Product image of Lactulose Aiwa Pflaumenaroma T&d Pharma (Lactulose) supplied by GNH India

Lactulose Aiwa Pflaumenaroma T&d Pharma

Active Ingredient:
Lactulose
Origin:
EU

Lactulose Aiwa Pflaumenaroma T&d Pharma (Lactulose)

Lactulose, the active ingredient in Lactulose Aiwa Pflaumenaroma T&d Pharma, is an osmotic laxative presented as an oral solution for oral use. It is employed to relieve chronic constipation and to lower blood ammonia levels in patients with hepatic encephalopathy, improving bowel regularity and neurological status.

GNH India supplies Lactulose Aiwa Pflaumenaroma T&d Pharma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable logistics for global distribution.

Manufacturer / TM Owner

T&d Pharma Gmbh

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Lactulose is an osmotic laxative used to manage conditions related to impaired bowel motility and hepatic ammonia accumulation.

  • Constipation: relieves chronic constipation by increasing colonic water content and softening stools, promoting regular bowel movements.
  • Hepatic encephalopathy: lowers blood ammonia concentrations, helping improve mental status in patients with liver disease.
  • Opioid‑induced constipation: counteracts opioid‑related reduced gut motility, providing symptomatic relief in patients receiving chronic opioid therapy.

How It Works

  • After oral ingestion, lactulose reaches the colon where resident bacteria hydrolyze it into lactic acid and acetic acid. The resulting short‑chain fatty acids lower colonic pH and create an osmotic gradient that draws water into the lumen, softening the stool and stimulating peristalsis. In hepatic encephalopathy, the acidic environment traps ammonia as ammonium ions, reducing its absorption into the bloodstream.

Side Effects

Lactulose may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects

  • Abdominal cramping: mild to moderate discomfort.
  • Flatulence: increased intestinal gas.
  • Diarrhea: loose stools, especially at higher doses.

Serious or Rare Side Effects

  • Severe dehydration: excessive fluid loss requiring medical care.
  • Significant electrolyte disturbances: marked hypokalemia or hyponatremia.
  • Allergic reaction: rash, urticaria, or angioedema.

Precautions & Warnings

When prescribing lactulose, several precautions should be considered to ensure safe and effective use.

  • Renal function: assess kidney status, as impaired clearance may affect fluid balance.
  • Electrolyte monitoring: check serum potassium and sodium, especially in long‑term therapy.
  • Diabetes mellitus: lactulose contains sugars; monitor blood glucose in diabetic patients.
  • Galactosemia: avoid use in patients with this inherited disorder.
  • Hepatic impairment: adjust dose and monitor ammonia levels in severe liver disease.
  • Store at ambient temperature: keep the solution in its original container, protect from moisture and direct sunlight.

Avoid Interactions

Lactulose can interact with other medicines, influencing efficacy or safety.

Major Interactions (Avoid)

  • Antacids: may reduce the osmotic effect of lactulose, decreasing its efficacy.
  • Diuretics: combined use can increase the risk of electrolyte imbalance and dehydration.
  • Broad‑spectrum antibiotics: may alter colonic flora, diminishing lactulose metabolism.

Moderate Interactions (Monitor Closely)

  • Probiotics: may enhance laxative effect, leading to increased stool frequency.
  • Other laxatives: additive effect may cause diarrhea or electrolyte loss.
  • Oral iron supplements: may increase gastrointestinal irritation when taken together.

Frequently Asked Questions

Lactulose Aiwa Pflaumenaroma is used as an osmotic laxative to treat chronic constipation and to lower elevated blood ammonia levels in patients with hepatic encephalopathy. By increasing water content in the colon, it facilitates softer stools and regular bowel movements, while also helping to improve neurological symptoms associated with liver‑related ammonia accumulation.

After oral administration, lactulose reaches the colon where bacterial enzymes split it into lactic and acetic acids. These short‑chain acids lower the colonic pH and create an osmotic gradient that draws water into the intestinal lumen, softening stool and stimulating peristalsis. In hepatic encephalopathy, the acidic environment converts ammonia to ammonium, reducing its absorption into the bloodstream.

The specific dose of lactulose is determined by the prescribing healthcare professional based on the individual’s condition, severity, and response to therapy. Typical starting regimens may vary, and the prescriber will adjust the amount to achieve the desired clinical effect while monitoring for tolerance and side effects.

Safety data for lactulose in pregnancy and lactation are limited. It is generally classified as a category C medication, meaning potential benefits may outweigh theoretical risks. Healthcare providers should evaluate the maternal condition and consider alternative therapies when appropriate, and advise breastfeeding mothers to monitor the infant for any adverse effects.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams across international markets. After receiving the request, the sales team will verify trade or institutional credentials, then provide pricing, availability, shipping details and any necessary import documentation.

Lactulose is an osmotic laxative, differing from stimulant laxatives such as senna, which increase intestinal motility, and from polymeric agents like polyethylene glycol, which also retain water but are not metabolized by colonic bacteria. Lactulose uniquely lowers ammonia levels, making it the preferred choice for patients with hepatic encephalopathy, whereas other laxatives lack this hepatic benefit.

The oral solution should be stored at ambient temperature, preferably below 25 °C. Keep the container tightly closed, protect it from moisture and direct sunlight, and retain it in the original packaging until use to maintain product stability.

Lactulose Aiwa Pflaumenaroma is taken orally as a liquid solution. The prescribed dose is measured with a calibrated dosing device or syringe, and it can be swallowed directly or mixed with a small amount of water, juice, or milk to improve palatability. Doses are usually spaced throughout the day as directed by the prescriber.

The most serious risks include severe dehydration and significant electrolyte disturbances such as hypokalemia or hyponatremia, which can arise from excessive fluid loss. Rarely, patients may experience allergic reactions manifesting as rash, urticaria, or angioedema. Prompt medical attention is required if any of these serious symptoms develop.

Lactulose should be avoided in individuals with known galactosemia, as they cannot metabolize the sugar component. It is also contraindicated in patients with intestinal obstruction, severe bowel perforation, or hypersensitivity to lactulose or any excipients in the formulation. Clinicians must assess each patient’s medical history before initiating therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.