Product image of Lamotrigine Eg (Lamotrigine) supplied by GNH India

Lamotrigine Eg

Active Ingredient:
Lamotrigine
Origin:
EU

Lamotrigine Eg (Lamotrigine)

Lamotrigine, the active ingredient in Lamotrigine Eg, is an anticonvulsant presented as a tablet for oral use. It treats epilepsy and bipolar disorder in adults and children as prescribed.

GNH India supplies Lamotrigine Eg as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Eurogenerics N.V./S.A.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Lamotrigine is used to manage seizure disorders and mood stabilization in bipolar disorder.
  • Epilepsy: reduces the frequency and severity of seizures.
  • Bipolar disorder: helps maintain mood stability and prevents depressive episodes.
  • Adjunct therapy for seizure disorders: can be combined with other antiepileptic drugs to improve seizure control.

How It Works

  • Lamotrigine inhibits voltage‑gated sodium channels, stabilizing neuronal membranes and decreasing the release of excitatory neurotransmitters such as glutamate. This action reduces neuronal hyperexcitability, which underlies its effectiveness in controlling seizures and stabilizing mood in bipolar disorder.

Side Effects

Lamotrigine may cause a range of adverse reactions, from mild to serious.

Common Side Effects

  • Dizziness
  • Headache
  • Nausea or vomiting
  • Blurred vision
  • Insomnia
  • Skin rash

Serious or Rare Side Effects

  • Stevens‑Johnson syndrome or toxic epidermal necrolysis
  • Severe skin reactions (e.g., exfoliative dermatitis)
  • Blood dyscrasias such as agranulocytosis
  • Hepatic failure
  • Suicidal thoughts or behavior
  • Aseptic meningitis

Precautions & Warnings

  • When prescribing lamotrigine, clinicians should consider several safety measures.
  • Monitor blood counts: watch for signs of agranulocytosis or other hematologic abnormalities.
  • Assess liver function: adjust dosing in patients with hepatic impairment.
  • Adjust dose in renal impairment: renal dysfunction may require dose modification.
  • Pregnancy caution: risk category is unknown; use only if benefits outweigh risks.
  • Avoid abrupt discontinuation: taper gradually to reduce seizure recurrence.
  • Store at ambient temperature: keep in the original packaging, protect from moisture and light.

Avoid Interactions

Lamotrigine interacts with several medicines that can alter its plasma levels.

Major Interactions (Avoid)

  • Valproic acid: markedly increases lamotrigine concentrations, raising toxicity risk.
  • Carbamazepine: significantly reduces lamotrigine levels, potentially decreasing efficacy.
  • Phenobarbital: lowers lamotrigine concentrations, requiring dose adjustments.

Moderate Interactions (Monitor Closely)

  • Oral contraceptives: may decrease lamotrigine levels, necessitating monitoring of seizure control.
  • Rifampin: induces metabolism and can reduce lamotrigine exposure.
  • Serotonergic agents: concurrent use may increase the risk of serotonin‑related adverse effects.

Frequently Asked Questions

Lamotrigine Eg is indicated for the treatment of epilepsy, including various seizure types, and for the maintenance therapy of bipolar disorder to help stabilize mood and prevent depressive episodes. It is prescribed by a qualified healthcare professional based on individual patient needs.

Lamotrigine works by blocking voltage‑gated sodium channels on neurons, which stabilizes neuronal membranes and reduces the release of excitatory neurotransmitters such as glutamate. This mechanism diminishes neuronal hyperexcitability, thereby controlling seizures and contributing to mood stabilization in bipolar disorder.

The dosage of Lamotrigine Eg is individualized and determined by the prescribing clinician. Factors such as the specific indication, patient age, weight, renal and hepatic function, and concomitant medications influence the appropriate dose and titration schedule.

The safety of lamotrigine during pregnancy and lactation is not fully established. It should only be used if the potential benefits justify the potential risks to the fetus or infant. Healthcare providers will assess each case and discuss possible alternatives or monitoring strategies.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Lamotrigine offers a broad spectrum of seizure control with a relatively favorable side‑effect profile compared with some older antiepileptics. Unlike enzyme‑inducing agents, it has fewer drug‑interaction concerns, but clinicians must still monitor for interactions with valproic acid, carbamazepine and hormonal contraceptives.

Lamotrigine Eg should be stored at ambient temperature, below 25 °C, in its original packaging. Keep the product away from moisture, heat and direct sunlight to maintain its stability and potency throughout its shelf life.

Lamotrigine Eg is taken orally, usually as a tablet, with or without food as directed by the prescriber. The tablet should be swallowed whole with water and not crushed or chewed unless specifically advised.

The most serious risks include severe skin reactions such as Stevens‑Johnson syndrome or toxic epidermal necrolysis, blood dyscrasias, hepatic failure, and the emergence of suicidal thoughts or behaviors. Patients should seek immediate medical attention if they notice rash, fever, jaundice, or mood changes.

Lamotrigine Eg is contraindicated in individuals with a known hypersensitivity to lamotrigine or any of its excipients. Patients with a history of severe skin reactions to antiepileptic drugs should avoid it, and it should be used with caution in those with significant hepatic or renal impairment.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.