Product image of Lamotrigin Teva (Lamotrigine) supplied by GNH India

Lamotrigin Teva

Active Ingredient:
Lamotrigine
Origin:
EU

Lamotrigin Teva (Lamotrigine)

Lamotrigine, the active ingredient in Lamotrigin Teva, is an anticonvulsant presented as an oral tablet for oral use. It is used to treat various seizure types and as maintenance therapy for bipolar disorder in adults.\n\nGNH India supplies Lamotrigin Teva as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Teva B.V

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Indications & Clinical Uses

  • Lamotrigine is an anticonvulsant that acts on neuronal excitability in seizure disorders and mood stabilization in bipolar disorder.\n\nEpilepsy (partial seizures): reduces the frequency and severity of focal seizures.\nGeneralized seizures: helps control tonic‑clonic and absence seizures.\nBipolar disorder (maintenance therapy): maintains mood stability and lowers the risk of depressive relapse.

How It Works

  • Lamotrigine inhibits voltage‑gated sodium channels, stabilizing neuronal membranes and decreasing the release of excitatory neurotransmitters such as glutamate. This reduction in neuronal firing helps prevent seizure propagation and modulates mood‑regulating pathways, contributing to its antiepileptic and mood‑stabilizing effects.

Side Effects

  • Lamotrigine may cause a range of adverse reactions, from mild to severe.\n\nCommon Side Effects:\n- Dizziness\n- Headache\n- Nausea or vomiting\n- Rash (mild)\n- Blurred vision\n- Fatigue\n\nSerious or Rare Side Effects:\n- Stevens‑Johnson syndrome or toxic epidermal necrolysis\n- Severe skin reactions (e.g., bullous pemphigoid)\n- Blood dyscrasias such as agranulocytosis\n- Hepatic failure\n- Suicidal thoughts or behavior\n- Aseptic meningitis

Precautions & Warnings

  • Before initiating lamotrigine therapy, consider the following precautions.\n\nPregnancy: consult a physician; safety data are limited.\nRenal impairment: dose may require adjustment and monitoring.\nHepatic impairment: monitor liver function tests regularly.\nConcomitant valproic acid: increased risk of severe skin reactions; monitor closely.\nDo not discontinue abruptly: sudden withdrawal may precipitate seizures.\nStore at room temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

  • Lamotrigine interacts with several medicines that can alter its effectiveness or safety.\n\nMajor Interactions (Avoid):\n- Valproic acid: markedly increases lamotrigine levels and risk of skin reactions.\n- Carbamazepine: reduces lamotrigine concentrations, potentially decreasing efficacy.\n- Phenobarbital: lowers lamotrigine levels, requiring dose adjustment.\n\nModerate Interactions (Monitor Closely):\n- Oral contraceptives: may increase lamotrigine clearance, reducing therapeutic effect.\n- Serotonergic agents (e.g., SSRIs, MAOIs): monitor for signs of serotonin syndrome.

Frequently Asked Questions

Lamotrigin Teva contains lamotrigine, which is prescribed to control partial and generalized seizures in epilepsy and to provide maintenance therapy for bipolar disorder, helping to stabilize mood and prevent depressive episodes.

Lamotrigine blocks voltage‑gated sodium channels in neurons, which stabilizes the neuronal membrane and reduces the release of excitatory neurotransmitters such as glutamate. This action diminishes seizure activity and contributes to mood stabilization.

The appropriate dose of lamotrigine is individualized and determined by a qualified prescriber based on the patient’s condition, age, concomitant medications, and renal or hepatic function. Patients should follow the dosing regimen provided by their healthcare professional.

Safety data for lamotrigine during pregnancy and lactation are limited. Women who are pregnant, planning pregnancy, or breastfeeding should discuss potential risks and benefits with their physician to make an informed decision.

To order Lamotrigin Teva, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with carbamazepine, lamotrigine generally has a lower risk of drug‑induced hyponatremia and fewer cognitive side effects, but it requires careful titration to avoid skin reactions. Unlike valproate, lamotrigine is not associated with weight gain or teratogenicity, making it a preferred option for many patients.

Lamotrigine tablets should be stored at room temperature, below 25 °C, in the original packaging to protect them from moisture and light. Keep the product out of reach of children and do not use if the packaging is damaged.

Lamotrigine is taken orally, usually as a tablet that should be swallowed whole with water. It can be taken with or without food, but the dosing schedule should be followed exactly as prescribed to maintain therapeutic levels.

Patients should be alert for severe skin reactions such as Stevens‑Johnson syndrome or toxic epidermal necrolysis, signs of blood disorders like agranulocytosis, liver dysfunction, and any new or worsening mood changes, including suicidal thoughts. Immediate medical attention is required if any of these occur.

Lamotrigine is contraindicated in individuals with a known hypersensitivity to the drug or any of its components, and it should be used with caution in patients with severe hepatic impairment. Those with a history of serious skin reactions to other anticonvulsants should also avoid it.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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