Product image of Lamisil Dermgel (Terbinafine) supplied by GNH India

Lamisil Dermgel

Active Ingredient:
Terbinafine
Origin:
EU

Lamisil Dermgel (Terbinafine)

Terbinafine, the active ingredient in Lamisil Dermgel, is an allylamine antifungal presented as a gel for cutaneous (topical) use. It treats superficial fungal skin infections such as ringworm, athlete's foot, jock itch and tinea versicolor in patients as prescribed. It is indicated for use on intact skin and is applied once daily for the prescribed duration.

GNH India supplies Lamisil Dermgel as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring quality‑assured products and reliable logistics across multiple regions.

Manufacturer / TM Owner

Karo Pharma Ab

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Indications & Clinical Uses

Terbinafine is an allylamine antifungal that treats superficial dermatophyte infections of the skin.

  • Tinea corporis: reduces lesion size and clears the characteristic ring‑shaped rash.
  • Tinea pedis: alleviates itching and eliminates fungal growth on the feet.
  • Tinea cruris: resolves inflammation and scaling in the groin area.
  • Tinea versicolor: normalizes skin pigmentation by eradicating the causative yeast.

How It Works

  • Terbinafine inhibits the fungal enzyme squalene epoxidase, a key step in the biosynthesis of ergosterol, an essential component of fungal cell membranes. By blocking ergosterol production, the drug causes accumulation of toxic squalene and disrupts membrane integrity, leading to fungal cell death. The action is fungicidal against dermatophytes, yeasts and molds.

Side Effects

Topical terbinafine may cause local skin reactions and, rarely, systemic adverse events.

Common Side Effects

  • Itching: mild to moderate sensation at the application site.
  • Burning: transient heat sensation after application.
  • Redness: erythema of the treated skin.
  • Scaling: flaking or dry skin around the lesion.
  • Stinging: brief sharp discomfort on contact.
  • Contact dermatitis: localized allergic skin reaction.

Serious or Rare Side Effects

  • Severe allergic reaction: swelling, hives, or difficulty breathing.
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis: extensive skin detachment.
  • Systemic toxicity: rare liver enzyme elevation with extensive use.
  • Severe skin irritation: persistent ulceration or necrosis.
  • Anaphylaxis: rapid onset of systemic hypersensitivity.

Precautions & Warnings

Before using Lamisil Dermgel, consider the following safety measures.

  • Apply to intact skin only: avoid broken or inflamed areas.
  • Avoid contact with eyes and mucous membranes: wash hands thoroughly after each use.
  • Do not cover treated area with occlusive dressings: may increase systemic absorption.
  • Monitor for signs of hypersensitivity: discontinue if rash, swelling, or severe irritation occurs.
  • Store at room temperature: keep in the original container, protect from moisture and heat.

Avoid Interactions

Terbinafine gel has limited systemic absorption, but certain combinations may affect safety or efficacy.

Major Interactions (Avoid)

  • Concurrent oral terbinafine therapy: increases risk of systemic toxicity.
  • Use with other topical antifungal agents: may cause excessive local irritation.

Moderate Interactions (Monitor Closely)

  • Co‑administration with topical corticosteroids: may mask local irritation.
  • Use with occlusive bandages: can raise systemic absorption.
  • Combination with photosensitizing drugs: may increase sun sensitivity.

Frequently Asked Questions

Lamisil Dermgel is a prescription‑only topical gel containing terbinafine. It is used to treat superficial fungal skin infections such as ringworm (tinea corporis), athlete's foot (tinea pedis), jock itch (tinea cruris) and tinea versicolor. The gel is applied directly to the affected skin area as directed by a healthcare professional.

Terbinafine works by inhibiting the fungal enzyme squalene epoxidase, which is essential for producing ergosterol, a key component of fungal cell membranes. Blocking this pathway leads to an accumulation of squalene and a deficiency of ergosterol, disrupting membrane integrity and causing fungal cell death.

The dosage of Lamisil Dermgel is determined by the prescribing clinician based on the infection type, severity, and patient characteristics. Typically, a thin layer is applied once daily to the affected area for the duration specified in the prescription. Patients should follow the exact instructions provided by their healthcare provider.

Safety data for topical terbinafine during pregnancy and lactation are limited. Healthcare providers usually weigh the potential benefits against any possible risks. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss the use of Lamisil Dermgel with their doctor before starting treatment.

To order Lamisil Dermgel, submit an enquiry on the product page at gnhindia.com indicating the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request verification of trade or institutional credentials. The sales team then replies with pricing, availability, shipping details and any required import documentation.

Lamisil Dermgel (terbinafine) belongs to the allylamine class, which is fungicidal and often more effective against dermatophytes than many azole antifungals. Azoles, such as clotrimazole, are generally fungistatic and may require longer treatment courses. Terbinafine’s mechanism targeting squalene epoxidase can result in faster symptom relief for common skin infections.

Lamisil Dermgel should be stored at room temperature, below 25 °C, in its original packaging. Keep the container tightly closed, protect it from moisture and direct sunlight, and store it out of reach of children. Do not freeze the gel, and avoid exposing it to excessive heat.

Before application, wash and gently dry the affected skin area. Apply a thin layer of the gel to the lesion and the surrounding skin, then rub it in gently. Wash your hands after each application unless the hands are the treatment site. Follow the prescribing clinician’s instructions regarding frequency and duration.

Serious risks, though rare, include severe allergic reactions such as anaphylaxis, Stevens‑Johnson syndrome or toxic epidermal necrolysis, and significant skin irritation that may lead to ulceration. If any signs of systemic allergy, extensive rash, or worsening skin condition occur, discontinue use and seek immediate medical attention.

Patients with a known hypersensitivity to terbinafine, other allylamine antifungals, or any component of the gel should avoid its use. The product should not be applied to broken, inflamed, or infected skin unless specifically directed by a physician. Children under the age recommended by the prescriber should also be excluded.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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