Product image of Lamisil (Terbinafine) supplied by GNH India

Lamisil

Active Ingredient:
Terbinafine
Origin:
EU

Lamisil (Terbinafine)

Terbinafine, the active ingredient in Lamisil, is an allylamine antifungal presented as a topical formulation for skin application. It is used to treat dermatophyte infections of the skin, hair and nails in both adults and children when prescribed by a qualified healthcare professional.

GNH India supplies Lamisil as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring consistent quality and regulatory compliance across markets. The company adheres to WHO GMP guidelines and provides comprehensive documentation for import and distribution.

Manufacturer / TM Owner

Karo Healthcare Ab

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Indications & Clinical Uses

Lamisil (terbinafine) is used to treat superficial fungal infections caused by dermatophytes.

  • Tinea pedis: relieves itching and clears fungal infection of the feet.
  • Tinea corporis: eliminates ring‑shaped skin lesions caused by dermatophytes.
  • Tinea cruris: resolves fungal infection of the groin and inner thigh area.
  • Onychomycosis: improves appearance and reduces fungal load in infected toenails.

How It Works

  • Terbinafine inhibits the fungal enzyme squalene epoxidase, which blocks the conversion of squalene to ergosterol. This leads to an accumulation of squalene and a depletion of ergosterol, disrupting the fungal cell membrane structure and causing cell death.

Side Effects

Terbinafine topical therapy may cause local skin reactions.

Common Side Effects

  • Itching: mild to moderate sensation at the application site.
  • Redness: localized erythema.
  • Burning sensation: transient warmth or stinging.
  • Scaling: flaking of the treated skin.
  • Dryness: reduced moisture at the site.
  • Irritation: mild discomfort or prickling.

Serious or Rare Side Effects

  • Allergic reaction: rash, swelling, or hives.
  • Severe skin rash: extensive redness or blistering.
  • Facial or throat swelling: signs of angioedema.
  • Difficulty breathing: possible anaphylactic response.
  • Liver toxicity: rare systemic involvement.
  • Contact dermatitis: persistent inflammation.

Precautions & Warnings

Before using Lamisil, consider the following safety measures.

  • Apply to clean, dry skin: follow label instructions for proper preparation.
  • Avoid use on broken skin: risk of increased irritation.
  • Do not cover treated area with occlusive dressings: may enhance absorption.
  • Discontinue if severe irritation occurs: seek medical advice promptly.
  • Store at room temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Terbinafine may interact with other medicines; monitor accordingly.

Major Interactions (Avoid)

  • Concurrent systemic antifungals (e.g., itraconazole): increased hepatotoxicity risk.
  • CYP2D6 inhibitors (e.g., fluoxetine): may raise terbinafine plasma levels.
  • Warfarin: monitor INR closely due to potential anticoagulant effect.

Moderate Interactions (Monitor Closely)

  • Alcohol consumption: may add strain to liver function.
  • Use with other topical agents (e.g., corticosteroids): could alter drug absorption.
  • Co‑application with skin irritants: increased risk of local irritation.

Frequently Asked Questions

Lamisil (terbinafine) is indicated for the topical treatment of superficial fungal infections such as athlete’s foot (tinea pedis), ringworm of the body (tinea corporis), groin infection (tinea cruris) and fungal nail infection (onychomycosis).

Terbinafine blocks the fungal enzyme squalene epoxidase, preventing the synthesis of ergosterol, an essential component of the fungal cell membrane. The resulting membrane disruption leads to fungal cell death.

The dosage and duration of Lamisil are determined by the prescribing healthcare professional based on the type and severity of the infection, as well as patient‑specific factors.

Safety data for topical terbinafine in pregnancy and lactation are limited. Use only if the potential benefit justifies any potential risk and after consultation with a qualified healthcare provider.

Submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Terbinafine belongs to the allylamine class and often provides faster clinical cure rates for dermatophyte infections compared with azole creams, while having a favorable safety profile for short‑term topical use.

Store Lamisil at room temperature, below 25 °C, in its original packaging. Keep the product away from moisture, direct sunlight and extreme heat to maintain stability.

Clean and dry the affected skin area, then apply a thin layer of the cream or gel as directed, usually once or twice daily. Wash hands after application unless treating the hands themselves.

Serious adverse reactions are rare but may include severe allergic responses such as rash, swelling, angioedema, difficulty breathing, or signs of liver toxicity. Discontinue use and seek medical attention if these occur.

Individuals with known hypersensitivity to terbinafine or any component of the formulation should avoid using Lamisil. Patients with extensive broken skin or severe liver disease should consult a healthcare professional before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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