Product image of Lamisil (Terbinafine) supplied by GNH India

Lamisil

Active Ingredient:
Terbinafine
Origin:
EU

Lamisil (Terbinafine)

Terbinafine, the active ingredient in Lamisil, is an allylamine antifungal presented as a topical formulation for cutaneous use. It treats fungal skin infections such as athlete's foot, ringworm, jock itch, and related conditions in patients of all ages.

GNH India supplies Lamisil as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Novartis Farma S.P.A.

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Indications & Clinical Uses

Lamisil is an allylamine antifungal used to treat superficial fungal infections of the skin.

  • Tinea pedis: reduces itching and clears infection of the feet.
  • Tinea corporis: eliminates ring‑shaped lesions on the body.
  • Tinea cruris: relieves jock itch symptoms and eradicates the fungus.
  • Tinea versicolor: restores normal skin coloration by clearing yeast overgrowth.
  • Superficial dermatophytosis: treats various skin‑surface fungal infections.

How It Works

  • Terbinafine inhibits the fungal enzyme squalene epoxidase, which blocks the conversion of squalene to ergosterol. This disruption impairs the synthesis of ergosterol, an essential component of fungal cell membranes, leading to accumulation of toxic squalene and ultimately causing fungal cell death.

Side Effects

Topical terbinafine may cause local skin reactions.

Common Side Effects

  • Itching or pruritus at the application site.
  • Burning or stinging sensation.
  • Redness or erythema.
  • Dryness or scaling of the skin.
  • Mild irritation or rash.

Serious or Rare Side Effects

  • Severe allergic reaction (e.g., angioedema, anaphylaxis).
  • Contact dermatitis with blistering.
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Systemic absorption leading to liver enzyme abnormalities (rare).

Precautions & Warnings

Before using Lamisil, consider the following safety measures.

  • Assess hypersensitivity: avoid if known allergy to terbinafine or similar agents.
  • Avoid broken skin: do not apply to open wounds or inflamed areas.
  • Eye protection: keep product away from eyes and mucous membranes.
  • Duration limit: use only for the prescribed treatment period.
  • Extensive use monitoring: watch for signs of systemic absorption in large‑area applications.
  • Store at room temperature: keep in original container, protect from moisture and light.

Avoid Interactions

Terbinafine topical has limited systemic interactions, but caution is advised with certain co‑administered products.

Major Interactions (Avoid)

  • Concurrent use of other topical antifungals containing the same active ingredient.
  • Application with potent topical corticosteroids that may mask irritation.

Moderate Interactions (Monitor Closely)

  • Simultaneous oral terbinafine therapy may increase systemic exposure.
  • Use with other skin irritants (e.g., chemical peels) may exacerbate local reactions.
  • Combination with photosensitizing agents may increase sun sensitivity.

Frequently Asked Questions

Lamisil (terbinafine) is applied to the skin to treat superficial fungal infections such as athlete's foot (tinea pedis), ringworm (tinea corporis), jock itch (tinea cruris), tinea versicolor, and other dermatophytoses. It works by eliminating the fungus that causes these skin conditions.

Terbinafine blocks the fungal enzyme squalene epoxidase, preventing the synthesis of ergosterol, a vital component of fungal cell membranes. Without ergosterol, the fungal cell membrane becomes defective, leading to accumulation of toxic substances and ultimately fungal cell death.

The specific dose and duration of Lamisil are determined by the prescribing healthcare professional based on the type and severity of the infection, the area of skin involved, and patient factors. Patients should follow the prescriber’s instructions and the product label.

Safety data for topical terbinafine in pregnancy and lactation are limited. Healthcare providers should weigh the potential benefits against any possible risks before prescribing Lamisil to pregnant or nursing individuals. Patients should discuss their situation with a qualified professional.

To request Lamisil, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide. After submission, the sales team will verify trade or institutional credentials and respond with pricing, availability, shipping details and any required import documentation.

Lamisil (terbinafine) belongs to the allylamine class, which differs from azole antifungals that inhibit lanosterol 14α‑demethylase. Terbinafine often provides rapid fungicidal activity and may require shorter treatment courses for certain skin infections, while azoles are typically fungistatic and may be used for a broader range of fungal species.

Store Lamisil at room temperature, below 25 °C. Keep the product in its original packaging, protect it from moisture, excessive heat and direct sunlight to maintain its stability and effectiveness.

Apply a thin layer of the cream or gel to the affected skin area once or twice daily, as directed by the prescriber. Wash and dry the area before application, and avoid covering the treated skin with airtight dressings unless instructed otherwise.

While rare, serious adverse reactions can include severe allergic responses such as angioedema, anaphylaxis, Stevens‑Johnson syndrome, or toxic epidermal necrolysis. Patients should seek immediate medical attention if they experience swelling of the face, lips, tongue, or widespread skin blistering.

Individuals with a known hypersensitivity to terbinafine, other allylamine antifungals, or any component of the formulation should avoid using Lamisil. It is also contraindicated on severely damaged or broken skin and should be used with caution in patients with extensive skin involvement.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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