Product image of Lanciprol (Lansoprazole) supplied by GNH India

Lanciprol

Active Ingredient:
Lansoprazole
Origin:
EU

Lanciprol (Lansoprazole)

Lansoprazole, the active ingredient in Lanciprol, is a proton pump inhibitor presented as an oral tablet for oral use. It reduces gastric acid production and is used to treat conditions such as gastro‑oesophageal reflux disease, peptic ulcer disease, Helicobacter pylori infection and erosive esophagitis.

GNH India supplies Lanciprol as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory documentation for export markets. Customers benefit from reliable lead times and comprehensive after‑sales support.

Manufacturer / TM Owner

Sja Pharm Ltd

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Indications & Clinical Uses

Lansoprazole is indicated for several gastrointestinal acid‑related conditions.

  • Gastro‑oesophageal reflux disease (GERD): reduces acid exposure, relieving heartburn and promoting healing of the esophageal lining.
  • Peptic ulcer disease: promotes ulcer healing by decreasing gastric acidity.
  • Helicobacter pylori eradication: used in combination therapy to increase eradication rates.
  • Erosive esophagitis: facilitates mucosal repair by maintaining a higher gastric pH.

How It Works

  • Lansoprazole selectively and irreversibly inhibits the H⁺/K⁺‑ATPase enzyme (the gastric proton pump) on the secretory surface of parietal cells. By blocking this final step of acid secretion, it markedly lowers both basal and stimulated gastric acid output, allowing the gastric environment to become less acidic and supporting the healing of acid‑related lesions. The inhibition persists until new pumps are synthesized, providing prolonged acid suppression over 24 hours.

Side Effects

Lansoprazole may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Headache: mild to moderate intensity.
  • Diarrhea: watery stools, usually self‑limiting.
  • Nausea: occasional feeling of stomach upset.
  • Abdominal pain: cramping or discomfort in the stomach area.

Serious or Rare Side Effects

  • Clostridioides difficile infection: severe colitis presenting with watery diarrhea and abdominal pain.
  • Interstitial nephritis: kidney inflammation causing reduced urine output and flank pain.
  • Stevens‑Johnson syndrome: rare skin reaction with blistering and mucosal involvement.
  • Hepatic injury: elevated liver enzymes or jaundice.

Precautions & Warnings

Before prescribing Lansoprazole, clinicians should consider several safety and handling precautions.

  • Assess renal function: dose adjustment may be required in severe impairment.
  • Review concomitant medications: potential interactions can affect efficacy or safety.
  • Monitor for osteoporosis: long‑term use may reduce calcium absorption.
  • Use caution in pregnancy: limited data, prescribe only if benefit outweighs risk.
  • Store at ambient temperature: keep below 25 °C, protect from moisture and light in original container.

Avoid Interactions

Lansoprazole can alter the plasma concentrations of several drugs, requiring attention to interaction risk.

Major Interactions (Avoid)

  • Clopidogrel: reduced antiplatelet effect, may increase cardiovascular events.
  • Atazanavir (and other protease inhibitors): decreased absorption, loss of antiviral efficacy.
  • Ketoconazole and other azole antifungals: markedly reduced bioavailability.

Moderate Interactions (Monitor Closely)

  • Warfarin: enhanced anticoagulant effect, monitor INR.
  • Digoxin: increased serum levels, observe for toxicity.
  • Methotrexate (high dose): reduced renal clearance, watch for toxicity.

Frequently Asked Questions

Lanciprol contains the active ingredient lansoprazole, which is prescribed to lower stomach acid. It is commonly used to manage gastro‑oesophageal reflux disease, heal peptic ulcers, assist in Helicobacter pylori eradication regimens, and treat erosive esophagitis by maintaining a less acidic gastric environment.

Lansoprazole belongs to the proton pump inhibitor class. It binds irreversibly to the H⁺/K⁺‑ATPase enzyme on gastric parietal cells, blocking the final step of acid secretion. This results in a sustained reduction of gastric acidity, allowing damaged mucosa to heal and reducing symptoms caused by excess acid.

The appropriate dose of Lanciprol is determined by the prescribing healthcare professional based on the specific condition, severity, and patient characteristics. Dosage recommendations are provided in the product label, and the prescriber will tailor the regimen to each individual’s therapeutic needs.

Safety data for lansoprazole in pregnancy and lactation are limited. It should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant. Healthcare providers will evaluate the risk‑benefit profile before prescribing it to pregnant or nursing patients.

To request Lanciprol, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.

Lanciprol (lansoprazole) and omeprazole belong to the same drug class and share a similar mechanism of action. Differences lie in pharmacokinetic profiles; lansoprazole often achieves a slightly faster onset of acid suppression and may have a marginally longer half‑life, which can influence dosing frequency and individual patient response.

Lanciprol tablets should be stored at ambient temperature, preferably below 25 °C. Keep them in the original packaging to protect from moisture and light. Do not store in bathrooms or near heat sources, and keep out of reach of children.

Lanciprol is taken orally, usually as a whole tablet with a glass of water. It is commonly recommended to take the dose before a meal, often in the morning, but the exact timing should follow the prescriber’s instructions to achieve optimal acid control.

Serious but rare adverse events include Clostridioides difficile‑associated colitis, interstitial nephritis, severe liver injury, and hypersensitivity reactions such as Stevens‑Johnson syndrome. Patients should seek immediate medical attention if they experience persistent diarrhea, rash, jaundice, or unexplained kidney‑related symptoms.

Lanciprol is contraindicated in individuals with known hypersensitivity to lansoprazole or any component of the formulation. Caution is advised for patients with severe liver disease, those taking certain interacting medications such as clopidogrel, and patients with a history of osteoporosis when long‑term therapy is considered.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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