Product image of Lanicor (Digoxin) supplied by GNH India

Lanicor

Active Ingredient:
Digoxin
Origin:
EU

Lanicor (Digoxin)

Digoxin, the active ingredient in Lanicor, is a cardiac glycoside presented as an oral tablet for oral use. It is employed in the management of heart failure and certain cardiac arrhythmias, particularly in adult patients where rate control is required. The drug acts by enhancing myocardial contractility while modulating electrical conduction through the atrioventricular node.

GNH India supplies Lanicor as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Teofarma S.R.L.

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Indications & Clinical Uses

Digoxin is used in cardiovascular conditions that benefit from increased contractility and slowed atrioventricular conduction.

  • Heart failure: improves cardiac output and reduces symptoms of congestion.
  • Atrial fibrillation: controls ventricular rate by decreasing AV nodal conduction.
  • Atrial flutter: assists in rate control when other therapies are unsuitable.

How It Works

  • Digoxin inhibits the Na⁺/K⁺‑ATPase pump on cardiac myocytes, leading to an increase in intracellular sodium. This alteration reduces the activity of the sodium‑calcium exchanger, causing calcium accumulation within the cell, which enhances myocardial contractility. Concurrently, digoxin augments vagal tone, slowing conduction through the atrioventricular node and thereby reducing heart rate in atrial arrhythmias.

Side Effects

Adverse reactions to digoxin can vary in frequency and severity.

Common Side Effects

  • Nausea: mild gastrointestinal upset.
  • Vomiting: occasional emesis.
  • Diarrhea: loose stools.
  • Fatigue: reduced energy levels.
  • Blurred vision: transient visual disturbances.
  • Dizziness: light‑headed sensation.

Serious or Rare Side Effects

  • Cardiac arrhythmias: potentially life‑threatening rhythm disturbances.
  • Severe bradycardia: markedly slowed heart rate.
  • Heart block: impaired electrical conduction.
  • Hyperkalemia: elevated serum potassium.
  • Visual halos: yellow‑green color perception.
  • Confusion: altered mental status.

Precautions & Warnings

When prescribing digoxin, clinicians should consider several safety measures.

  • Monitor serum digoxin levels: ensure therapeutic range is maintained.
  • Adjust dose in renal impairment: reduce dosage for decreased clearance.
  • Caution with electrolyte disturbances: correct hypokalemia or hypermagnesemia.
  • Avoid in known hypersensitivity: discontinue if allergic reaction occurs.
  • Use with caution in pregnancy: limited data, assess risk‑benefit.
  • Store at room temperature: keep in original container, protect from moisture.

Avoid Interactions

Digoxin interacts with several medications that can alter its plasma concentration or cardiac effects.

Major Interactions (Avoid)

  • Amiodarone: markedly increases digoxin levels.
  • Quinidine: raises digoxin concentration and risk of toxicity.
  • Verapamil: enhances digoxin effect on AV node.

Moderate Interactions (Monitor Closely)

  • Spironolactone: may increase digoxin levels.
  • Diuretics (especially thiazides): affect electrolyte balance influencing toxicity.
  • Erythromycin: can elevate digoxin concentrations modestly.

Frequently Asked Questions

Lanicor contains digoxin, which is prescribed to improve cardiac contractility in patients with heart failure and to control ventricular rate in atrial fibrillation or atrial flutter by slowing atrioventricular nodal conduction.

Digoxin blocks the Na⁺/K⁺‑ATPase pump on heart muscle cells, leading to increased intracellular calcium that strengthens contractions. It also enhances vagal tone, reducing the speed of electrical signals through the AV node, which helps control rapid heart rhythms.

The appropriate dose of Lanicor is individualized by the prescribing clinician based on factors such as age, kidney function, and serum digoxin concentration. Patients should follow the exact regimen provided by their healthcare professional.

Safety data for digoxin in pregnancy and lactation are limited. It should only be used when the potential benefit justifies any possible risk to the fetus or infant, and the decision must be made by a qualified healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Unlike ACE inhibitors or beta‑blockers, digoxin primarily increases contractile force and slows AV nodal conduction. It is often added to standard therapy when additional symptom control is needed, especially in patients with reduced ejection fraction and persistent arrhythmias.

Lanicor should be stored at room temperature, below 25 °C, in its original packaging. Keep the product away from moisture and direct sunlight to maintain stability and potency.

Lanicor is taken orally, usually with or without food, as directed by the prescriber. The tablet should be swallowed whole with a glass of water and not chewed or crushed unless specifically instructed.

The most critical risks include cardiac arrhythmias such as ventricular tachycardia, severe bradycardia, heart block, and digoxin toxicity manifested by nausea, visual disturbances, and electrolyte abnormalities. Prompt medical attention is required if these symptoms occur.

Lanicor is contraindicated in patients with known hypersensitivity to digoxin, ventricular fibrillation, or those with uncontrolled ventricular tachyarrhythmias. Caution is also advised for individuals with severe renal impairment or significant electrolyte imbalances.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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