Product image of Lactulose Viatris Sante (Lactulose) supplied by GNH India

Lactulose Viatris Sante

Active Ingredient:
Lactulose
Origin:
EU

Lactulose Viatris Sante (Lactulose)

Lactulose, the active ingredient in Lactulose Viatris Sante, is an osmotic laxative presented as an oral dosage form for oral use. It is employed to treat constipation and to lower blood ammonia levels in patients with hepatic encephalopathy, particularly those with chronic liver disease.

GNH India supplies Lactulose Viatris Sante as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Viatris Sante

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Lactulose is used within the gastrointestinal and hepatic therapeutic pathways to manage specific conditions.

  • Constipation: softens stool and promotes regular bowel movements.
  • Hepatic encephalopathy: lowers systemic ammonia by converting it to ammonium for excretion.
  • Portal‑systemic encephalopathy: assists in reducing neurotoxic metabolites that contribute to cognitive impairment.

How It Works

  • After oral administration, lactulose reaches the colon where bacterial enzymes ferment it to short‑chain fatty acids, primarily lactic and acetic acid. This fermentation lowers colonic pH, creating an osmotic gradient that retains water in the lumen, softening stool and stimulating peristalsis. In hepatic encephalopathy, the acidic environment converts ammonia (NH3) to ammonium (NH4+), which is less readily absorbed, thereby decreasing systemic ammonia levels.

Side Effects

Lactulose may cause a range of adverse reactions, most of which are related to its osmotic activity in the gut.

Common Side Effects

  • Flatulence: increased intestinal gas production.
  • Abdominal cramping: intermittent stomach discomfort.
  • Diarrhea: loose stools that may lead to urgency.
  • Nausea: mild feeling of queasiness.
  • Bloating: sensation of abdominal fullness.

Serious or Rare Side Effects

  • Severe dehydration: excessive fluid loss requiring medical attention.
  • Electrolyte imbalance: abnormal sodium or potassium levels.
  • Allergic reaction: rash, itching, or swelling that may indicate hypersensitivity.

Precautions & Warnings

When prescribing lactulose, clinicians should consider several safety aspects.

  • Renal impairment: monitor fluid and electrolyte status closely.
  • Diabetes mellitus: observe blood glucose as carbohydrate load may affect control.
  • Pediatric use: dose must be individualized and supervised by a pediatric specialist.
  • Pregnancy: use only if the potential benefit outweighs any risk; consult a healthcare provider.
  • Galactosemia: contraindicated because lactulose contains galactose residues.
  • Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Lactulose can influence, or be influenced by, other medications.

Major Interactions (Avoid)

  • Antibiotics (e.g., neomycin): may reduce lactulose efficacy by altering gut flora.
  • Other laxatives (e.g., senna, bisacodyl): additive laxative effect can cause severe diarrhea.
  • Diuretics: increased risk of electrolyte disturbances when combined with lactulose.

Moderate Interactions (Monitor Closely)

  • Metformin: may exacerbate gastrointestinal side effects.
  • Rifampin: may affect lactulose metabolism and ammonia reduction.
  • Probiotics: may increase gas production; monitor patient tolerance.

Frequently Asked Questions

Lactulose Viatris Sante is indicated for the relief of constipation and for the management of hepatic encephalopathy, a neuropsychiatric complication of severe liver disease. In constipation, it softens stool and promotes regular bowel movements. In hepatic encephalopathy, it helps lower blood ammonia levels, reducing cognitive symptoms.

After oral ingestion, lactulose reaches the colon where intestinal bacteria ferment it into short‑chain fatty acids. This process lowers the colonic pH, creating an osmotic gradient that draws water into the lumen, softening stool. The acidic environment also converts ammonia to ammonium, which is trapped in the gut and eliminated, thereby decreasing systemic ammonia.

The dose of lactulose is individualized by the prescribing clinician based on the patient’s condition, age, renal function, and response. Healthcare providers determine the appropriate amount and frequency, and patients should follow the prescribed regimen without alteration.

Safety data for lactulose in pregnancy and lactation are limited. It should only be used when the potential benefit justifies any possible risk to the fetus or infant. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss use with their healthcare professional.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Lactulose is an osmotic laxative that works by retaining water in the colon, whereas stimulant laxatives (e.g., bisacodyl) increase intestinal motility. Compared with fiber supplements, lactulose provides a more rapid softening effect. Choice of therapy depends on patient tolerance, underlying conditions, and clinician preference.

Lactulose Viatris Sante should be stored at room temperature, below 25 °C, in its original packaging. Protect the product from moisture, excessive heat, and direct sunlight to maintain stability. No refrigeration is required for this oral formulation.

The medication is taken orally, usually as a liquid solution. It can be measured with a calibrated dosing device and may be mixed with water or a suitable beverage if needed for palatability. Patients should follow the dosing instructions provided by their prescriber.

Serious risks include severe dehydration, electrolyte disturbances (especially low sodium or potassium), and rare allergic reactions such as rash or swelling. Patients experiencing persistent diarrhea, dizziness, or signs of an allergic response should seek medical attention promptly.

Lactulose is contraindicated in individuals with known galactosemia because it contains galactose residues. Patients with severe intestinal obstruction, acute abdominal conditions, or hypersensitivity to lactulose should also avoid its use. Clinicians must evaluate each patient’s medical history before prescribing.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.