Product image of Lamotrigin Orifarm (Lamotrigine) supplied by GNH India

Lamotrigin Orifarm

Active Ingredient:
Lamotrigine
Origin:
EU

Lamotrigin Orifarm (Lamotrigine)

Lamotrigine, the active ingredient in Lamotrigin Orifarm, is an anticonvulsant presented as a tablet for oral use. It is indicated for the treatment of epilepsy, for maintenance therapy in bipolar disorder, and for the prevention of migraine attacks in adult patients, and is widely prescribed worldwide.

GNH India supplies Lamotrigin Orifarm as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company continually adheres to stringent quality standards and provides reliable sourcing for global healthcare providers.

Manufacturer / TM Owner

Orifarm Generics A/S

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Lamotrigin Orifarm (lamotrigine) is used in neurological and psychiatric conditions where abnormal neuronal excitability is a key factor.

  • Epilepsy: reduces seizure frequency and severity in patients with various seizure types.
  • Bipolar disorder: stabilizes mood and prevents recurrence of depressive or manic episodes.
  • Migraine prevention: decreases the frequency of migraine attacks in adults.

How It Works

  • Lamotrigine inhibits voltage‑gated sodium channels, which stabilizes neuronal membranes and diminishes the release of excitatory neurotransmitters such as glutamate. By reducing neuronal hyperexcitability, it helps control seizure activity, mood swings, and migraine generation.

Side Effects

Lamotrigin Orifarm may cause a range of adverse reactions.

Common Side Effects

  • Dizziness: sensation of light‑headedness or unsteadiness.
  • Headache: mild to moderate pain in the head region.
  • Nausea: feeling of stomach upset or urge to vomit.
  • Rash: skin irritation that may appear as redness or small bumps.
  • Blurred vision: temporary visual disturbances.
  • Insomnia: difficulty falling or staying asleep.

Serious or Rare Side Effects

  • Stevens‑Johnson syndrome: severe skin reaction with blistering and mucosal involvement.
  • Toxic epidermal necrolysis: life‑threatening skin detachment.
  • Aseptic meningitis: inflammation of the meninges without bacterial infection.
  • Blood dyscrasias: rare blood disorders such as agranulocytosis.
  • Hepatic failure: severe liver injury requiring medical attention.

Precautions & Warnings

When prescribing Lamotrigin Orifarm, several safety considerations are recommended.

  • Dose titration: increase the dose gradually to lower the risk of rash.
  • Skin reactions: monitor patients closely for any rash, especially during the first weeks of therapy.
  • Hepatic impairment: adjust dosing in patients with liver disease.
  • Concomitant valproate: avoid high‑dose combinations as they markedly raise lamotrigine levels.
  • Pregnancy: use only if the therapeutic benefit outweighs potential risks; data are limited.
  • Store at room temperature: keep below 25°C in the original packaging, protect from moisture.

Avoid Interactions

Lamotrigin Orifarm can interact with several medicines; awareness of major and moderate interactions helps maintain safety.

Major Interactions (Avoid)

  • Valproic acid: markedly increases lamotrigine plasma concentrations.
  • Carbamazepine: reduces lamotrigine levels, potentially decreasing efficacy.
  • Phenobarbital: lowers lamotrigine concentrations, risking loss of seizure control.

Moderate Interactions (Monitor Closely)

  • Oral contraceptives: may lower lamotrigine levels; monitor seizure frequency.
  • Serotonergic agents: combined use can increase the risk of serotonin syndrome.
  • Other antiepileptic drugs: may require dose adjustments based on therapeutic response.

Frequently Asked Questions

Lamotrigin Orifarm contains lamotrigine, an anticonvulsant that is prescribed for the control of seizures in epilepsy, for maintenance therapy in bipolar disorder to prevent mood episodes, and for the prevention of migraine attacks in adult patients.

Lamotrigine works by inhibiting voltage‑gated sodium channels, which stabilizes neuronal membranes and reduces the release of excitatory neurotransmitters such as glutamate. This action lowers neuronal hyperexcitability, helping to control seizures, mood swings, and migraine generation.

The dosage of Lamotrigin Orifarm is individualized. A prescriber determines the starting dose and titration schedule based on the patient’s condition, age, and concomitant medications, following recommended titration guidelines to minimise the risk of rash.

Safety data for lamotrigine in pregnancy are limited. It should be used only if the potential benefit to the mother outweighs any possible risk to the fetus. Breastfeeding is not contraindicated, but the infant may be exposed through milk, so clinical judgment is required.

To order Lamotrigin Orifarm, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and required import documentation.

Compared with older agents such as carbamazepine, lamotrigine has a lower risk of inducing hepatic enzyme changes and fewer drug‑induced hyponatremia. However, it requires careful titration to avoid skin reactions, whereas carbamazepine may cause more frequent dizziness and drug‑interaction issues.

Store Lamotrigin Orifarm tablets at room temperature, below 25 °C, in the original container to protect from moisture and light. Keep the product out of reach of children and do not use if the packaging is damaged.

Lamotrigin Orifarm is taken orally, usually with or without food, as directed by the prescribing clinician. Tablets should be swallowed whole with water and not chewed or crushed unless specifically instructed.

The most serious risks include severe skin reactions such as Stevens‑Johnson syndrome or toxic epidermal necrolysis, aseptic meningitis, blood dyscrasias like agranulocytosis, and rare cases of hepatic failure. Immediate medical attention is required if any of these symptoms appear.

Lamotrigin Orifarm should be avoided in patients with a known hypersensitivity to lamotrigine or any component of the formulation, in those with a history of severe skin reactions to antiepileptic drugs, and in patients where the risk of use outweighs the therapeutic benefit, as judged by a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Lamotrigine

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT