Product image of Lacrinorm (Carbomer) supplied by GNH India

Lacrinorm

Active Ingredient:
Carbomer
Origin:
EU

Lacrinorm (Carbomer)

Carbomer, the active ingredient in Lacrinorm, is an ophthalmic excipient presented as a gel matrix for ocular use. It acts as a viscosity enhancer, forming a gel that increases the residence time of eye drops, thereby improving drug delivery for patients requiring sustained ocular therapy.

GNH India supplies Lacrinorm as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory‑compliant products to a global network of healthcare providers.

Manufacturer / TM Owner

Laboratoire Chauvin

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Indications & Clinical Uses

Lacrinorm, containing carbomer, is employed as a viscosity enhancer in ophthalmic formulations.

  • Ocular lubrication: prolongs tear film stability and enhances comfort in dry eye patients.
  • Post‑operative eye care: maintains therapeutic drug levels on the ocular surface after surgery.
  • Chronic ocular disease therapy: improves residence time of active agents in glaucoma or allergy eye drops.

How It Works

  • Carbomer is a high‑molecular‑weight polymer that swells in aqueous media to form a cross‑linked gel matrix. This matrix increases the viscosity of ophthalmic solutions, slowing tear‑film turnover and prolonging the contact time of the active drug on the ocular surface, thereby enhancing its therapeutic effect.

Side Effects

Adverse reactions may occur with ocular administration of carbomer‑based products.

Common Side Effects

  • Transient ocular irritation: mild stinging or burning upon instillation.
  • Temporary blurred vision: visual disturbance that resolves within minutes.
  • Mild conjunctival redness: slight redness without pain.

Serious or Rare Side Effects

  • Allergic reaction: swelling, itching, or rash requiring discontinuation.
  • Corneal edema: swelling of the cornea leading to vision changes.
  • Severe ocular inflammation: uveitis or keratitis requiring medical attention.

Precautions & Warnings

When using Lacrinorm, consider the following precautions:

  • Patient assessment: evaluate ocular surface condition before use.
  • Allergy screening: check for known carbomer sensitivity.
  • Concurrent eye medications: avoid mixing with incompatible formulations.
  • Contact lens wearers: remove lenses before instillation.
  • Pregnancy and lactation: use only if benefits outweigh potential risks.
  • Store at room temperature: keep in the original container, protect from moisture and direct light.

Avoid Interactions

Potential interactions with other ophthalmic products should be monitored.

Major Interactions (Avoid)

  • Incompatible ophthalmic gels: co‑administration may alter viscosity and drug release.
  • Preservative‑containing drops: may cause precipitation of the gel matrix.

Moderate Interactions (Monitor Closely)

  • Contact lens solutions: may affect gel stability.
  • Topical antibiotics: monitor for reduced efficacy.
  • Systemic medications: generally none, but observe for unexpected ocular effects.

Frequently Asked Questions

Lacrinorm is an ophthalmic excipient that contains carbomer, a polymer used to increase the viscosity of eye drop formulations. By forming a gel matrix, it prolongs the residence time of the active drug on the ocular surface, improving therapeutic efficacy in conditions such as dry eye, post‑surgical care, and chronic eye diseases.

Carbomer is a high‑molecular‑weight polymer that swells when hydrated, creating a cross‑linked gel. This gel increases the thickness of the eye drop solution, slowing its clearance by tears and enhancing the contact time of the active ingredient with the eye, which can lead to better drug absorption and effect.

The dosage of Lacrinorm is determined by the prescribing ophthalmologist or pharmacist based on the specific eye drop formulation and the patient’s condition. The prescriber sets the appropriate volume and frequency of administration, and no standard dose can be provided without a professional recommendation.

Safety data for carbomer in pregnant or nursing individuals are limited. Lacrinorm should only be used if the potential benefit justifies any potential risk to the mother or infant. Healthcare providers should evaluate the risk‑benefit profile before prescribing it to pregnant or lactating patients.

To order Lacrinorm, visit the product page on gnhindia.com and submit an enquiry with the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide. After the enquiry, the sales team will request trade or institutional credentials, then provide pricing, availability, shipping details (including any cold‑chain requirements), and import documentation.

Lacrinorm uses carbomer, which is widely recognized for its high viscosity and gel‑forming properties. Compared with alternatives such as hyaluronic acid or cellulose derivatives, carbomer typically offers a more robust gel matrix and longer residence time, though the choice depends on formulation requirements, patient tolerance, and specific therapeutic goals.

Lacrinorm should be stored at room temperature, preferably below 25 °C. Keep the product in its original container, protect it from moisture, direct sunlight, and extreme temperatures. Ensure the container is tightly closed to maintain the integrity of the gel matrix.

Lacrinorm is administered ocularly as part of an eye drop formulation. The prescribed number of drops is instilled onto the conjunctival sac of the eye, typically using a sterile dropper. Patients should follow the dosing instructions provided by their eye care professional.

The most serious risks involve hypersensitivity reactions, such as severe eye irritation, swelling, or allergic responses that may require discontinuation of the product. In rare cases, corneal edema or significant ocular inflammation can occur, necessitating immediate medical evaluation.

Individuals with a known allergy or hypersensitivity to carbomer or any component of the formulation should avoid using Lacrinorm. Patients with active severe ocular infections or uncontrolled inflammatory eye conditions should consult their ophthalmologist before use, as the gel may interfere with treatment.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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