Product image of Lamotrigin Stada (Lamotrigine) supplied by GNH India

Lamotrigin Stada

Active Ingredient:
Lamotrigine
Origin:
EU

Lamotrigin Stada (Lamotrigine)

Lamotrigine, the active ingredient in Lamotrigin Stada, is an Anticonvulsant presented as an oral formulation for oral use. It is employed in the treatment of epilepsy and as a mood stabiliser in bipolar disorder.

GNH India supplies Lamotrigin Stada as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Stada Arzneimittel Gmbh

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Indications & Clinical Uses

Lamotrigine is an anticonvulsant that acts on neuronal excitability in seizure disorders and mood regulation.

  • Epilepsy (partial seizures): helps control seizure frequency and severity.
  • Generalised tonic‑clonic seizures: reduces the occurrence of convulsive episodes.
  • Bipolar disorder (maintenance therapy): prevents depressive and manic episodes and stabilises mood.

How It Works

  • Lamotrigine inhibits voltage‑gated sodium channels, stabilising neuronal membranes and decreasing the release of excitatory neurotransmitters such as glutamate. This reduction in neuronal firing underlies its efficacy in preventing seizures and mood swings.

Side Effects

Lamotrigine may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Dizziness
  • Headache
  • Nausea
  • Rash or skin irritation
  • Blurred vision
  • Fatigue

Serious or Rare Side Effects

  • Stevens‑Johnson syndrome or toxic epidermal necrolysis
  • Severe skin reactions (e.g., bullous pemphigoid)
  • Blood dyscrasias such as agranulocytosis
  • Hepatic failure
  • Suicidal thoughts or behaviour
  • Severe hypersensitivity reactions

Precautions & Warnings

When prescribing lamotrigine, clinicians should consider several safety measures.

  • Dose titration: increase gradually to minimise rash risk.
  • Skin reactions: monitor for rash and discontinue if severe.
  • Hepatic impairment: adjust dose if liver function is compromised.
  • Renal impairment: monitor renal function and adjust as needed.
  • Pregnancy: discuss potential risks with the prescriber, as safety data are limited.
  • Store at ambient temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Lamotrigine interacts with several medicines that can alter its plasma levels.

Major Interactions (Avoid)

  • Valproate: markedly increases lamotrigine concentrations, raising toxicity risk.
  • Carbamazepine: significantly reduces lamotrigine levels, potentially decreasing efficacy.
  • Phenobarbital: lowers lamotrigine concentrations, possibly leading to breakthrough seizures.

Moderate Interactions (Monitor Closely)

  • Oral contraceptives: may reduce lamotrigine levels; monitor seizure control.
  • Serotonergic agents: watch for signs of serotonin syndrome.
  • Other antiepileptics (e.g., phenytoin): may affect lamotrigine metabolism and require dose adjustments.

Frequently Asked Questions

Lamotrigin Stada contains lamotrigine, which is prescribed for the management of epilepsy, including partial and generalized seizures, and as a maintenance therapy for bipolar disorder to prevent mood episodes.

Lamotrigine blocks voltage‑gated sodium channels on neurons, stabilising their membranes and reducing the release of excitatory neurotransmitters such as glutamate, thereby decreasing seizure activity and mood fluctuations.

The specific dose of Lamotrigin Stada is determined by the prescribing clinician based on the patient’s condition, age, renal and hepatic function, and response to therapy. Dosage regimens are individualized and should follow the prescriber’s instructions.

Safety data for lamotrigine in pregnancy are limited and the product is classified as having an unknown pregnancy category. Women who are pregnant, planning pregnancy, or breastfeeding should discuss potential risks and benefits with their healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Lamotrigine offers a favourable side‑effect profile compared with some older antiepileptics and provides both seizure control and mood‑stabilising benefits, making it a preferred option for patients with co‑existing bipolar disorder. However, drug‑interaction potential and rash risk require careful monitoring.

Lamotrigin Stada should be stored at ambient temperature, below 25 °C, in its original packaging. Keep the product away from moisture, heat and direct sunlight to maintain its stability and potency.

Lamotrigin Stada is taken orally, usually as a tablet, with or without food. The exact administration schedule, including any titration steps, is set by the prescribing clinician to optimise efficacy and minimise adverse effects.

Serious risks include severe skin reactions such as Stevens‑Johnson syndrome or toxic epidermal necrolysis, blood dyscrasias, hepatic failure, and the emergence of suicidal thoughts or behaviours. Prompt medical attention is required if any of these occur.

Lamotrigin Stada is contraindicated in patients with a known hypersensitivity to lamotrigine or any of its excipients. Caution is also advised for individuals with severe hepatic or renal impairment, and it should be avoided in patients taking interacting medications without appropriate monitoring.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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