Product image of Lamera (Olmesartan Medoxomil, Amlodipine) supplied by GNH India

Lamera

Active Ingredient:
Olmesartan Medoxomil, Amlodipine
Origin:
EU

Lamera (Olmesartan Medoxomil, Amlodipine)

Olmesartan medoxomil and amlodipine, the active ingredient in Lamera, is an Angiotensin II receptor blocker (ARB) and calcium channel blocker presented as an oral tablet formulation for oral use. It is indicated for the management of hypertension in adult patients.
GNH India supplies Lamera as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Adamed S.R.L.

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Indications & Clinical Uses

  • Lamera combines an ARB and a calcium‑channel blocker to treat elevated blood pressure within the hypertension therapeutic area.
  • Hypertension: provides sustained blood‑pressure reduction in patients with essential hypertension, helping to lower the risk of cardiovascular complications.

How It Works

  • Olmesartan medoxomil selectively blocks the AT1 receptors for angiotensin II, preventing vasoconstriction and aldosterone release. Amlodipine inhibits L‑type calcium channels in vascular smooth muscle, leading to arterial vasodilation. The complementary actions produce additive blood‑pressure lowering effects without significant pharmacokinetic interaction.

Side Effects

Lamera may cause a range of adverse reactions, most of which are mild and reversible.

Common Side Effects

  • Headache: mild to moderate intensity.
  • Peripheral edema: swelling of ankles or feet.
  • Dizziness or light‑headedness, especially after standing.
  • Flushing: transient warmth or redness of the skin.

Serious or Rare Side Effects

  • Angio‑edema: rapid swelling of face, lips, or throat.
  • Severe hypotension: marked drop in blood pressure causing faintness.
  • Hepatic dysfunction: abnormal liver enzyme elevations.
  • Hyperkalemia: elevated potassium levels in blood.
  • Renal impairment: worsening kidney function in susceptible individuals.

Precautions & Warnings

Before initiating Lamera, consider patient‑specific factors and monitor relevant parameters.

  • Renal function: assess creatinine clearance and adjust therapy if needed.
  • Hepatic disease: use cautiously in patients with liver impairment.
  • Electrolytes: monitor potassium and sodium levels regularly.
  • Pregnancy and lactation: avoid use unless clearly indicated by a physician.
  • Store at ambient temperature: keep below 25 °C, retain in original packaging, and protect from moisture.

Avoid Interactions

Lamera can interact with several drug classes; awareness of the interaction potential helps optimize therapy.

Major Interactions (Avoid)

  • Potassium‑sparing diuretics or supplements: may cause hyperkalemia.
  • Strong CYP3A4 inhibitors (e.g., clarithromycin): can increase amlodipine exposure.

Moderate Interactions (Monitor Closely)

  • Non‑steroidal anti‑inflammatory drugs (NSAIDs): may attenuate antihypertensive effect and affect renal function.
  • Lithium: concurrent use may raise lithium levels.
  • Dual renin‑angiotensin system blockade (e.g., ACE inhibitors, other ARBs): increased risk of hypotension and renal dysfunction.

Frequently Asked Questions

Lamera is prescribed to lower elevated blood pressure in adults with essential hypertension. By combining an angiotensin II receptor blocker with a calcium‑channel blocker, it provides a synergistic effect that helps achieve target blood‑pressure levels and reduces cardiovascular risk.

Olmesartan medoxomil blocks the AT1 receptors that normally bind angiotensin II, a hormone that narrows blood vessels and stimulates aldosterone release. Inhibiting this pathway prevents vasoconstriction and fluid retention, contributing to a reduction in systemic blood pressure.

The appropriate dose of Lamera is determined by the prescribing clinician based on the patient’s blood‑pressure profile, renal function, and concomitant medications. Dosage adjustments are individualized and should follow the prescriber’s instructions.

Lamera is generally not recommended for use during pregnancy or while breastfeeding unless the potential benefit outweighs the risk. Both olmesartan and amlodipine cross the placenta and may affect the fetus, so a healthcare professional should evaluate alternatives.

To place an order, submit an enquiry on the Lamera product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and necessary import documentation.

Compared with single‑agent therapy, Lamera offers the convenience of a fixed‑dose combination, potentially improving adherence. It provides additive blood‑pressure reduction without the need for separate prescriptions, whereas alternatives may require multiple pills or different drug classes to achieve similar control.

Lamera tablets should be stored at ambient temperature, below 25 °C, in their original blister pack or container. Protect the product from excess moisture and direct sunlight to maintain stability throughout its shelf life.

Lamera is taken orally, usually once daily, with or without food, as directed by the prescriber. Swallow the tablet whole with a glass of water; do not crush, chew, or split the tablet unless specifically advised.

Serious risks include angio‑edema, severe hypotension, hyperkalemia, and significant renal impairment. Patients should seek immediate medical attention if they experience swelling of the face or throat, faintness, rapid heartbeat, or sudden changes in urine output.

Lamera is contraindicated in patients with known hypersensitivity to olmesartan, amlodipine, or any component of the formulation. It should also be avoided in individuals with severe hepatic impairment, uncontrolled heart failure, or a history of angio‑edema related to ARB or calcium‑channel blocker therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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