Product image of Lamisil Lotion (Terbinafine Hydrochloride) supplied by GNH India

Lamisil Lotion

Active Ingredient:
Terbinafine Hydrochloride
Origin:
EU

Lamisil Lotion (Terbinafine Hydrochloride)

Terbinafine Hydrochloride, the active ingredient in Lamisil Lotion, is an allylamine antifungal presented as a 1% lotion for topical use. It treats superficial fungal infections such as athlete’s foot, ringworm and tinea versicolor in both adults and children by disrupting fungal cell membrane synthesis, leading to eradication of the pathogen.

GNH India supplies Lamisil Lotion as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Karo Healthcare Ab

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Indications & Clinical Uses

Terbinafine is an allylamine antifungal used to treat superficial dermatophyte infections.

  • Tinea corporis: clears ring‑shaped skin lesions caused by dermatophytes.
  • Tinea cruris: resolves itching and erythema in the groin area.
  • Tinea pedis: eliminates athlete’s foot symptoms on the feet.
  • Tinea versicolor: reduces discolored patches on the trunk and shoulders.
  • Superficial fungal infections: provides overall clearance of skin fungal overgrowth.

How It Works

  • Terbinafine inhibits the fungal enzyme squalene epoxidase, which blocks the conversion of squalene to ergosterol. This interruption leads to accumulation of toxic squalene and depletion of ergosterol, a vital component of the fungal cell membrane, ultimately causing fungal cell death and resolution of the infection.

Side Effects

Common Side Effects

  • Itching or mild burning at the application site.
  • Redness or localized erythema.
  • Skin scaling or flaking.
  • Stinging sensation.
  • Dryness of the treated area.
  • Minor irritation or discomfort.

Serious or Rare Side Effects

  • Severe allergic reaction with swelling of face, lips or tongue.
  • Widespread rash or urticaria.
  • Contact dermatitis extending beyond the application site.
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis (very rare).
  • Significant swelling or blistering of the skin.
  • Systemic hypersensitivity requiring medical attention.

Precautions & Warnings

Before using Lamisil Lotion, consider the following precautions.

  • Pregnancy: safety not established; consult a healthcare professional before use.
  • Breastfeeding: unknown safety; weigh potential risks and benefits with a clinician.
  • Age: follow prescriber guidance for children and adolescents.
  • Damaged skin: avoid applying to open wounds, burns or severely irritated skin.
  • Concurrent topical agents: do not combine with other antifungal or irritant creams unless directed.
  • Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Terbinafine Lotion has limited systemic absorption, but potential interactions should be considered.

Major Interactions (Avoid)

  • Concurrent systemic terbinafine therapy: may increase overall drug exposure and risk of systemic side effects.

Moderate Interactions (Monitor Closely)

  • Use with other topical irritants (e.g., corticosteroids) may heighten skin irritation.
  • Application under occlusive dressings can enhance absorption; monitor for local adverse reactions.
  • Co‑application with other antifungal agents without medical advice may alter efficacy.

Frequently Asked Questions

Lamisil Lotion is a topical antifungal medication indicated for the treatment of superficial fungal infections, including tinea corporis (ringworm), tinea cruris (jock itch), tinea pedis (athlete’s foot) and tinea versicolor. It works on the skin surface to eliminate the fungi responsible for these conditions, helping to relieve itching, redness and scaling.

Terbinafine, the active ingredient in Lamisil Lotion, blocks the fungal enzyme squalene epoxidase. This inhibition prevents the synthesis of ergosterol, an essential component of the fungal cell membrane, leading to accumulation of squalene and cell death. By targeting this pathway, terbinafine effectively eradicates dermatophytes and other susceptible fungi on the skin.

The specific amount and frequency of application are determined by the prescribing healthcare professional. Typically, a thin layer is applied to the affected area once daily for the duration recommended by the prescriber, which may vary depending on the infection type and severity.

Safety data for terbinafine lotion in pregnancy and lactation are limited. It should be used only if the potential benefit justifies any possible risk to the fetus or infant. Women who are pregnant, planning pregnancy, or breastfeeding should discuss use with their healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide. After receiving the request, the sales team will verify trade or institutional credentials and respond with pricing, availability, shipping details (including any cold‑chain requirements) and required import documentation.

Lamisil Lotion (allylamine) differs from azole antifungals by targeting squalene epoxidase rather than lanosterol 14α‑demethylase. This distinct mechanism often results in faster fungal clearance and lower rates of resistance for dermatophyte infections. Azoles may be preferred for certain yeasts, while terbinafine is generally favored for dermatophyte‑related skin conditions.

Store Lamisil Lotion at room temperature, ideally below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the cap is tightly closed when not in use. Do not freeze or expose the lotion to extreme temperatures.

Clean and dry the affected skin area before use. Apply a thin, even layer of the lotion to the lesion and a small margin of surrounding skin, gently rubbing it in until it disappears. Wash hands after application unless the hands are being treated. Follow the prescriber’s instructions regarding frequency and treatment duration.

Serious adverse reactions, although rare, include severe allergic responses such as facial swelling, difficulty breathing, widespread rash, Stevens‑Johnson syndrome or toxic epidermal necrolysis. If any of these occur, discontinue use immediately and seek medical attention. Prompt reporting of severe skin reactions is essential.

Individuals with a known hypersensitivity to terbinafine, other allylamine antifungals, or any component of the formulation should avoid using Lamisil Lotion. It is also contraindicated on severely damaged, inflamed or broken skin unless directed by a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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