Product image of Lamotrigin 1a Pharma (Lamotrigine) supplied by GNH India

Lamotrigin 1a Pharma

Active Ingredient:
Lamotrigine
Origin:
EU

Lamotrigin 1a Pharma (Lamotrigine)

Lamotrigine, the active ingredient in Lamotrigin 1a Pharma, is an anticonvulsant presented as an oral tablet for oral use. It is employed in the management of seizure disorders and mood stabilization in bipolar disorder. It is indicated for patients with focal or generalized seizures and for the long‑term prophylaxis of mood episodes.

GNH India supplies Lamotrigin 1a Pharma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide through regulated channels that ensure product quality and regulatory compliance.

Manufacturer / TM Owner

1a Pharma Gmbh

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Lamotrigine is used in the treatment of seizure disorders and mood disorders, acting on neuronal excitability.
  • Epilepsy: reduces seizure frequency in patients with focal and generalized seizures.
  • Bipolar disorder: stabilizes mood and decreases the risk of depressive and manic episodes.
  • Seizure prophylaxis: provides long‑term control of seizure activity for patients requiring maintenance therapy.

How It Works

  • Lamotrigine inhibits voltage‑gated sodium channels, which stabilizes neuronal membranes and diminishes the release of excitatory neurotransmitters such as glutamate. This reduction in neuronal hyperexcitability underlies its antiepileptic and mood‑stabilizing effects.

Side Effects

Lamotrigine may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Dizziness
  • Headache
  • Nausea
  • Rash
  • Blurred vision
  • Fatigue

Serious or Rare Side Effects

  • Stevens‑Johnson syndrome or toxic epidermal necrolysis
  • Severe skin reactions such as drug reaction with eosinophilia and systemic symptoms (DRESS)
  • Blood dyscrasias including aplastic anemia or agranulocytosis

Precautions & Warnings

  • When prescribing lamotrigine, clinicians should observe several safety considerations.
  • Monitor blood counts: perform regular complete blood count assessments.
  • Assess liver function: schedule periodic liver enzyme testing.
  • Avoid abrupt discontinuation: taper the dose under medical supervision to reduce seizure risk.
  • Use caution in cardiac patients: consider ECG monitoring for conduction abnormalities.
  • Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Lamotrigine interacts with several medicines that can alter its plasma concentration or increase toxicity.

Major Interactions (Avoid)

  • Valproic acid: markedly increases lamotrigine levels, raising risk of severe skin reactions.
  • Carbamazepine: reduces lamotrigine concentrations, potentially diminishing efficacy.
  • Phenytoin: lowers lamotrigine exposure, requiring careful dose adjustment.
  • Oral contraceptives: decrease lamotrigine levels, possibly necessitating dose increase.
  • Enzyme‑inducing antiepileptics: may accelerate lamotrigine clearance.

Moderate Interactions (Monitor Closely)

  • Serotonergic agents: monitor for signs of serotonin syndrome.
  • Other antiepileptic drugs: assess for additive CNS effects.
  • NSAIDs: observe for any increase in lamotrigine-related rash.

Frequently Asked Questions

Lamotrigin 1a Pharma contains lamotrigine, which is prescribed to control seizures in epilepsy and to stabilize mood in patients with bipolar disorder. It is used for both focal and generalized seizure types and for long‑term prophylaxis of depressive or manic episodes.

Lamotrigine works by blocking voltage‑gated sodium channels on neurons, which reduces the excessive firing of nerve cells and limits the release of excitatory neurotransmitters such as glutamate. This action helps to prevent seizure activity and contributes to mood stabilization.

The appropriate dose of lamotrigine is individualized by the prescribing clinician based on the patient’s age, indication, concomitant medications, and renal or hepatic function. Dosage titration is typically gradual to minimise the risk of skin reactions.

Safety data for lamotrigine in pregnancy and lactation are limited. Clinicians weigh the benefits of seizure control or mood stabilization against potential risks to the fetus or infant. Women who are pregnant, planning pregnancy, or breastfeeding should discuss treatment options with their healthcare provider.

To request Lamotrigin 1a Pharma, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Lamotrigine offers a broad spectrum of activity against both focal and generalized seizures and has mood‑stabilizing properties, which distinguishes it from many other antiepileptics that lack psychiatric benefits. Its side‑effect profile is generally favorable, though clinicians monitor for skin reactions more closely than with some alternatives.

Lamotrigin 1a Pharma should be stored at room temperature, below 25 °C, in the original packaging to protect it from moisture and light. Do not store in a bathroom or near heat sources, and keep out of reach of children.

Lamotrigin 1a Pharma is taken orally, usually as a tablet, with or without food. The exact dosing schedule, including the need for titration, is determined by the prescribing physician based on the individual’s therapeutic needs.

The most serious risks include severe skin reactions such as Stevens‑Johnson syndrome or toxic epidermal necrolysis, as well as rare blood disorders like aplastic anemia. Prompt medical attention is required if a rash or signs of infection develop.

Lamotrigine is contraindicated in individuals with a known hypersensitivity to the drug or any of its components. Caution is also advised for patients with a history of severe skin reactions, significant hepatic impairment, or those taking interacting enzyme‑inducing medications without proper dose adjustment.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.