Product image of Lamisil Dermgel (Terbinafine) supplied by GNH India

Lamisil Dermgel

Active Ingredient:
Terbinafine
Origin:
EU

Lamisil Dermgel (Terbinafine)

Terbinafine, the active ingredient in Lamisil Dermgel, is an allylamine antifungal presented as a gel for topical use. It inhibits fungal growth and is indicated for the treatment of superficial dermatophyte infections such as tinea pedis (athlete’s foot), tinea corporis (ringworm) and tinea cruris (jock itch) in both adults and children.

GNH India supplies Lamisil Dermgel as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring consistent quality and regulatory conformity. Through robust quality‑assurance processes and reliable logistics networks, the company supports timely delivery across regions.

Manufacturer / TM Owner

Karo Healthcare Ab

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Indications & Clinical Uses

  • Lamisil Dermgel (terbinafine) is used to treat superficial fungal infections caused by dermatophytes.
  • Tinea pedis: reduces symptoms and eliminates the causative dermatophyte on the feet.
  • Tinea corporis: clears ring‑shaped skin lesions caused by fungal infection.
  • Tinea cruris: resolves itching and rash in the groin area due to fungal growth.

How It Works

  • Terbinafine inhibits the fungal enzyme squalene epoxidase, a key step in the ergosterol biosynthesis pathway. By blocking this enzyme, the drug leads to accumulation of squalene, which is toxic to fungal cells, and depletes ergosterol, a vital component of the fungal cell membrane, resulting in impaired cell growth and eventual cell death.

Side Effects

Common Side Effects

  • Itching or mild burning at the application site.
  • Redness or erythema of the treated skin.
  • Stinging sensation during or after application.
  • Dryness or flaking of the skin.

Serious or Rare Side Effects

  • Severe allergic reaction (angioedema, anaphylaxis).
  • Contact dermatitis with extensive rash or swelling.
  • Systemic effects such as liver enzyme elevation (rare with topical use).

Precautions & Warnings

  • Before using Lamisil Dermgel, consider the following precautions.
  • Apply to intact skin: avoid broken or inflamed areas to reduce systemic absorption.
  • Avoid ocular contact: keep the product away from eyes.
  • Do not use on extensive body areas without medical advice.
  • Discontinue if severe irritation occurs: seek medical evaluation.
  • Pregnancy and lactation: consult a healthcare professional before use.
  • Store at ambient temperature: keep the gel in the original container, protect from light and moisture.

Avoid Interactions

Lamisil Dermgel may interact with other topical or systemic agents.

Major Interactions (Avoid)

  • Systemic terbinafine therapy: concurrent use may increase systemic exposure and risk of toxicity.
  • Other topical antifungal agents containing azoles: may cause additive skin irritation.

Moderate Interactions (Monitor Closely)

  • Corticosteroid creams: may mask local reactions, monitor skin condition.
  • Alcohol‑based skin products: may increase dryness, observe for irritation.
  • Hepatotoxic chemotherapeutic agents: monitor hepatic function if extensive topical use is required.

Frequently Asked Questions

Lamisil Dermgel is a topical gel containing terbinafine that is used to treat superficial dermatophyte infections of the skin, including athlete’s foot (tinea pedis), ringworm (tinea corporis) and jock itch (tinea cruris). It works by eliminating the fungi that cause these conditions.

Terbinafine blocks the fungal enzyme squalene epoxidase, which is essential for producing ergosterol, a key component of the fungal cell membrane. Inhibiting this step leads to toxic buildup of squalene and loss of membrane integrity, ultimately killing the fungus.

The prescribed dose is determined by a healthcare professional. Typically, a thin layer of the gel is applied to the affected area once daily for the duration recommended by the prescriber, which varies according to the infection type and severity.

Safety data for topical terbinafine in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using the product.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with azole antifungals such as clotrimazole, terbinafine has a different mechanism of action and often requires a shorter treatment course for dermatophyte infections. It is generally well‑tolerated, but choice of therapy should be guided by the specific pathogen, infection site and patient factors.

Store the gel at ambient temperature, away from direct sunlight and moisture. Keep it in the original container with the cap tightly closed. Do not freeze the product, and keep it out of reach of children.

Clean and dry the affected skin area before use. Apply a thin, even layer of the gel to the lesion and gently rub it in. Wash hands after application unless the hands are the treatment site. Follow the prescriber’s instructions regarding frequency and duration.

The most serious risks include severe allergic reactions such as angioedema or anaphylaxis, extensive contact dermatitis, and, rarely, systemic effects like liver enzyme elevation if large amounts are absorbed. Immediate medical attention is required if any of these symptoms develop.

Individuals with a known hypersensitivity to terbinafine or any component of the gel should avoid its use. It is also contraindicated on large areas of broken or severely inflamed skin without medical supervision, and caution is advised for patients with pre‑existing liver disease.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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