Product image of Lacudex (Chlorhexidine Gluconate) supplied by GNH India

Lacudex

Active Ingredient:
Chlorhexidine Gluconate
Origin:
EU

Lacudex (Chlorhexidine Gluconate)

Chlorhexidine gluconate, the active ingredient in Lacudex, is an antiseptic presented as an unspecified formulation for vaginal use. It acts as a vaginal antiseptic to reduce microbial colonisation and help prevent infections in women. Its broad‑spectrum activity targets bacteria, fungi and viruses, providing a reliable option for maintaining vaginal health.

GNH India supplies Lacudex as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Bioglan Ab

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Indications & Clinical Uses

Chlorhexidine gluconate is an antiseptic used in the vaginal tract to prevent infection and maintain hygiene.

  • Vaginal antiseptic: Reduces bacterial colonisation and helps prevent bacterial vaginosis.
  • Post‑operative vaginal care: Decreases risk of infection after gynecological procedures.
  • Gynecological examination preparation: Provides antiseptic cleansing before speculum insertion.

How It Works

  • Chlorhexidine gluconate is a cationic bisbiguanide that binds to negatively charged microbial cell membranes, disrupting membrane integrity and precipitating intracellular contents, which leads to cell death. Its broad‑spectrum activity affects Gram‑positive and Gram‑negative bacteria, fungi and some viruses, providing rapid and sustained antimicrobial action in the vaginal environment.

Side Effects

Chlorhexidine gluconate may cause local and systemic reactions, which are categorized as follows.

Common Side Effects

  • Local irritation: mild burning or stinging sensation.
  • Vaginal discharge: transient increased discharge.
  • Dryness: mild vaginal dryness.
  • Odor: temporary unpleasant smell.

Serious or Rare Side Effects

  • Allergic reaction: rash, hives, or swelling.
  • Severe irritation: ulceration or ulcerative lesions.

Precautions & Warnings

When using Lacudex, consider the following precautions to ensure safe and effective use.

  • Pregnancy: consult a healthcare provider before use.
  • Breastfeeding: limited data, use only if necessary.
  • Allergy: avoid if known hypersensitivity to chlorhexidine.
  • Concurrent vaginal products: do not use with other antiseptics simultaneously.
  • Store at room temperature: keep in the original pack, protect from moisture and heat.

Avoid Interactions

Chlorhexidine gluconate can interact with certain substances; relevant interactions include:

Major Interactions (Avoid)

  • Known hypersensitivity to chlorhexidine: product must not be used.
  • Use with latex condoms: may degrade latex, increasing risk of breakage.

Moderate Interactions (Monitor Closely)

  • Alcohol‑based vaginal products: may increase local irritation.
  • Other antiseptics: combined use can heighten mucosal irritation.
  • Damaged mucosa: systemic absorption may affect thyroid function, requiring monitoring.

Frequently Asked Questions

Lacudex contains chlorhexidine gluconate and is used as a vaginal antiseptic to reduce microbial colonisation and help prevent infections such as bacterial vaginosis or post‑procedural infections in women. It is applied locally in the vaginal canal under the direction of a healthcare professional.

Chlorhexidine gluconate is a cationic bisbiguanide that binds to negatively charged bacterial cell walls, disrupting membrane integrity and precipitating intracellular contents, leading to cell death. Its broad‑spectrum activity covers Gram‑positive and Gram‑negative bacteria, fungi and some viruses, providing rapid antimicrobial action.

The dosage and frequency of Lacudex are determined by the prescribing clinician based on the specific indication, severity of infection risk, and patient factors. Healthcare providers select the appropriate amount and duration in accordance with local guidelines and product labeling.

Safety data for chlorhexidine gluconate in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any potential risk, and the decision should be made by a qualified healthcare professional after evaluating the individual situation.

To place an order, submit an enquiry on the Lacudex product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Lacudex’s active ingredient, chlorhexidine gluconate, offers a broader antimicrobial spectrum and longer residual activity compared with many povidone‑iodine or simple alcohol‑based preparations. It is well‑tolerated when used as directed, though individual tolerance may vary.

Store Lacudex at room temperature, below 25 °C, in its original container, protected from moisture and direct sunlight. Keep the product out of reach of children and avoid exposure to extreme temperatures that could affect its stability.

Lacudex is applied intravaginally, typically using a pre‑filled applicator or measured dose as instructed by a healthcare professional. The product should be introduced gently into the vaginal canal, avoiding contact with the external genital skin unless directed otherwise.

The most serious risks include allergic reactions such as rash, hives, swelling, or anaphylaxis, and severe local irritation that may lead to ulceration. Immediate medical attention is required if any signs of a severe reaction occur.

Individuals with a known hypersensitivity to chlorhexidine or any component of the formulation should avoid Lacudex. It is also contraindicated in patients where the vaginal mucosa is severely damaged or ulcerated until the underlying condition is resolved.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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