitor liver enzymes regularly.
  • Cardiac conduction

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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