Lanoxin 250 (Digoxin)

Digoxin inhibits the Na⁺/K⁺‑ATPase pump on heart cells, leading to increased intracellular sodium. This change reduces calcium extrusion, raising intracellular calcium levels, which strengthens heart muscle contraction. Additionally, digoxin enhances vagal tone, slowing atrioventricular nodal conduction and helping control rapid heart rhythms.

The appropriate dose of Lanoxin 250 is determined by the prescribing clinician based on the patient’s age, renal function, electrolyte status and therapeutic response. Dosage adjustments are made to achieve target serum digoxin concentrations while minimizing toxicity.

Lanoxin 250 is classified as Pregnancy Category C, meaning risk to the fetus cannot be ruled out. It should only be used when the potential maternal benefit outweighs possible risks. Limited data are available for breastfeeding; the decision should be made by a healthcare professional.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Unlike diuretics or ACE inhibitors that primarily reduce fluid overload or blood pressure, digoxin directly increases myocardial contractility and modulates heart rate. It is often used as an adjunct to standard therapy, especially when rate control in atrial fibrillation is needed, whereas other agents may not provide this dual action.

Lanoxin 250 tablets should be stored at ambient temperature, below 25 °C, in their original packaging. Protect the tablets from moisture and direct sunlight to maintain potency throughout the shelf life.

Lanoxin 250 is taken orally, usually with or without food, as directed by a healthcare professional. The tablet should be swallowed whole with a glass of water. Patients should follow the prescribed schedule and not alter the dose without medical advice.

The most serious risks include digoxin toxicity, which can manifest as severe arrhythmias, bradycardia, heart block, hyperkalemia, and visual disturbances such as colored halos. Prompt medical attention is required if symptoms of toxicity appear.

Lanoxin 250 should be avoided in patients with known hypersensitivity to digoxin, severe ventricular arrhythmias, advanced atrioventricular block without a pacemaker, and in those with uncontrolled electrolyte imbalances. Clinicians must assess each individual’s medical history before prescribing.