Product image of Lamotrigin Quadro Desitin (Lamotrigine) supplied by GNH India

Lamotrigin Quadro Desitin

Active Ingredient:
Lamotrigine
Origin:
EU

Lamotrigin Quadro Desitin (Lamotrigine)

Lamotrigine, the active ingredient in Lamotrigin Quadro Desitin, is an anticonvulsant presented as an oral dosage form for oral use. It is employed in the management of certain seizure types and as maintenance therapy for bipolar disorder.
GNH India supplies Lamotrigin Quadro Desitin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Desitin Arzneimittel Gmbh

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Indications & Clinical Uses

Lamotrigine acts on neuronal excitability and is indicated for the following conditions:

  • Epilepsy (partial seizures): reduces the frequency and severity of seizure episodes.
  • Bipolar disorder (maintenance therapy): helps prevent mood episode recurrence and stabilises mood over the long term.

How It Works

  • Lamotrigine inhibits voltage‑gated sodium channels, which stabilises neuronal membranes and diminishes the release of excitatory neurotransmitters such as glutamate. By limiting rapid neuronal firing, it reduces the propagation of abnormal electrical activity that underlies seizures and mood instability.

Side Effects

Lamotrigine may cause a range of adverse reactions. The profile includes both frequent, mild events and rare, serious conditions.

Common Side Effects

  • Dizziness
  • Headache
  • Nausea
  • Rash (mild)
  • Insomnia
  • Blurred vision

Serious or Rare Side Effects

  • Stevens‑Johnson syndrome or toxic epidermal necrolysis
  • Severe skin reactions (e.g., bullous eruptions)
  • Blood dyscrasias (e.g., agranulocytosis)
  • Hepatic failure
  • Anaphylactic reactions
  • Severe hypersensitivity reactions

Precautions & Warnings

When prescribing or dispensing lamotrigine, several safety considerations are important.

  • Dose titration: increase gradually as prescribed to minimise rash risk.
  • Monitor skin: watch for any rash, especially during the first weeks of therapy.
  • Avoid abrupt discontinuation: sudden stop may increase seizure frequency.
  • Pregnancy: discuss potential risks with a healthcare professional before use.
  • Renal/hepatic impairment: dose may require adjustment based on organ function.
  • Store at ambient temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Lamotrigine interacts with several medicines; some require avoidance while others need close monitoring.

Major Interactions (Avoid)

  • Valproic acid: can raise lamotrigine plasma levels, increasing toxicity risk.
  • Carbamazepine: may lower lamotrigine levels, reducing efficacy.
  • Oral contraceptives: can enhance lamotrigine clearance, potentially requiring dose adjustment.

Moderate Interactions (Monitor Closely)

  • Phenobarbital or phenytoin: may decrease lamotrigine concentrations.
  • Serotonergic agents: monitor for signs of serotonin syndrome.

Frequently Asked Questions

Lamotrigin Quadro Desitin contains lamotrigine, an anticonvulsant indicated for the treatment of partial seizures in epilepsy and for maintenance therapy in bipolar disorder to help prevent mood episode recurrence.

Lamotrigine blocks voltage‑gated sodium channels on neurons, stabilising the neuronal membrane and reducing the release of excitatory neurotransmitters such as glutamate. This action diminishes abnormal electrical activity that can trigger seizures or mood swings.

The specific dose of lamotrigine is determined by the prescribing clinician based on the patient’s condition, age, renal and hepatic function, and any concomitant medications. Dosage regimens are individualized and should follow the prescriber’s instructions.

Safety of lamotrigine in pregnancy or while breastfeeding is not fully established. Women who are pregnant, planning pregnancy, or nursing should discuss potential risks and benefits with their healthcare provider before starting or continuing therapy.

To order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Lamotrigine is distinguished by its broad spectrum activity against partial seizures and its mood‑stabilising properties, which many older antiepileptics lack. Compared with agents such as carbamazepine, it generally has a lower risk of drug‑induced hyponatremia but may require careful titration to avoid skin reactions.

Lamotrigin Quadro Desitin should be stored at ambient temperature, below 25 °C, in its original packaging. Protect the product from moisture, light, and excessive heat to maintain its stability throughout its shelf life.

The medication is taken orally, usually as a tablet, with or without food as directed by the prescriber. Swallow the tablet whole with a glass of water; do not crush or chew unless specifically instructed.

The most serious risks include severe skin reactions such as Stevens‑Johnson syndrome or toxic epidermal necrolysis, blood dyscrasias, hepatic failure, and anaphylaxis. Prompt medical attention is required if any signs of these reactions appear.

Lamotrigine should be avoided in individuals with a known hypersensitivity to the drug or any of its components, and in patients with a history of severe skin reactions to lamotrigine. Caution is also advised for those with significant hepatic or renal impairment.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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