Product image of Lamivudina Mylan (Lamivudine) supplied by GNH India

Lamivudina Mylan

Active Ingredient:
Lamivudine
Origin:
EU

Lamivudina Mylan (Lamivudine)

Lamivudine, the active ingredient in Lamivudina Mylan, is a nucleoside reverse transcriptase inhibitor (NRTI) presented as an oral tablet for oral use. It is prescribed to treat HIV‑1 infection and chronic hepatitis B in both adults and children as part of approved therapeutic regimens.

GNH India supplies Lamivudina Mylan as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring consistent quality, regulatory compliance and reliable logistics across multiple regions and timely delivery to meet patient needs globally.

Manufacturer / TM Owner

Mylan S.P.A.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Lamivudine is an NRTI used to manage viral infections that rely on reverse transcriptase.

  • HIV‑1 infection (adults): Reduces viral load as part of combination antiretroviral therapy.
  • HIV‑1 infection (children): Suppresses viral replication in pediatric patients within approved regimens.
  • Chronic hepatitis B infection: Inhibits hepatitis B virus replication, improving liver function and disease outcomes.

How It Works

  • Lamivudine is a nucleoside analogue that mimics the natural nucleoside cytidine. After intracellular phosphorylation to its active triphosphate form, it competes with deoxy‑cytidine triphosphate for incorporation into viral DNA by HIV reverse transcriptase or hepatitis B polymerase. Incorporation results in premature chain termination, halting viral DNA synthesis and thereby suppressing viral replication. The drug exhibits high selectivity for viral enzymes, sparing host DNA polymerases, which contributes to its favorable safety profile.

Side Effects

Lamivudine may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Headache: mild to moderate intensity.
  • Nausea: occasional gastrointestinal upset.
  • Fatigue: general tiredness.
  • Diarrhea: loose stools.

Serious or Rare Side Effects

  • Lactic acidosis: metabolic disturbance requiring immediate medical attention.
  • Severe hepatomegaly with steatosis: liver enlargement with fat accumulation.
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis: severe skin reactions.

Precautions & Warnings

When prescribing lamivudine, clinicians should observe several precautionary measures to ensure patient safety.

  • Monitor liver function: assess baseline enzymes and repeat during therapy.
  • Assess renal function: adjust dosing in patients with impaired clearance.
  • Screen for hepatitis B co‑infection: evaluate risk of flare upon discontinuation.
  • Counsel on adherence: missed doses can lead to resistance development.
  • Avoid use in patients with known hypersensitivity to lamivudine or its excipients.
  • Store at ambient temperature below 25 °C: keep in the original packaging, protect from moisture and light.

Avoid Interactions

Lamivudine can interact with other medicines, influencing efficacy or toxicity.

Major Interactions (Avoid)

  • Didanosine: combined use increases risk of pancreatitis.
  • Stavudine: co‑administration may enhance peripheral neuropathy.
  • Zidovudine: concurrent therapy can augment mitochondrial toxicity.

Moderate Interactions (Monitor Closely)

  • Alcohol: may exacerbate liver toxicity, requiring monitoring.
  • Antacids containing aluminum or magnesium: can affect lamivudine absorption.
  • Nephrotoxic agents: monitor renal function when used together.

Frequently Asked Questions

Lamivudina Mylan contains lamivudine, an antiretroviral medication indicated for the treatment of HIV‑1 infection and for chronic hepatitis B infection. It is used as part of combination therapy for HIV and as monotherapy or in combination for hepatitis B, as prescribed by a qualified healthcare professional.

Lamivudine is a nucleoside analogue that, after conversion to its active triphosphate inside cells, competes with natural nucleotides for incorporation by viral reverse transcriptase or hepatitis B polymerase. Its incorporation halts the elongation of viral DNA, thereby suppressing replication of HIV and hepatitis B viruses.

The dosage of Lamivudina Mylan is individualized by the prescribing clinician based on the patient’s age, weight, renal function, co‑administered drugs, and the specific indication. Only a qualified healthcare professional can set the appropriate dose and regimen.

The safety of lamivudine in pregnancy and lactation has not been definitively established. It should only be used during pregnancy or while breastfeeding when the potential benefit justifies any potential risk, and this decision must be made by the treating physician.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity of Lamivudina Mylan. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Lamivudine belongs to the nucleoside reverse transcriptase inhibitor (NRTI) class, offering a favorable safety profile and convenient oral dosing. Compared with some older NRTIs, it has lower mitochondrial toxicity and is often combined with newer agents such as tenofovir or integrase inhibitors to achieve potent viral suppression.

Lamivudina Mylan should be stored at ambient temperature below 25 °C (77 °F). Keep the tablets in the original container, protect them from moisture and direct light, and ensure they are out of reach of children.

Lamivudina Mylan is administered orally, usually as a tablet taken with or without food. The exact dosing schedule, including frequency and duration, is determined by the prescribing clinician based on the patient’s clinical condition.

Serious risks, though uncommon, include lactic acidosis, severe hepatomegaly with steatosis, and severe skin reactions such as Stevens‑Johnson syndrome or toxic epidermal necrolysis. Patients should be monitored for signs of metabolic disturbance, liver enlargement, or skin changes and seek immediate medical attention if they occur.

Lamivudina Mylan should be avoided in individuals with a known hypersensitivity to lamivudine or any of its excipients. Caution is also advised for patients with severe hepatic impairment, mitochondrial disorders, or those receiving contraindicated drug combinations.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.