Product image of Lanadut (Dutasteride) supplied by GNH India

Lanadut

Active Ingredient:
Dutasteride
Origin:
EU

Lanadut (Dutasteride)

Dutasteride, the active ingredient in Lanadut, is a 5-alpha-reductase inhibitor presented as an oral dosage form for oral use. It treats benign prostatic hyperplasia in men and is also employed off‑label for male pattern hair loss.

GNH India supplies Lanadut as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

G.L. Pharma Gmbh

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Indications & Clinical Uses

Dutasteride acts on the hormonal pathway that drives prostate enlargement and androgen‑related hair loss.

  • Benign prostatic hyperplasia (BPH): reduces prostate volume and improves urinary flow in men.
  • Male pattern hair loss (off‑label): may slow hair thinning and promote regrowth of scalp hair.

How It Works

  • Dutasteride inhibits both type I and type II 5‑alpha‑reductase enzymes, decreasing the conversion of testosterone to the more potent androgen dihydrotestosterone (DHT). Lower DHT levels lead to reduced stimulation of androgen‑dependent tissues such as the prostate and scalp hair follicles, thereby mitigating prostate enlargement and hair loss progression.

Side Effects

Adverse reactions may vary in frequency and severity.

Common Side Effects

  • Decreased libido: reduced sexual desire.
  • Erectile dysfunction: difficulty achieving or maintaining an erection.
  • Ejaculation disorders: decreased volume or pain.
  • Breast tenderness or enlargement: mild swelling of male breast tissue.
  • Decreased semen volume: reduced ejaculate amount.
  • Headache: mild to moderate head pain.

Serious or Rare Side Effects

  • Allergic reactions: rash, itching, swelling, or anaphylaxis.
  • Breast cancer: rare occurrence of malignant breast tissue.
  • Liver enzyme elevation: signs of hepatic dysfunction.
  • Severe hypotension: marked drop in blood pressure, especially when combined with certain antihypertensives.
  • Persistent sexual dysfunction: lasting loss of sexual function after discontinuation.

Precautions & Warnings

Patients should be aware of several safety considerations before starting therapy.

  • Monitor PSA levels: regular testing to assess prostate health.
  • Evaluate liver function: baseline and periodic liver enzyme checks.
  • Avoid use in women of childbearing potential: contraindicated due to teratogenic risk.
  • Assess cardiovascular status: caution in patients with low blood pressure.
  • Counsel about potential sexual side effects: discuss possible changes in libido and erectile function.
  • Store at room temperature: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Dutasteride may interact with other medicines, requiring careful management.

Major Interactions (Avoid)

  • Strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole): may increase dutasteride exposure.
  • Alpha‑blockers (e.g., tamsulosin): combined use can cause symptomatic hypotension.
  • Warfarin: potential increase in INR and bleeding risk.

Moderate Interactions (Monitor Closely)

  • CYP3A4 inducers (e.g., rifampin, phenytoin): may reduce dutasteride effectiveness.
  • Other 5‑alpha‑reductase inhibitors (e.g., finasteride): additive hormonal effects.
  • Antiplatelet agents (e.g., aspirin, clopidogrel): monitor for enhanced bleeding tendency.

Frequently Asked Questions

Lanadut contains dutasteride, which is approved for the treatment of benign prostatic hyperplasia (BPH) in adult men. It helps shrink an enlarged prostate and improve urinary symptoms. In some regions it is also prescribed off‑label to slow male pattern hair loss, although this use is not formally approved.

Dutasteride blocks both type I and type II 5‑alpha‑reductase enzymes, the proteins that convert testosterone into dihydrotestosterone (DHT). By lowering DHT levels, the drug reduces androgen‑driven growth of prostate tissue and diminishes the hormonal stimulus that contributes to male pattern hair loss.

The exact dosage of Lanadut is determined by the prescribing clinician based on the patient’s condition, age, renal and hepatic function, and other individual factors. Healthcare professionals follow local prescribing guidelines and adjust the dose as needed; patients should follow the prescriber’s instructions precisely.

Dutasteride is classified as Pregnancy Category X, meaning it is contraindicated in women who are pregnant or may become pregnant because it can cause fetal harm. It is also not recommended for breastfeeding mothers, as it may be excreted in breast milk and affect a nursing infant.

To request Lanadut, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.

Both dutasteride and finasteride inhibit 5‑alpha‑reductase, but dutasteride blocks both type I and type II isoenzymes, offering a more comprehensive reduction of DHT. Consequently, dutasteride generally produces a greater decrease in prostate volume and may be more effective for severe BPH, while finasteride is often used for milder cases and has a longer market history.

Lanadut should be stored at room temperature, below 25 °C, in its original container to protect it from moisture and light. Keep the product out of reach of children and avoid storing it in bathrooms or other humid environments.

Lanadut is taken orally, usually once daily, with or without food. The tablet should be swallowed whole with a glass of water and not chewed or crushed, unless otherwise directed by a healthcare professional.

Serious but rare risks include severe allergic reactions such as rash, swelling, or anaphylaxis; the development of male breast cancer; and significant liver enzyme elevations indicating possible hepatic injury. Patients should seek immediate medical attention if they notice any signs of these conditions.

Lanadut should not be used by women, especially those who are pregnant, planning to become pregnant, or breastfeeding. It is also contraindicated in children and adolescents, and in men with known hypersensitivity to dutasteride or any of the tablet’s excipients.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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