Product image of Lamisil Dermgel (Terbinafine) supplied by GNH India

Lamisil Dermgel

Active Ingredient:
Terbinafine
Origin:
EU

Lamisil Dermgel (Terbinafine)

Terbinafine, the active ingredient in Lamisil Dermgel, is a allylamine antifungal presented as a gel for topical use. It treats fungal skin infections such as athlete's foot, ringworm, jock itch and nail fungus in both adults and children.\n\nGNH India supplies Lamisil Dermgel as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Karo Healthcare Ab

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Indications & Clinical Uses

  • Terbinafine is used to treat superficial fungal infections of the skin and nails.\n\n- Tinea pedis: relieves itching, scaling and redness caused by athlete's foot.\n- Tinea corporis: clears ring‑shaped lesions and reduces inflammation.\n- Tinea cruris: diminishes redness and irritation of jock itch.\n- Tinea unguium: improves nail appearance and reduces fungal load in nail fungus.

How It Works

  • Terbinafine inhibits the fungal enzyme squalene epoxidase, blocking the conversion of squalene to ergosterol. This disruption leads to accumulation of toxic squalene and depletion of ergosterol, a vital component of fungal cell membranes, resulting in loss of membrane integrity and fungal cell death.

Side Effects

  • Common Side Effects:\n- Local irritation or burning at the application site.\n- Itching or mild redness.\n- Dryness or peeling of the treated skin.\n- Mild scaling or flaking.\n\nSerious or Rare Side Effects:\n- Severe allergic reaction such as angioedema or anaphylaxis.\n- Contact dermatitis with swelling or blistering.\n- Urticaria or widespread rash.\n- Rare cases of Stevens‑Johnson syndrome or toxic epidermal necrolysis.

Precautions & Warnings

  • Before using Lamisil Dermgel, consider the following precautions.\n\n- Assess for hypersensitivity: avoid use if known allergy to terbinafine or other allylamines.\n- Limit use to indicated areas: apply only to affected skin.\n- Avoid extensive broken skin: do not apply to large open wounds.\n- Monitor for systemic absorption: discontinue if systemic symptoms appear.\n- Pregnancy and lactation: consult a healthcare professional before use.\n- Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

  • Terbinafine gel may interact with other topical agents.\n\nMajor Interactions (Avoid):\n- Concurrent use of oral terbinafine: may increase systemic exposure.\n- Use with other topical antifungals containing azoles: risk of antagonism.\n- Co‑application with keratolytic agents on large areas: may increase skin absorption.\n\nModerate Interactions (Monitor Closely):\n- Use with corticosteroid creams: may mask local irritation.\n- Use with occlusive dressings: may increase skin penetration of the gel.

Frequently Asked Questions

Lamisil Dermgel is indicated for the topical treatment of dermatophyte infections such as athlete's foot (tinea pedis), ringworm (tinea corporis), jock itch (tinea cruris) and fungal nail infections (tinea unguium). It helps relieve symptoms and eradicate the underlying fungus.

Terbinafine blocks the fungal enzyme squalene epoxidase, preventing the synthesis of ergosterol, an essential component of fungal cell membranes. The resulting buildup of squalene and loss of ergosterol compromise membrane integrity, leading to fungal cell death.

The prescribed amount of Lamisil Dermgel is determined by the treating clinician based on the infection type, location and severity. Patients should follow the healthcare professional’s instructions for the frequency and duration of application.

Safety data for topical terbinafine in pregnancy and lactation are limited. Women who are pregnant, planning pregnancy, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using Lamisil Dermgel.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with azole‑based topical agents, terbinafine has a different mechanism of action and often achieves faster clinical resolution of dermatophyte infections. It is generally well‑tolerated, but choice of therapy should consider the specific pathogen, infection site and patient factors.

Lamisil Dermgel should be stored at room temperature, below 25 °C, in its original packaging. Keep the container tightly closed, protect it from moisture and direct sunlight to maintain product stability.

The gel is applied thinly to the affected skin area once or twice daily, as directed by a healthcare professional. The skin should be clean and dry before application, and hands should be washed after use to avoid accidental contact with other surfaces.

Although rare, serious adverse reactions can include severe allergic responses such as angioedema, anaphylaxis, or Stevens‑Johnson syndrome. Patients should discontinue use and seek immediate medical attention if they experience swelling, blistering, widespread rash or any signs of systemic allergy.

Individuals with a known hypersensitivity to terbinafine, other allylamines, or any component of the gel formulation should avoid its use. It is also contraindicated on extensive broken skin or in patients where a healthcare professional advises against topical antifungal therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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