Product image of Lamotrigin Ratiopharm (Lamotrigine) supplied by GNH India

Lamotrigin Ratiopharm

Active Ingredient:
Lamotrigine
Origin:
EU

Lamotrigin Ratiopharm (Lamotrigine)

Lamotrigine, the active ingredient in Lamotrigin Ratiopharm, is an anticonvulsant presented as an oral tablet for oral use. It is used to treat seizure disorders and as a mood stabiliser in bipolar disorder, helping to reduce seizure frequency and mood swings in adults and children as prescribed.
GNH India supplies Lamotrigin Ratiopharm as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Ratiopharm Gmbh

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Lamotrigin Ratiopharm is indicated for conditions affecting neuronal excitability and mood regulation.

  • Epilepsy: helps control focal and generalized seizure activity.
  • Bipolar disorder: provides maintenance therapy to reduce the frequency of mood episodes.
  • Partial seizures: reduces the occurrence of focal seizures with or without secondary generalisation.

How It Works

  • Lamotrigine inhibits voltage‑gated sodium channels, stabilising neuronal membranes and decreasing the release of excitatory neurotransmitters such as glutamate. This reduction in neuronal hyper‑excitability underlies its effectiveness in preventing seizures and moderating mood fluctuations in bipolar disorder.

Side Effects

Lamotrigin Ratiopharm may cause a range of adverse reactions.

Common Side Effects

  • Dizziness: mild to moderate sensation of light‑headedness.
  • Headache: intermittent or persistent cranial pain.
  • Nausea: occasional stomach upset.
  • Rash: mild skin irritation or erythema.
  • Blurred vision: temporary visual disturbances.
  • Insomnia: difficulty falling or staying asleep.

Serious or Rare Side Effects

  • Stevens‑Johnson syndrome: severe skin reaction requiring immediate medical attention.
  • Toxic epidermal necrolysis: life‑threatening skin detachment.
  • Blood dyscrasias: including agranulocytosis or aplastic anaemia.
  • Hepatic failure: signs of liver dysfunction.
  • Suicidal thoughts: emergence of depressive or suicidal ideation.
  • Severe rash: widespread or bullous eruptions.

Precautions & Warnings

Before initiating Lamotrigin Ratiopharm, several safety considerations are recommended.

  • Dose titration: increase the dose gradually as directed by a prescriber.
  • Monitor blood levels: assess serum concentrations when interacting drugs are co‑administered.
  • Avoid abrupt discontinuation: sudden stop may increase seizure risk.
  • Pregnancy: discuss potential risks and benefits with a healthcare professional.
  • Renal or hepatic impairment: dose may require adjustment based on organ function.
  • Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Lamotrigin Ratiopharm can interact with several medicines, affecting its efficacy or safety.

Major Interactions (Avoid)

  • Valproic acid: markedly increases lamotrigine plasma levels, risking toxicity.
  • Carbamazepine: reduces lamotrigine concentrations, potentially decreasing effectiveness.
  • Phenytoin: accelerates lamotrigine metabolism, lowering therapeutic levels.
  • Oral contraceptives: may lower lamotrigine levels, requiring dose adjustment.
  • Serotonergic agents: combined use may increase risk of serotonin syndrome.

Moderate Interactions (Monitor Closely)

  • Other antiepileptic drugs: may require careful dose titration.
  • SSRIs and SNRIs: monitor for increased side‑effect burden.
  • NSAIDs: may modestly affect lamotrigine clearance.
  • Alcohol: can enhance central nervous system depression.
  • Antihistamines: observe for additive sedation.

Frequently Asked Questions

Lamotrigin Ratiopharm is a prescription medication containing lamotrigine, an anticonvulsant used to control various types of seizures in epilepsy and to provide maintenance therapy for bipolar disorder, helping to stabilise mood and reduce the frequency of depressive or manic episodes.

Lamotrigine works by blocking voltage‑gated sodium channels on neurons, which stabilises the neuronal membrane and reduces the release of excitatory neurotransmitters such as glutamate. This action diminishes neuronal hyper‑excitability, thereby preventing seizure activity and contributing to mood stabilisation in bipolar disorder.

The dosage of Lamotrigin Ratiopharm is individualised and set by the prescribing clinician. Typically, treatment begins with a low dose that is gradually increased according to the patient’s response, tolerance, and any concomitant medications, following established titration guidelines.

Safety of lamotrigine during pregnancy and lactation should be evaluated by a healthcare professional. While some data suggest it can be used when benefits outweigh risks, potential teratogenic effects and neonatal complications require careful monitoring and discussion with the prescriber.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with alternatives such as carbamazepine or valproic acid, lamotrigine generally has a more favourable side‑effect profile, especially regarding weight gain and sedation. However, it requires careful titration and has notable interactions with enzyme‑inducing drugs, which may influence the choice of therapy based on individual patient factors.

Lamotrigin Ratiopharm tablets should be stored at ambient temperature, below 25 °C, in the original packaging to protect them from moisture and light. Keep the product out of reach of children and avoid storing in humid or excessively hot environments.

The medication is taken orally, usually as a whole tablet swallowed with water. It is typically administered once or twice daily, depending on the prescribed regimen, and should be taken at the same times each day to maintain consistent blood levels.

Serious adverse events include severe skin reactions such as Stevens‑Johnson syndrome or toxic epidermal necrolysis, blood dyscrasias like agranulocytosis, hepatic failure, and the emergence of suicidal thoughts or behaviours. Prompt medical attention is required if any of these symptoms occur.

Lamotrigin Ratiopharm is contraindicated in individuals with a known hypersensitivity to lamotrigine or any of its excipients, and should be avoided in patients with severe hepatic impairment or a history of serious skin reactions to the drug. Clinicians must assess each patient’s medical history before prescribing.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Lamotrigine

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT