Product image of Lamotrigin Hexal (Lamotrigine) supplied by GNH India

Lamotrigin Hexal

Active Ingredient:
Lamotrigine
Origin:
EU

Lamotrigin Hexal (Lamotrigine)

Lamotrigine, the active ingredient in Lamotrigin Hexal, is an antiepileptic presented as an oral formulation for oral use. It is indicated for the treatment of epilepsy and for mood stabilization in bipolar disorder.

GNH India supplies Lamotrigin Hexal as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Hexal Ag

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Lamotrigine is used in the management of seizure disorders and mood stabilization.

  • Epilepsy (partial seizures): reduces the frequency of focal seizures.
  • Epilepsy (generalized seizures): helps control tonic‑clonic and absence seizures.
  • Bipolar disorder: stabilises mood and reduces the risk of depressive and manic episodes.

How It Works

  • Lamotrigine inhibits voltage‑gated sodium channels, which stabilises neuronal membranes and diminishes the release of excitatory neurotransmitters such as glutamate and aspartate. This reduction in neuronal hyper‑excitability underlies its antiepileptic and mood‑stabilising effects.

Side Effects

Lamotrigin Hexal may be associated with a range of adverse reactions.

Common Side Effects

  • Rash or skin irritation
  • Dizziness or light‑headedness
  • Headache
  • Nausea or gastrointestinal upset
  • Insomnia or sleep disturbances
  • Blurred vision

Serious or Rare Side Effects

  • Stevens‑Johnson syndrome or toxic epidermal necrolysis
  • Severe skin reactions (e.g., maculopapular rash with systemic symptoms)
  • Blood dyscrasias such as agranulocytosis or aplastic anemia
  • Hepatic failure or severe liver injury
  • Suicidal thoughts or behavior
  • Severe hypersensitivity reactions (e.g., anaphylaxis)

Precautions & Warnings

When prescribing Lamotrigin Hexal, clinicians should consider several safety measures.

  • Dose titration: increase gradually to minimise rash risk.
  • Skin monitoring: inspect regularly for any rash or hypersensitivity.
  • Hepatic function: evaluate in patients with liver disease.
  • Renal function: adjust if severe impairment is present.
  • Pregnancy: discuss limited safety data and potential risks.
  • Store at ambient temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Lamotrigine can interact with other medicines, affecting its concentration or safety.

Major Interactions (Avoid)

  • Valproic acid: markedly increases lamotrigine levels, raising toxicity risk.
  • Carbamazepine: reduces lamotrigine concentrations, potentially decreasing efficacy.
  • Phenobarbital: lowers lamotrigine levels, may require dose adjustment.
  • Phenytoin: decreases lamotrigine exposure, affecting seizure control.
  • Oral contraceptives: increase lamotrigine clearance, possibly reducing effectiveness.

Moderate Interactions (Monitor Closely)

  • Serotonergic agents: potential for serotonin syndrome.
  • Other antiepileptics (e.g., gabapentin): may need therapeutic monitoring.
  • Antidepressants (e.g., SSRIs): watch for mood changes.
  • Immunosuppressants: monitor for altered metabolism.
  • Alcohol: may enhance central nervous system depression.

Frequently Asked Questions

Lamotrigin Hexal contains lamotrigine, which is prescribed for the control of epileptic seizures—including partial and generalized types—and for mood stabilization in adults with bipolar disorder. It is used as part of a comprehensive treatment plan under the supervision of a qualified healthcare professional.

Lamotrigine works by blocking voltage‑gated sodium channels on neurons. This action stabilises neuronal membranes and reduces the release of excitatory neurotransmitters such as glutamate, helping to prevent the excessive electrical activity that leads to seizures and mood swings.

The dose of Lamotrigin Hexal is individualized by the prescribing clinician based on the patient’s age, weight, renal and hepatic function, and the specific condition being treated. The prescriber will determine the starting dose and any titration schedule needed to achieve therapeutic effect while minimising side‑effects.

Safety data for lamotrigine in pregnancy are limited, and the medication is classified as pregnancy category unknown. Women who are pregnant, planning pregnancy, or breastfeeding should discuss potential risks and benefits with their healthcare provider, who can weigh seizure control against possible fetal exposure.

To request Lamotrigin Hexal, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Lamotrigin Hexal offers a distinct mechanism—sodium‑channel blockade—different from many older antiepileptics such as carbamazepine or phenytoin. It is often preferred for its relatively favourable cognitive profile and lower risk of certain enzyme‑inducing interactions, though individual response and tolerability vary.

Lamotrigin Hexal should be stored at ambient temperature, below 25 °C, in its original packaging. Keep the product away from moisture, direct sunlight and heat sources to maintain stability and potency throughout its shelf life.

Lamotrigin Hexal is taken orally, usually with or without food, as directed by the prescriber. Tablets should be swallowed whole with a glass of water and not crushed or chewed unless specifically instructed by a healthcare professional.

The most serious risks include severe skin reactions such as Stevens‑Johnson syndrome or toxic epidermal necrolysis, blood dyscrasias, hepatic failure, and the emergence of suicidal thoughts or behaviours. Prompt medical attention is required if any of these symptoms develop.

Lamotrigin Hexal is contraindicated in patients with a known hypersensitivity to lamotrigine or any of its excipients. Caution is also advised for individuals with a history of severe skin reactions, significant liver disease, or those taking interacting medications that could markedly alter lamotrigine levels.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.