Lanoxin (Digoxin)

Digoxin inhibits the sodium‑potassium ATPase enzyme on cardiac cells, causing an increase in intracellular sodium. This change reduces the activity of the sodium‑calcium exchanger, leading to higher calcium levels inside the heart muscle cells, which strengthens contractions. It also enhances vagal tone, slowing electrical conduction through the atrioventricular node and helping to control heart rate.

The appropriate dose of Lanoxin is individualized by the prescribing clinician based on factors such as the patient’s age, kidney function, body weight, and severity of the cardiac condition. Only a qualified healthcare professional should determine the exact regimen and any dose adjustments.

Lanoxin is classified as Pregnancy Category C, meaning risk to the fetus cannot be ruled out. It should be used only when the potential benefit justifies the potential risk. Limited data are available for breastfeeding; the decision to continue therapy should be made by the prescriber in consultation with the patient.

To place an order, submit an enquiry on the Lanoxin product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Lanoxin belongs to the cardiac glycoside class, offering positive inotropic effects and rate control, which differs from beta‑blockers, ACE inhibitors, or diuretics that primarily reduce workload or fluid overload. While digoxin can be useful in selected patients, especially those with concomitant atrial fibrillation, its narrow therapeutic window requires careful monitoring compared with many newer agents.

Store Lanoxin tablets at ambient temperature, preferably below 25 °C. Keep them in the original container, protect from moisture and direct light, and ensure the packaging remains tightly closed until use. Do not store in the bathroom or near heat sources.

Lanoxin is taken orally, usually as a tablet swallowed whole with a glass of water. It may be taken with or without food, but consistency with meals is recommended to maintain stable absorption. Patients should follow the dosing schedule prescribed by their healthcare provider.

The most critical risks include cardiac arrhythmias such as ventricular tachycardia or fibrillation, severe bradycardia, and life‑threatening hyperkalemia. Early signs of toxicity—nausea, vomiting, visual changes, or confusion—should prompt immediate medical evaluation.

Lanoxin is contraindicated in patients with ventricular fibrillation, known hypersensitivity to digoxin or other cardiac glycosides, and in those with uncontrolled atrial or ventricular tachyarrhythmias. Caution is also advised for individuals with severe renal impairment, electrolyte disturbances, or those taking interacting medications that markedly raise digoxin levels.