Product image of Lamivudina Aurovitas (Lamivudine) supplied by GNH India

Lamivudina Aurovitas

Active Ingredient:
Lamivudine
Origin:
EU

Lamivudina Aurovitas (Lamivudine)

Lamivudine, the active ingredient in Lamivudina Aurovitas, is a nucleoside reverse transcriptase inhibitor presented as an oral dosage form for oral use. It is used to treat Human Immunodeficiency Virus (HIV) infection and chronic hepatitis B infection in adults and children.
GNH India supplies Lamivudina Aurovitas as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Aurovitas Spain,s.A.U.

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Indications & Clinical Uses

Lamivudina Aurovitas is a nucleoside reverse transcriptase inhibitor indicated for viral infections affecting the immune and hepatic systems.

  • HIV infection: reduces viral load and helps restore immune function.
  • Chronic hepatitis B infection: suppresses HBV replication and reduces liver inflammation.
  • Prevention of mother‑to‑child transmission of HIV: lowers the risk of vertical transmission when used in combination therapy.

How It Works

  • Lamivudine is a synthetic nucleoside analogue that is phosphorylated intracellularly to its active triphosphate form. The active metabolite competes with natural deoxycytidine triphosphate for incorporation into viral DNA by reverse transcriptase, causing premature chain termination and thereby inhibiting viral replication in HIV and hepatitis B virus.

Side Effects

Lamivudina Aurovitas may cause a range of adverse reactions.

Common Side Effects

  • Nausea: mild to moderate gastrointestinal discomfort.
  • Headache: transient cranial pain.
  • Fatigue: general feeling of tiredness.
  • Diarrhea: loose stools, usually self‑limiting.

Serious or Rare Side Effects

  • Lactic acidosis: metabolic disturbance requiring immediate medical attention.
  • Severe hepatotoxicity: liver enzyme elevation or failure.
  • Pancreatitis: inflammation of the pancreas with abdominal pain.

Precautions & Warnings

Before initiating therapy, clinicians should consider several safety measures.

  • Monitor liver function: regular testing is advised for patients with hepatic disease.
  • Assess renal function: dose adjustment may be required in renal impairment.
  • Screen for hepatitis B reactivation: periodic HBV DNA monitoring is recommended.
  • Counsel on pregnancy: the safety profile is not fully established; discuss risks with a healthcare provider.
  • Store at ambient temperature: keep below 25°C, protect from moisture and retain in original packaging.

Avoid Interactions

Lamivudina Aurovitas can interact with other medicines, influencing efficacy or toxicity.

Major Interactions (Avoid)

  • Didanosine: combined use increases risk of pancreatitis.
  • Stavudine: concurrent therapy may enhance mitochondrial toxicity.
  • Ribavirin: co‑administration can heighten hematologic toxicity.

Moderate Interactions (Monitor Closely)

  • Alcohol: may exacerbate liver injury.
  • Antacids: could affect lamivudine absorption if taken simultaneously.
  • Protease inhibitors: may alter lamivudine plasma concentrations.

Frequently Asked Questions

Lamivudina Aurovitas contains lamivudine, an antiretroviral medication indicated for the treatment of Human Immunodeficiency Virus (HIV) infection and chronic hepatitis B infection. It helps lower viral load and improve immune function in HIV patients and suppresses hepatitis B virus replication in liver disease.

Lamivudine is a nucleoside analogue that, after cellular phosphorylation, becomes an active triphosphate. This active form competes with natural nucleotides for incorporation into viral DNA by reverse transcriptase, causing premature chain termination and preventing the virus from replicating its genome.

The specific dose of lamivudine is determined by the prescribing clinician based on the patient’s condition, age, weight, renal function and other factors. Healthcare providers follow established guidelines and adjust the regimen as needed for optimal therapeutic effect.

The safety of lamivudine in pregnancy and lactation has not been fully established. It should only be used if the potential benefit justifies the possible risk to the fetus or infant, and the decision must be made by a qualified healthcare professional.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Lamivudine belongs to the nucleoside reverse transcriptase inhibitor (NRTI) class, offering a favorable safety profile and convenient oral administration. Compared with some older NRTIs, it has lower mitochondrial toxicity and is often combined with other agents to form highly effective combination regimens for HIV and hepatitis B.

Lamivudina Aurovitas should be stored at ambient temperature, preferably below 25 °C, in its original packaging to protect it from moisture and light. Keep the product out of reach of children and avoid exposure to extreme temperatures.

Lamivudina Aurovitas is taken orally, usually with or without food, as directed by the prescribing clinician. The tablets are swallowed whole with a glass of water and the dosing schedule is based on the individual treatment plan.

Serious adverse events, although rare, can include lactic acidosis, severe hepatotoxicity, and pancreatitis. Patients should be monitored for signs such as unexplained fatigue, abdominal pain, jaundice or rapid weight loss, and seek immediate medical attention if these occur.

Lamivudina Aurovitas is contraindicated in individuals with known hypersensitivity to lamivudine or any of the tablet’s excipients. Patients with severe renal impairment may require dose adjustment, and those with active liver disease should be closely monitored by their healthcare provider.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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