Lactulose

After oral ingestion, lactulose reaches the colon unchanged, where bacterial enzymes split it into short‑chain fatty acids. These acids increase the osmotic pressure, drawing water into the intestinal lumen to soften stool, and they acidify the colon, converting ammonia to ammonium, which is then eliminated.

The dose of lactulose is individualized by the prescribing clinician based on the patient’s condition, response, and tolerance. Dosage may be adjusted over time, and patients should follow the specific instructions provided by their healthcare professional.

Safety data for lactulose during pregnancy and lactation are limited, and the product is classified as having an unknown pregnancy category. Healthcare providers should weigh potential benefits against possible risks before prescribing it to pregnant or nursing women.

To request lactulose, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Lactulose is an osmotic laxative, differing from stimulant laxatives such as senna that increase intestinal motility. It works by retaining water in the colon and also lowers ammonia levels, a benefit not shared by most other laxatives, making it useful for both constipation and hepatic encephalopathy.

Lactulose oral solution should be stored at ambient temperature, preferably below 25 °C. Keep the container tightly closed, protect it from moisture and direct sunlight, and avoid freezing. Follow any additional handling instructions on the label.

Lactulose is taken orally as a liquid solution. It is usually measured with a calibrated dosing device or spoon, mixed with water or a beverage if desired, and consumed according to the prescriber’s directions, typically once or twice daily.

Serious adverse events include severe electrolyte imbalance, marked dehydration, and rare allergic reactions such as rash or urticaria. Patients experiencing extreme diarrhea, faintness, or abdominal pain should seek medical attention promptly.

Lactulose is contraindicated in individuals with known hypersensitivity to the product, in patients with intestinal obstruction or perforation, and in those with severe dehydration until fluid balance is restored. Caution is also advised for patients with renal impairment or uncontrolled diabetes.