Product image of Lamisil (Terbinafine Hydrochloride) supplied by GNH India

Lamisil

Active Ingredient:
Terbinafine Hydrochloride
Origin:
EU

Lamisil (Terbinafine Hydrochloride)

Terbinafine Hydrochloride, the active ingredient in Lamisil, is an allylamine antifungal presented as a topical formulation for skin application. It is indicated for the treatment of superficial dermatophytosis, including athlete’s foot (tinea pedis), ringworm (tinea corporis), and jock itch (tinea cruris) in both adults and children.

GNH India supplies Lamisil as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring consistent quality and regulatory compliance across markets through a robust supply chain and comprehensive documentation plus reliable logistics.

Manufacturer / TM Owner

Karo Pharma Ab

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Lamisil (terbinafine) is an allylamine antifungal that targets dermatophyte infections of the skin.
  • Tinea pedis: reduces fungal growth and clears symptoms of athlete’s foot.
  • Tinea corporis: treats ringworm lesions on the body.
  • Tinea cruris: resolves jock itch caused by dermatophytes.

How It Works

  • Terbinafine inhibits the fungal enzyme squalene epoxidase, a key step in the ergosterol biosynthesis pathway. By blocking this enzyme, intracellular squalene accumulates while ergosterol production falls, disrupting the integrity of the fungal cell membrane and leading to cell death. The selective inhibition of fungal squalene epoxidase provides a high therapeutic index with limited effect on human cells.

Side Effects

Topical terbinafine may cause local or systemic adverse reactions.

Common Side Effects

  • Application site itching
  • Redness or irritation
  • Burning sensation
  • Dryness of skin
  • Scaling
  • Mild rash

Serious or Rare Side Effects

  • Severe allergic reaction (anaphylaxis)
  • Contact dermatitis
  • Liver enzyme elevation (rare systemic absorption)
  • Bullous skin lesions
  • Photosensitivity

Precautions & Warnings

Use of Lamisil should be considered in the context of patient‑specific factors and proper storage.

  • Pregnancy: consult a healthcare provider before use.
  • Breastfeeding: discuss potential risks with a professional.
  • Age: safety not established in children under 2 years.
  • Concomitant skin conditions: avoid application on damaged skin.
  • Allergy: discontinue if hypersensitivity occurs.
  • Store at room temperature: keep in original container, protect from moisture and light.

Avoid Interactions

Terbinafine may interact with other agents; awareness of interaction severity is important.

Major Interactions (Avoid)

  • Strong CYP450 inhibitors: may increase systemic exposure.
  • Concurrent use of other topical antifungals: risk of additive irritation.
  • Systemic terbinafine: avoid simultaneous use to prevent overdose.

Moderate Interactions (Monitor Closely)

  • Alcohol: may increase liver enzyme risk if systemic absorption occurs.
  • Hepatotoxic drugs: monitor liver function during combined therapy.
  • Warfarin: potential for increased anticoagulant effect; monitor INR.

Frequently Asked Questions

Lamisil (terbinafine) is used to treat superficial fungal infections of the skin, specifically tinea pedis (athlete’s foot), tinea corporis (ringworm), and tinea cruris (jock itch). It works by eliminating the dermatophyte fungi that cause these conditions, helping to relieve itching, redness, and scaling.

Terbinafine blocks the fungal enzyme squalene epoxidase, which is essential for producing ergosterol, a key component of fungal cell membranes. Inhibiting this step leads to a buildup of squalene and a shortage of ergosterol, destabilizing the membrane and causing fungal cell death.

The dosage of Lamisil is determined by the prescribing healthcare professional based on the specific infection, patient age, and product formulation. Patients should follow the prescriber’s instructions and the product label for application frequency and duration.

Safety data for topical terbinafine during pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using Lamisil.

To order Lamisil, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Lamisil belongs to the allylamine class, which directly inhibits squalene epoxidase, whereas many other topical antifungals (e.g., azoles) target lanosterol 14‑α‑demethylase. Terbinafine often provides rapid symptom relief and has a favorable safety profile, making it a common first‑line option for dermatophyte infections.

Lamisil should be stored at room temperature, below 25 °C, in its original packaging. Keep the product away from excessive heat, moisture, and direct sunlight to maintain its stability and effectiveness.

Lamisil is applied topically to the affected skin area, usually once or twice daily as directed by the prescriber. The skin should be clean and dry before application, and the medication should be rubbed in gently until fully absorbed.

While rare, serious adverse reactions can include severe allergic responses such as anaphylaxis, extensive contact dermatitis, and, in cases of significant systemic absorption, liver enzyme elevations. Patients should seek medical attention if they experience signs of a serious reaction.

Individuals with a known hypersensitivity to terbinafine or any component of the formulation should avoid using Lamisil. It is also not recommended for children under two years of age unless specifically prescribed, and caution is advised for patients with existing liver disease.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.