Product image of Lamisil Dermgel (Terbinafine) supplied by GNH India

Lamisil Dermgel

Active Ingredient:
Terbinafine
Origin:
EU

Lamisil Dermgel (Terbinafine)

Terbinafine, the active ingredient in Lamisil Dermgel, is an allylamine antifungal presented as a 1% w/w gel for topical use. It treats fungal skin infections such as athlete's foot, ringworm, jock itch, hand and beard infections in both adults and children.

GNH India supplies Lamisil Dermgel as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Karo Healthcare Ab

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Indications & Clinical Uses

Lamisil Dermgel (terbinafine) is used to treat superficial dermatophyte infections of the skin.

  • Tinea pedis: relieves itching and clears the fungal infection on the feet.
  • Tinea corporis: eliminates ring‑shaped lesions caused by dermatophytes.
  • Tinea cruris: reduces inflammation and eradicates fungus in the groin area.
  • Tinea manuum: treats fungal infection of the hands.
  • Tinea barbae: clears infection of the beard region.

How It Works

  • Terbinafine inhibits the fungal enzyme squalene epoxidase, blocking the conversion of squalene to ergosterol. This disruption halts ergosterol synthesis, leading to accumulation of toxic squalene within the fungal cell membrane and ultimately causing fungal cell death.

Side Effects

Local application of Lamisil Dermgel may cause skin reactions.

Common Side Effects

  • Burning sensation at the application site
  • Itching or pruritus
  • Redness or erythema
  • Dryness or flaking of skin
  • Stinging feeling
  • Mild irritation

Serious or Rare Side Effects

  • Allergic reaction such as angioedema
  • Severe skin rash or contact dermatitis
  • Stevens‑Johnson syndrome (very rare)
  • Urticaria (hives)
  • Systemic hypersensitivity reactions
  • Bullous pemphigoid‑like eruptions

Precautions & Warnings

Before using Lamisil Dermgel, consider the following safety measures.

  • Pregnancy: safety not established; consult a healthcare professional before use.
  • Breastfeeding: unknown risk; weigh benefits against potential hazards.
  • Age: use in children only as directed by a prescriber.
  • Application area: avoid eyes, mucous membranes, and broken skin.
  • Concomitant skin conditions: do not apply to areas with eczema, psoriasis, or severe dermatitis.
  • Store at room temperature: keep in the original tube, protect from moisture and direct sunlight.

Avoid Interactions

Topical terbinafine has limited systemic interactions, but caution is advised.

Major Interactions (Avoid)

  • Concurrent oral terbinafine therapy: may increase systemic exposure.
  • Use with topical azole antifungals: potential antagonistic effect.

Moderate Interactions (Monitor Closely)

  • Alcohol‑based skin products: may increase local irritation.
  • Co‑application with corticosteroid creams: may reduce antifungal efficacy.
  • Exposure to phototoxic agents: may heighten skin sensitivity.

Frequently Asked Questions

Lamisil Dermgel is prescribed for superficial fungal skin infections such as athlete's foot (tinea pedis), ringworm (tinea corporis), jock itch (tinea cruris), hand infection (tinea manuum) and beard area infection (tinea barbae). It works by eliminating the dermatophyte organisms responsible for these conditions.

Terbinafine blocks the fungal enzyme squalene epoxidase, which is essential for producing ergosterol, a key component of the fungal cell membrane. Without ergosterol, toxic squalene accumulates, disrupting membrane integrity and leading to fungal cell death.

The dosage of Lamisil Dermgel is determined by the prescribing clinician based on the infection type, location and patient characteristics. The product is applied as a thin layer to the affected area once daily for the duration recommended by the healthcare professional.

Safety data for topical terbinafine in pregnancy and lactation are limited. Women who are pregnant, planning pregnancy, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using Lamisil Dermgel.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with azole topical agents, terbinafine has a different mechanism—blocking squalene epoxidase rather than inhibiting lanosterol 14α‑demethylase. This often results in a shorter treatment course and higher cure rates for dermatophyte infections, though individual response may vary.

Lamisil Dermgel should be stored at room temperature, below 25 °C. Keep the tube in its original packaging, protect it from moisture and direct sunlight, and ensure the cap is tightly closed when not in use.

Clean and dry the affected skin area, then apply a thin layer of the gel to the lesion and a small margin of surrounding skin. Rub gently until it disappears, and wash hands after application unless the hands are being treated.

Serious risks, though rare, include severe allergic reactions such as angioedema, widespread skin rash, Stevens‑Johnson syndrome, and systemic hypersensitivity. Patients should discontinue use and seek immediate medical attention if they experience swelling, blistering, or extensive rash.

Individuals with known hypersensitivity to terbinafine or any component of the gel should avoid its use. It should also not be applied to broken, inflamed or infected skin not caused by dermatophytes, and patients with uncontrolled systemic fungal infections should seek alternative therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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