Product image of Lamsil (Terbinafine Hydrochloride) supplied by GNH India

Lamsil

Active Ingredient:
Terbinafine Hydrochloride
Origin:
EU

Lamsil (Terbinafine Hydrochloride)

Terbinafine, the active ingredient in Lamsil, is a allylamine antifungal presented as a topical formulation for skin use. It treats dermatophyte infections such as athlete's foot, ringworm and jock itch in adults and children.\n\nGNH India supplies Lamsil as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Karo Healthcare Ab

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Indications & Clinical Uses

  • Terbinafine is an allylamine antifungal used to treat superficial fungal infections of the skin.\n\nTinea corporis: reduces the fungal load and clears the ring‑shaped rash.\nTinea pedis: alleviates itching and scaling on the feet.\nTinea cruris: resolves redness and irritation in the groin area.

How It Works

  • Terbinafine inhibits the fungal enzyme squalene epoxidase, which blocks the conversion of squalene to ergosterol. This disruption impairs the synthesis of ergosterol, an essential component of fungal cell membranes, leading to accumulation of toxic squalene and ultimately causing fungal cell death.

Side Effects

  • Terbinafine is generally well tolerated when applied to intact skin, but local reactions may occur.\n\nCommon Side Effects:\n- Burning sensation at the application site\n- Itching or pruritus\n- Redness or erythema\n- Dryness or scaling of the skin\n- Mild irritation or stinging\n- Peeling of the treated area\n\nSerious or Rare Side Effects:\n- Allergic contact dermatitis\n- Severe skin reactions such as Stevens‑Johnson syndrome\n- Urticaria or hives\n- Angioedema\n- Systemic absorption leading to liver enzyme elevation\n- Unexplained fever or malaise

Precautions & Warnings

  • Before using Lamsil, consider the following safety measures.\n\nPregnancy: consult a healthcare professional; safety not established.\nBreastfeeding: avoid application on broken skin; seek medical advice.\nAge: not recommended for children under 2 years unless directed by a clinician.\nConcurrent topical antifungals: avoid overlapping applications to reduce irritation risk.\nOpen wounds or mucous membranes: do not apply to these areas.\nStore at room temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

  • Terbinafine applied topically has limited systemic interactions, but caution is advised with certain co‑administered agents.\n\nMajor Interactions (Avoid):\n- Systemic antifungals (e.g., itraconazole): may increase systemic exposure if large skin areas are treated.\n- Strong CYP450 inhibitors: avoid extensive use to prevent potential systemic accumulation.\n\nModerate Interactions (Monitor Closely):\n- Alcohol consumption: monitor for rare liver effects with extensive absorption.\n- Other topical medications: may increase local irritation when combined.\n- Phototherapy: observe for heightened skin sensitivity.

Frequently Asked Questions

Lamsil contains terbinafine and is indicated for the topical treatment of dermatophyte infections such as athlete's foot (tinea pedis), ringworm (tinea corporis) and jock itch (tinea cruris). It works by eliminating the fungi that cause these superficial skin conditions.

Terbinafine blocks the fungal enzyme squalene epoxidase, preventing the synthesis of ergosterol, a vital component of fungal cell membranes. This leads to an accumulation of squalene, which is toxic to the fungus, ultimately causing fungal cell death and clearing the infection.

The dosing regimen for Lamsil is determined by the prescribing healthcare professional based on the infection type, location and patient characteristics. Patients should follow the specific instructions provided by their clinician or the product label.

Safety of topical terbinafine during pregnancy has not been established, so pregnant individuals should consult their healthcare provider before use. While limited systemic absorption occurs, breastfeeding mothers should avoid applying Lamsil to broken skin and seek medical advice.

To order Lamsil, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with azole antifungals, terbinafine has a different mechanism—squalene epoxidase inhibition—and often achieves faster clinical cure rates for dermatophyte infections. It is available over‑the‑counter in many regions, whereas some alternatives may require a prescription.

Lamsil should be stored at room temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed when not in use.

Apply a thin layer of Lamsil to the affected skin area once or twice daily, as directed by the prescriber. Gently rub the cream into clean, dry skin and wash hands after application to avoid accidental contact with eyes or mucous membranes.

Although rare, serious adverse reactions can include allergic contact dermatitis, severe skin reactions such as Stevens‑Johnson syndrome, urticaria, angioedema, and, in exceptional cases, liver enzyme elevations due to systemic absorption. Seek immediate medical attention if any of these occur.

Lamsil should not be used on broken skin, mucous membranes, or in individuals with a known hypersensitivity to terbinafine or any formulation component. Children under two years of age should avoid use unless specifically advised by a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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