Product image of Lacryvisc (Carbomer 974p) supplied by GNH India

Lacryvisc

Active Ingredient:
Carbomer 974p
Origin:
EU

Lacryvisc (Carbomer 974p)

Carbomer 974p, the active ingredient in Lacryvisc, is an excipient presented as a polymer in ophthalmic solutions for ocular use. It enhances the viscosity of eye drops to improve drug residence time on the ocular surface.

GNH India supplies Lacryvisc as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Alcon Portugal – Produtos E Equipamentos Oftalmológicos, Lda

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Indications & Clinical Uses

Lacryvisc is a viscosity‑enhancing excipient used in ophthalmic formulations to improve drug retention on the eye surface.

  • Dry Eye Syndrome: improves tear film stability and prolongs ocular surface hydration.
  • Post‑surgical eye drops: prolongs drug contact time, supporting healing after ocular surgery.
  • Ocular inflammation treatments: enhances ocular drug retention, aiding anti‑inflammatory efficacy.

How It Works

  • Carbomer 974p is a high‑molecular‑weight cross‑linked acrylic acid polymer that swells upon contact with aqueous media, forming a gel matrix. This increases the viscosity of ophthalmic solutions, slowing tear turnover and enhancing the residence time of active agents on the ocular surface without interacting with ocular receptors.

Side Effects

Lacryvisc may cause ocular reactions, most of which are mild and transient.

Common Side Effects

  • Transient blurred vision: temporary visual disturbance after instillation.
  • Mild ocular irritation: slight stinging or burning sensation.
  • Temporary tearing: increased tear production that resolves quickly.

Serious or Rare Side Effects

  • Allergic conjunctivitis: redness, swelling, and itching requiring discontinuation.
  • Corneal edema: swelling of the cornea, a rare but serious event.
  • Severe ocular inflammation: intense redness and pain indicating an adverse reaction.

Precautions & Warnings

When using Lacryvisc, consider the following precautions to ensure safety and product integrity.

  • Assess patient history: verify no known hypersensitivity to carbomer polymers.
  • Avoid use on compromised corneal epithelium: may exacerbate irritation.
  • Monitor for ocular discomfort: discontinue if severe irritation occurs.
  • Do not combine with incompatible preservatives: may affect formulation stability.
  • Store at ambient temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Lacryvisc can interact with certain ophthalmic components, affecting formulation stability or ocular tolerance.

Major Interactions (Avoid)

  • Incompatible preservatives: may cause precipitation or loss of viscosity.
  • Strong acids or bases: can degrade the polymer structure.

Moderate Interactions (Monitor Closely)

  • Other ophthalmic gels: may alter overall viscosity profile.
  • Contact lens solutions: could affect lens comfort or adherence.
  • Systemic anti‑inflammatory eye drops: may modify the ocular environment, requiring observation.

Frequently Asked Questions

Lacryvisc is used as a viscosity‑enhancing excipient in ophthalmic formulations. It helps thicken eye drops, allowing the active drug to remain longer on the ocular surface, which can improve therapeutic effectiveness.

Carbomer 974p is a high‑molecular‑weight polymer that swells in water to form a gel. This gel increases the viscosity of the eye drop, slowing tear turnover and extending the contact time of the active ingredient with the eye.

The dose of Lacryvisc is determined by the prescribing ophthalmologist based on the specific eye drop formulation and the patient’s needs. The prescriber sets the appropriate concentration and volume for each product.

Safety data for Carbomer 974p in pregnancy or lactation are limited. Use should be considered only if the potential benefit justifies any potential risk, and it is advisable to consult a healthcare professional before use.

To order Lacryvisc, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details and import documentation.

Lacryvisc, containing Carbomer 974p, offers high viscosity at low concentrations and is compatible with many ophthalmic actives. Compared with alternatives like hyaluronic acid or hydroxypropyl methylcellulose, Carbomer provides a stable gel matrix with predictable rheological properties.

Store Lacryvisc at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and avoid exposing it to extreme temperatures.

Lacryvisc is incorporated into ophthalmic solutions that are instilled as eye drops. The product is applied directly to the ocular surface according to the prescribing ophthalmologist’s instructions.

Serious risks, though rare, include allergic conjunctivitis, corneal edema, and severe ocular inflammation. Patients should discontinue use and seek medical attention if they experience significant redness, swelling, pain, or vision changes.

Individuals with a known hypersensitivity to Carbomer 974p or any component of the formulation should avoid using Lacryvisc. It is also contraindicated in eyes with active severe infection or compromised corneal integrity.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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