Product image of Lamotrigine Syrimed (Lamotrigine) supplied by GNH India

Lamotrigine Syrimed

Active Ingredient:
Lamotrigine
Origin:
EU

Lamotrigine Syrimed (Lamotrigine)

Lamotrigine, the active ingredient in Lamotrigine Syrimed, is an antiepileptic presented as an oral formulation for oral use. It is prescribed for the treatment of partial seizures, generalized tonic‑clonic seizures, and as maintenance therapy in bipolar disorder, helping to reduce seizure frequency and stabilize mood in affected patients.

GNH India supplies Lamotrigine Syrimed as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with established distribution networks and quality assurance processes that meet EU standards and regulatory compliance.

Manufacturer / TM Owner

Syri Pharma Limited

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Lamotrigine is used to manage seizure disorders and mood stabilization in bipolar disorder.

  • Partial seizures: reduces the frequency of focal onset seizures.
  • Generalized tonic‑clonic seizures: helps prevent convulsive episodes.
  • Bipolar disorder (maintenance therapy): stabilizes mood and decreases risk of manic or depressive episodes.

How It Works

  • Lamotrigine inhibits voltage‑gated sodium channels, which stabilizes neuronal membranes and diminishes the release of excitatory neurotransmitters such as glutamate. By reducing neuronal hyper‑excitability, it helps control abnormal electrical activity associated with seizures and mood swings.

Side Effects

Lamotrigine may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Dizziness: sensation of light‑headedness or unsteadiness.
  • Headache: mild to moderate pain in the head region.
  • Nausea: feeling of queasiness or urge to vomit.
  • Rash: skin redness or irritation, often mild.

Serious or Rare Side Effects

  • Stevens‑Johnson syndrome: severe skin reaction with blistering and detachment.
  • Toxic epidermal necrolysis: life‑threatening skin loss.
  • Blood dyscrasias: abnormal blood counts such as agranulocytosis.
  • Hepatic failure: impaired liver function.
  • Suicidal thoughts: emergence of depressive or suicidal ideation.

Precautions & Warnings

Before initiating therapy, several safety considerations should be reviewed.

  • Renal or hepatic impairment: adjust dose as needed and monitor function.
  • Pregnancy: discuss potential risks with the prescriber; data are limited.
  • Concomitant valproate: increased risk of severe skin reactions; use with caution.
  • History of rash: avoid use if patient previously experienced hypersensitivity.
  • Store at ambient temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Lamotrigine can interact with other medicines, altering its effectiveness or safety.

Major Interactions (Avoid)

  • Valproate: markedly increases lamotrigine plasma levels, raising toxicity risk.
  • Carbamazepine: induces metabolism, reducing lamotrigine concentrations.
  • Phenytoin: enzyme induction leading to lower lamotrigine exposure.
  • Oral contraceptives: increase lamotrigine clearance, potentially decreasing efficacy.

Moderate Interactions (Monitor Closely)

  • Serotonergic agents: may increase risk of serotonin syndrome.
  • Other antiepileptics (e.g., phenobarbital): require dose adjustments.
  • NSAIDs (e.g., ibuprofen): can raise lamotrigine levels modestly.

Frequently Asked Questions

Lamotrigine Syrimed is prescribed for partial (focal) seizures, generalized tonic‑clonic seizures, and as a maintenance therapy for bipolar disorder. In each case, the medication helps to lower the frequency of seizures or stabilize mood, providing clinical benefit for patients with these neurological or psychiatric conditions.

Lamotrigine works by blocking voltage‑gated sodium channels on neurons, which stabilises the neuronal membrane and reduces the release of excitatory neurotransmitters such as glutamate. This action diminishes abnormal electrical activity that underlies seizures and mood disturbances, contributing to seizure control and mood stabilization.

The specific dose of Lamotrigine Syrimed is determined by the prescribing clinician based on the patient’s age, weight, renal and hepatic function, and the condition being treated. Dosage titration follows established clinical guidelines, and patients should follow the prescriber’s instructions without deviation.

Safety data for lamotrigine in pregnancy and lactation are limited. Healthcare providers weigh potential benefits against possible risks to the fetus or infant. Women who are pregnant, planning pregnancy, or breastfeeding should discuss individual circumstances with their prescriber before starting or continuing therapy.

To request Lamotrigine Syrimed, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Lamotrigine is distinguished by its broad spectrum activity against both focal and generalized seizures and its mood‑stabilizing properties, which many other antiepileptics lack. Compared with older agents such as carbamazepine, lamotrigine generally has a lower risk of drug‑induced hyponatremia but may carry a higher risk of skin reactions, especially when combined with valproate.

Lamotrigine Syrimed should be stored at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain stability throughout its shelf life.

Lamotrigine Syrimed is taken orally, usually with or without food, as directed by the prescriber. The tablets (or oral formulation) should be swallowed whole with a glass of water and not crushed or chewed unless specifically instructed by a healthcare professional.

The most serious risks include severe skin reactions such as Stevens‑Johnson syndrome or toxic epidermal necrolysis, blood dyscrasias like agranulocytosis, hepatic failure, and the emergence of suicidal thoughts or behavior. Patients should seek immediate medical attention if they notice rash, fever, flu‑like symptoms, or changes in mood.

Lamotrigine Syrimed is contraindicated in individuals with a known hypersensitivity to lamotrigine or any of its excipients. Patients with a history of severe skin reactions to antiepileptic drugs should avoid it, and those with significant hepatic or renal impairment require careful evaluation before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.