Product image of Lacosamide Teva (Lacosamide) supplied by GNH India

Lacosamide Teva

Active Ingredient:
Lacosamide
Origin:
EU

Lacosamide Teva (Lacosamide)

Lacosamide, the active ingredient in Lacosamide Teva, is an anti‑epileptic (sodium channel modulator) presented as an oral tablet for oral use. It treats partial‑onset (focal) seizures as adjunctive therapy in patients with epilepsy.

GNH India supplies Lacosamide Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Teva B.V

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Indications & Clinical Uses

Lacosamide is an anti‑epileptic drug used to manage focal seizure disorders and related epilepsy conditions.

  • Partial‑onset (focal) seizures: adjunctive reduction of seizure frequency.
  • Focal epilepsy: improves seizure control when combined with other antiepileptics.
  • Refractory epilepsy: provides additional seizure protection as part of combination therapy.

How It Works

  • Lacosamide enhances the slow inactivation of voltage‑gated sodium channels, stabilizing neuronal membranes and reducing hyperexcitability. It also binds to collapsin response mediator protein‑2 (CRMP2), which modulates axonal growth and neurotransmitter release, contributing to its anticonvulsant effect without affecting normal neuronal firing.

Side Effects

Lacosamide may cause a range of adverse reactions, from mild to serious.

Common Side Effects

  • Dizziness
  • Nausea
  • Headache
  • Fatigue

Serious or Rare Side Effects

  • Cardiac conduction abnormalities such as PR‑interval prolongation
  • Severe skin reactions, including Stevens‑Johnson syndrome
  • Suicidal ideation or behavior

Precautions & Warnings

When prescribing Lacosamide, clinicians should consider several safety measures.

  • Cardiac monitoring: obtain baseline ECG and repeat if symptoms arise.
  • Renal function assessment: adjust dosing in severe impairment.
  • Concomitant antiepileptic review: avoid abrupt changes in therapy.
  • Patient counseling: advise caution when driving or operating machinery due to dizziness.
  • Store at ambient temperature: keep below 25 °C, retain in original packaging, protect from moisture.

Avoid Interactions

Lacosamide can interact with other medicines, requiring attention to avoid reduced efficacy or increased toxicity.

Major Interactions (Avoid)

  • Strong CYP3A4 inducers (e.g., carbamazepine, phenytoin, phenobarbital) may lower lacosamide levels.
  • Co‑administration with other sodium‑channel blockers can increase CNS depression.
  • Drugs that prolong PR interval (e.g., certain antiarrhythmics) may exacerbate cardiac effects.

Moderate Interactions (Monitor Closely)

  • Combination with other antiepileptics may require dose adjustments.
  • Oral contraceptives may become less effective; consider alternative contraception.
  • Alcohol use can enhance dizziness and sedation.

Frequently Asked Questions

Lacosamide Teva is prescribed as an adjunctive treatment for partial‑onset (focal) seizures in patients with epilepsy. It helps reduce the frequency of seizures when added to other antiepileptic medications.

Lacosamide enhances the slow inactivation of voltage‑gated sodium channels, stabilizing neuronal membranes and decreasing hyperexcitability. It also binds to CRMP2, influencing neuronal signaling pathways that contribute to seizure control.

The specific dose of Lacosamide Teva is determined by the prescribing clinician based on the individual’s medical condition, response to therapy, and other medications. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety data for lacosamide in pregnancy and lactation are limited. Healthcare providers should weigh the potential benefits against possible risks and discuss alternative options when appropriate.

To request Lacosamide Teva, submit an enquiry on the product page at gnhindia.com indicating the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, confirming trade or institutional credentials before providing pricing, availability, shipping details, and necessary import documentation.

Lacosamide’s unique mechanism—enhancing slow sodium‑channel inactivation—differs from many traditional antiepileptics that target fast inactivation. This can provide complementary seizure control when combined with other agents, often with a distinct side‑effect profile.

Lacosamide Teva tablets should be stored at ambient temperature, below 25 °C, in their original packaging. Protect them from moisture and direct sunlight to maintain stability.

The medication is taken orally as a tablet, usually with or without food. Patients should swallow the tablet whole and follow the dosing schedule prescribed by their healthcare professional.

Serious risks include cardiac conduction abnormalities such as PR‑interval prolongation, severe skin reactions like Stevens‑Johnson syndrome, and the potential for suicidal thoughts or behavior. Prompt medical attention is required if any of these occur.

Patients with known hypersensitivity to lacosamide or any tablet excipients should avoid the product. Those with significant cardiac conduction disorders or uncontrolled arrhythmias should be evaluated carefully before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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