Product image of Lacosamide Treatment Initiation Pack (In Adolescent And Children Weighing 50 Kg Or More And Adults O (Lacosamide) supplied by GNH India

Lacosamide Treatment Initiation Pack (In Adolescent And Children Weighing 50 Kg Or More And Adults O

Active Ingredient:
Lacosamide
Origin:
EU

Lacosamide Treatment Initiation Pack (In Adolescent And Children Weighing 50 Kg Or More And Adults O (Lacosamide)

Lacosamide, the active ingredient in Lacosamide Treatment Initiation Pack (In Adolescent And Children Weighing 50 Kg Or More And Adults O), is a sodium channel blocker presented as an oral formulation for oral use. It is indicated for the management of partial‑onset seizures in adolescents, children weighing ≥50 kg, and adults.

GNH India supplies Lacosamide Treatment Initiation Pack as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory documentation for global distribution.

Manufacturer / TM Owner

Accord Healthcare S.L.U.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Lacosamide is an anticonvulsant that acts on voltage‑gated sodium channels to control seizure activity.

  • Partial‑onset seizures: reduces seizure frequency as adjunct therapy.
  • Focal epilepsy: improves seizure control when added to existing regimens.
  • Refractory epilepsy: offers an alternative mechanism for patients not responding to other agents.

How It Works

  • Lacosamide enhances the slow inactivation of voltage‑gated sodium channels in neuronal membranes, stabilizing hyper‑excitable neuronal membranes and decreasing repetitive firing. By selectively targeting the slow inactivation phase, it reduces neuronal hyperexcitability without markedly affecting normal conduction, thereby diminishing the propagation of epileptic discharges.

Side Effects

Lacosamide may cause a range of adverse reactions, which are categorized by frequency.

Common Side Effects

  • Dizziness: transient sensation of light‑headedness.
  • Nausea: mild to moderate stomach upset.
  • Headache: occasional tension‑type pain.
  • Fatigue: feeling of reduced energy.

Serious or Rare Side Effects

  • Cardiac arrhythmia: alterations in heart rhythm, especially PR‑interval prolongation.
  • Suicidal ideation: emergence of depressive thoughts or behaviors.
  • Severe skin reactions: such as Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Hypersensitivity: including anaphylaxis or angioedema.

Precautions & Warnings

Before initiating therapy, clinicians should consider several safety measures.

  • Dose titration: increase gradually as directed by the prescriber to minimize neurologic effects.
  • Cardiac monitoring: obtain baseline ECG and monitor PR interval in patients with cardiac disease.
  • Renal function: adjust dosing in severe renal impairment.
  • Pregnancy: avoid use unless the potential benefit justifies the potential risk to the fetus.
  • Store at ambient temperature: keep below 25 °C, retain in original packaging, and protect from moisture.

Avoid Interactions

Lacosamide can interact with other medicines, influencing efficacy or safety.

Major Interactions (Avoid)

  • Strong CYP3A4 inducers (e.g., carbamazepine, phenytoin): may markedly reduce lacosamide plasma concentrations.
  • Concurrent sodium‑channel blockers (e.g., lamotrigine, carbamazepine): increase risk of additive central nervous system depression.

Moderate Interactions (Monitor Closely)

  • Oral contraceptives: lacosamide may decrease hormonal effectiveness; advise alternative contraception.
  • Drugs that prolong PR interval (e.g., diltiazem, verapamil): monitor ECG for further PR‑interval changes.

Frequently Asked Questions

Lacosamide Treatment Initiation Pack is used as an adjunctive therapy for the control of partial‑onset seizures in adolescents, children who weigh at least 50 kg, and adults. It belongs to the sodium channel blocker class of anticonvulsants and helps reduce the frequency of seizure episodes when added to existing antiepileptic regimens.

Lacosamide works by enhancing the slow inactivation of voltage‑gated sodium channels in neuronal membranes. This action stabilizes hyper‑excitable neurons, limits repetitive firing, and thereby reduces the propagation of epileptic discharges without significantly affecting normal neuronal conduction.

The specific dose of lacosamide is determined by the treating physician based on the patient’s age, weight, renal function, and clinical response. Prescribers start with a low dose and titrate upward as needed, following established clinical guidelines and individual patient tolerance.

The safety of lacosamide in pregnancy and lactation has not been fully established. It should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant. Women who are pregnant, planning pregnancy, or breastfeeding should discuss alternatives and monitoring strategies with their healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request verification of trade or institutional credentials. After confirmation, the team provides pricing, availability, shipping details (including any cold‑chain requirements) and assists with import documentation.

Lacosamide offers a distinct mechanism by enhancing slow sodium‑channel inactivation, which differs from many traditional agents that target fast inactivation. This can provide additional seizure control for patients who have not responded adequately to other drugs. Its side‑effect profile is generally mild, but clinicians must consider cardiac and psychiatric risks that may be less prominent with some alternatives.

Lacosamide Treatment Initiation Pack should be stored at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain stability throughout its shelf life.

Lacosamide is administered orally, typically as tablets or an oral solution, and should be taken with or without food according to the prescriber’s instructions. The medication is swallowed whole with a glass of water and dosing intervals are maintained consistently to achieve stable plasma concentrations.

The most serious risks include cardiac arrhythmias such as PR‑interval prolongation, severe skin reactions like Stevens‑Johnson syndrome, and psychiatric effects including suicidal thoughts or behavior. Patients should be monitored for any new cardiac symptoms, skin changes, or mood alterations, and seek immediate medical attention if such events occur.

Lacosamide is contraindicated in individuals with known hypersensitivity to the drug or any of its excipients. Caution is also advised for patients with pre‑existing cardiac conduction disorders, severe renal impairment, or those taking strong CYP3A4 inducers that could markedly reduce drug exposure.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.