Product image of Lamotrigin Teva (Lamotrigine) supplied by GNH India

Lamotrigin Teva

Active Ingredient:
Lamotrigine
Origin:
EU

Lamotrigin Teva (Lamotrigine)

Lamotrigine, the active ingredient in Lamotrigin Teva, is a Anticonvulsant presented as an oral tablet for oral use. It treats epilepsy and bipolar disorder in adults and children, helping to control seizures and stabilize mood.

GNH India supplies Lamotrigin Teva as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Teva Sweden Ab

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Indications & Clinical Uses

Lamotrigin Teva is an oral anticonvulsant indicated for several seizure types and mood stabilization in bipolar disorder.

  • Epilepsy: reduces the frequency and severity of partial and generalized seizures.
  • Bipolar disorder: helps prevent manic and depressive episodes and stabilizes mood.
  • Generalized tonic‑clonic seizures: assists in controlling convulsive episodes.

How It Works

  • Lamotrigine inhibits voltage‑gated sodium channels, which stabilizes neuronal membranes and diminishes the release of excitatory neurotransmitters such as glutamate. This reduction in neuronal hyperexcitability underlies its antiepileptic and mood‑stabilizing effects.

Side Effects

Lamotrigin Teva may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Dizziness
  • Headache
  • Nausea
  • Rash (mild)
  • Blurred vision
  • Fatigue

Serious or Rare Side Effects

  • Stevens‑Johnson syndrome or toxic epidermal necrolysis
  • Severe skin reactions (e.g., bullous eruptions)
  • Blood dyscrasias such as agranulocytosis
  • Hepatic failure
  • Suicidal thoughts or behavior
  • Severe hypersensitivity reactions

Precautions & Warnings

Before prescribing Lamotrigin Teva, clinicians should consider several safety measures.

  • Dose titration: increase gradually to lower the risk of rash.
  • Skin reactions: monitor for any rash and discontinue if severe.
  • Hepatic function: assess liver status in patients with hepatic impairment.
  • Pregnancy: risk category unknown; discuss potential benefits and risks with the patient.
  • Drug interactions: review concomitant medications, especially enzyme inducers or inhibitors.
  • Store at below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Lamotrigin Teva can interact with several medicines, requiring careful management.

Major Interactions (Avoid)

  • Valproic acid: raises lamotrigine levels, increasing toxicity risk.
  • Carbamazepine: lowers lamotrigine levels, potentially reducing efficacy.

Moderate Interactions (Monitor Closely)

  • Oral contraceptives: may reduce lamotrigine concentrations; dose adjustment may be needed.
  • Phenobarbital: decreases lamotrigine exposure, requiring monitoring.
  • Rifampin: reduces lamotrigine levels, possibly necessitating dose changes.

Frequently Asked Questions

Lamotrigin Teva contains lamotrigine, an oral anticonvulsant approved for the treatment of epilepsy—including partial, generalized tonic‑clonic, and focal seizures—as well as for maintenance therapy in bipolar disorder to prevent manic and depressive episodes.

Lamotrigine blocks voltage‑gated sodium channels on neurons, stabilising the neuronal membrane and reducing the release of excitatory neurotransmitters such as glutamate. This action diminishes abnormal electrical activity that underlies seizures and mood swings.

The specific dose of Lamotrigin Teva is determined by the prescribing clinician based on the patient’s age, indication, renal and hepatic function, and any concomitant medications. Dose titration is typically gradual to minimise the risk of rash.

Lamotrigine’s safety profile in pregnancy is classified as unknown; it should only be used when the potential benefit outweighs the risk. Limited data suggest low transfer into breast milk, but clinicians should discuss potential risks with the mother before initiating therapy.

To request Lamotrigin Teva, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with carbamazepine, another anticonvulsant, lamotrigine has a lower risk of inducing hepatic enzyme activity and fewer drug‑induced hyponatraemia cases. However, lamotrigine requires slower titration to avoid rash, whereas carbamazepine may cause more dizziness and blood‑count changes.

Lamotrigin Teva tablets should be stored at or below 25 °C, in the original container, protected from moisture and direct sunlight. Keep the product out of reach of children and do not use after the expiry date printed on the packaging.

Lamotrigin Teva is taken orally, usually with or without food, as directed by the prescriber. Tablets should be swallowed whole with a glass of water; crushing or chewing is not recommended unless specifically advised.

The most serious risks include severe skin reactions such as Stevens‑Johnson syndrome or toxic epidermal necrolysis, blood dyscrasias, hepatic failure, and emergence of suicidal thoughts or behaviours. Patients should seek immediate medical attention if they develop a rash, fever, or mood changes.

Lamotrigine is contraindicated in individuals with a known hypersensitivity to lamotrigine or any component of the formulation. Caution is also advised for patients with severe hepatic impairment, a history of serious skin reactions, or those taking interacting enzyme‑inducing antiepileptic drugs without proper dose adjustment.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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