Product image of Lamotrigine Viatris (Lamotrigine) supplied by GNH India

Lamotrigine Viatris

Active Ingredient:
Lamotrigine
Origin:
EU

Lamotrigine Viatris (Lamotrigine)

Lamotrigine, the active ingredient in Lamotrigine Viatris, is an anticonvulsant presented as an oral tablet for oral use. It is employed to treat various seizure types and to provide maintenance therapy in bipolar disorder.

GNH India supplies Lamotrigine Viatris as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable logistics for global distribution. Clients benefit from consistent product availability, regulatory support, and responsive technical assistance throughout the supply chain.

Manufacturer / TM Owner

Viatris Sante

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Indications & Clinical Uses

  • Lamotrigine is an anticonvulsant that acts on neuronal excitability to control seizure activity and stabilize mood.
  • Partial seizures: reduces seizure frequency in focal onset epilepsy.
  • Generalized tonic‑clonic seizures: decreases occurrence of convulsive seizures.
  • Bipolar disorder: maintenance therapy to prevent recurrence of mood episodes.
  • Seizure prophylaxis: used as adjunct therapy to lower overall seizure burden.

How It Works

  • Lamotrigine inhibits voltage‑gated sodium channels, stabilising neuronal membranes and diminishing the release of excitatory neurotransmitters such as glutamate. This reduction in neuronal hyper‑excitability underlies its effectiveness in preventing seizures and in moderating mood swings in bipolar disorder.

Side Effects

Lamotrigine may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Dizziness
  • Headache
  • Nausea
  • Mild skin rash

Serious or Rare Side Effects

  • Stevens‑Johnson syndrome or toxic epidermal necrolysis
  • Aseptic meningitis
  • Blood dyscrasias such as agranulocytosis

Precautions & Warnings

  • When prescribing lamotrigine, several safety considerations should be observed to minimize risk.
  • Pregnancy: limited data; use only if benefit outweighs risk.
  • Renal impairment: monitor renal function and adjust dose if necessary.
  • Hepatic impairment: use caution and consider dose modification.
  • Concomitant valproate: may increase lamotrigine levels; monitor closely.
  • Discontinuation: avoid abrupt stopping to prevent seizure recurrence.
  • Store at ambient temperature below 25°C: keep in original packaging, protect from moisture.

Avoid Interactions

Lamotrigine interacts with several medicines, requiring attention to avoid altered drug exposure.

Major Interactions (Avoid)

  • Valproic acid: markedly increases lamotrigine concentrations, risk of toxicity.
  • Carbamazepine: reduces lamotrigine levels, may diminish efficacy.
  • Phenobarbital: lowers lamotrigine concentrations, may require dose increase.

Moderate Interactions (Monitor Closely)

  • Oral contraceptives: decrease lamotrigine levels, may need dose adjustment.
  • Serotonergic agents: potential for serotonin syndrome, monitor symptoms.
  • Other antiepileptics (e.g., phenytoin): may reduce lamotrigine exposure.

Frequently Asked Questions

Lamotrigine Viatris is prescribed to control partial and generalized tonic‑clonic seizures in patients with epilepsy and as a maintenance therapy to prevent mood episode recurrence in individuals with bipolar disorder.

Lamotrigine blocks voltage‑gated sodium channels on neurons, which stabilises the neuronal membrane and reduces the release of excitatory neurotransmitters such as glutamate, thereby decreasing seizure activity and mood instability.

The dosage of Lamotrigine Viatris is determined by the prescribing clinician based on the patient’s condition, age, renal and hepatic function, and any concomitant medications. Patients should follow the prescriber’s specific instructions.

Safety data for lamotrigine in pregnancy and lactation are limited. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and the decision should be made in consultation with a healthcare professional.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Lamotrigine offers a broad spectrum of seizure control and mood‑stabilising properties, with a relatively favourable side‑effect profile compared with some older anticonvulsants. However, drug‑specific factors such as interaction potential, individual tolerability and therapeutic goals influence the choice of therapy.

Lamotrigine Viatris should be stored at ambient temperature below 25 °C, in its original packaging, and protected from moisture and direct sunlight to maintain product stability.

Lamotrigine Viatris is taken orally, usually as a tablet, with or without food as directed by the prescriber. The tablet should be swallowed whole with water and not crushed or chewed unless specifically instructed.

Serious risks include severe skin reactions such as Stevens‑Johnson syndrome or toxic epidermal necrolysis, aseptic meningitis, and blood dyscrasias like agranulocytosis. Prompt medical attention is required if any signs of these conditions appear.

Lamotrigine Viatris is contraindicated in patients with a known hypersensitivity to lamotrigine or any component of the formulation. Caution is also advised for individuals with severe hepatic or renal impairment, and those taking interacting medications without appropriate monitoring.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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