Product image of Laevogo Pflaumenaroma (Lactulose, Liquid) supplied by GNH India

Laevogo Pflaumenaroma

Active Ingredient:
Lactulose, Liquid
Origin:
EU

Laevogo Pflaumenaroma (Lactulose, Liquid)

Lactulose, the active ingredient in Laevogo Pflaumenaroma, is an osmotic laxative presented as a liquid oral solution for oral use. It treats constipation and hepatic encephalopathy in adults and children as directed by a healthcare professional.

GNH India supplies Laevogo Pflaumenaroma as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Fresenius Kabi Austria Gmbh

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Indications & Clinical Uses

Lactulose is used to manage conditions related to bowel motility and hepatic ammonia accumulation.

  • Constipation: softens stools and promotes regular bowel movements.
  • Hepatic encephalopathy: lowers blood ammonia by acidifying colonic contents, helping prevent neuropsychiatric episodes.
  • Colonoscopy preparation: assists in clearing the colon to improve endoscopic visualization.

How It Works

  • Lactulose is a synthetic disaccharide that is not absorbed in the small intestine. In the colon it is metabolized by bacterial flora into short‑chain fatty acids, which increase osmotic pressure, draw water into the lumen, and lower pH. The resulting soft stools and acidic environment trap ammonia, facilitating its excretion and reducing systemic levels.

Side Effects

Lactulose may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Abdominal cramping or discomfort
  • Flatulence or increased gas
  • Diarrhea or loose stools
  • Nausea or mild vomiting
  • Bloating or a feeling of fullness
  • Thirst or mild dehydration

Serious or Rare Side Effects

  • Severe electrolyte imbalance (e.g., hyponatremia, hypokalemia)
  • Marked dehydration requiring medical attention
  • Allergic reactions such as rash, itching, or swelling
  • Acute hepatic decompensation in patients with advanced liver disease
  • Persistent watery diarrhea leading to fecal incontinence

Precautions & Warnings

Before initiating therapy, consider patient‑specific factors and monitor for complications.

  • Renal function: assess in patients with renal impairment, as reduced clearance may increase osmotic load.
  • Electrolytes: monitor serum electrolytes, especially potassium and sodium, during prolonged use.
  • Diabetes: observe blood glucose, as lactulose fermentation can affect glycemic control.
  • Intestinal obstruction: avoid use in known or suspected mechanical blockage.
  • Pediatric dosing: adjust dose carefully in children under medical supervision.
  • Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Lactulose can interact with other agents that affect gastrointestinal function or electrolyte balance.

Major Interactions (Avoid)

  • Antibiotics (e.g., quinolones): may reduce lactulose efficacy by altering gut flora.
  • Other laxatives (e.g., senna, bisacodyl): increase risk of excessive diarrhea and dehydration.
  • Loop or thiazide diuretics: may exacerbate electrolyte loss.

Moderate Interactions (Monitor Closely)

  • Antacids: can modify colonic pH, potentially affecting lactulose activity.
  • Probiotic supplements: may increase gas production and abdominal discomfort.
  • Oral hypoglycemic agents: monitor blood glucose as lactulose may influence carbohydrate absorption.

Frequently Asked Questions

Laevogo Pflaumenaroma contains lactulose, which is prescribed to relieve constipation and to manage hepatic encephalopathy by lowering blood ammonia levels. It is used in both adult and pediatric patients when a clinician determines that an osmotic laxative is appropriate for the individual's condition.

Lactulose reaches the colon unchanged, where intestinal bacteria break it down into short‑chain fatty acids. These acids increase the osmotic pressure in the lumen, drawing water into the bowel to soften stools. The resulting acidic environment also converts ammonia to ammonium, trapping it for excretion and thereby reducing systemic ammonia concentrations.

The dose of lactulose is individualized. A prescribing healthcare professional determines the amount, frequency, and duration based on the patient’s age, weight, severity of constipation or hepatic encephalopathy, and response to therapy. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety data for lactulose in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any possible risk to the fetus or infant. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss use with their obstetrician or healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, and will request verification of trade or institutional credentials. After confirmation, the sales team provides pricing, availability, shipping details (including any temperature requirements), and assists with import documentation.

Lactulose is an osmotic laxative that works by increasing colonic water content and acidifying the lumen, whereas agents such as polyethylene glycol (PEG) also draw water but do not significantly lower colonic pH. Lactulose has the added benefit of reducing ammonia in hepatic encephalopathy, a property not shared by most other laxatives.

Store the liquid oral solution at ambient temperature, preferably below 25 °C. Keep the container tightly closed, protect it from moisture, direct sunlight, and extreme temperature fluctuations. Do not freeze the product. If the solution appears discolored or contains particles, discard it and obtain a new supply.

The product is taken orally. The prescribed volume is measured with a calibrated dosing device (e.g., oral syringe or measuring cup) and ingested directly or mixed with a small amount of water or juice if needed. Dosing frequency and timing are set by the prescriber, and the medication should be taken with or without food as directed.

Serious adverse events, though uncommon, include severe electrolyte disturbances (such as hyponatremia or hypokalemia), marked dehydration, and allergic reactions that may present as rash, swelling, or difficulty breathing. Patients experiencing persistent watery diarrhea, faintness, or signs of an allergic response should seek medical attention promptly.

Lactulose should be avoided in individuals with known or suspected mechanical intestinal obstruction, severe inflammatory bowel disease, or acute abdominal conditions. Patients with uncontrolled diabetes, significant renal impairment, or those who have experienced severe allergic reactions to lactulose previously should also be evaluated carefully before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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