Product image of Lanreotid Amdipharm (Lanreotide Acetate) supplied by GNH India

Lanreotid Amdipharm

Active Ingredient:
Lanreotide Acetate
Origin:
EU

Lanreotid Amdipharm (Lanreotide Acetate)

Lanreotide acetate, the active ingredient in Lanreotid Amdipharm, is a somatostatin analog presented as a subcutaneous formulation for injection use. It mimics natural somatostatin to suppress excess hormone secretion and is employed to manage hormone‑related disorders such as acromegaly and certain neuroendocrine tumors in adult patients.

GNH India supplies Lanreotid Amdipharm as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, oncology centres, specialty clinics and pharmacies worldwide, backed by established cold‑chain logistics and regulatory expertise and ensures timely delivery to global markets.

Manufacturer / TM Owner

Amdipharm Limited

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Indications & Clinical Uses

Lanreotide acetate is used in endocrine disorders that involve excess hormone secretion.

  • Acromegaly: reduces excess growth hormone and IGF‑1 levels, helping control disease activity.
  • Gastroenteropancreatic neuroendocrine tumors (GEP‑NETs): inhibits tumor growth and hormone secretion.
  • Carcinoid syndrome associated with NETs: alleviates flushing and diarrhea by suppressing serotonin release.

How It Works

  • Lanreotide acetate is a synthetic somatostatin analogue that binds with high affinity to somatostatin receptor subtypes SSTR2 and SSTR5. Receptor activation inhibits adenylate cyclase activity, reduces calcium influx, and suppresses the release of growth hormone, insulin‑like growth factor‑1, and various gastrointestinal hormones, thereby controlling hormone‑driven disease processes.

Side Effects

Common Side Effects

  • Injection site pain or erythema
  • Diarrhea or loose stools
  • Nausea or abdominal discomfort
  • Headache
  • Constipation
  • Fatigue

Serious or Rare Side Effects

  • Gallbladder disease or biliary sludge
  • Hyperglycemia or new‑onset diabetes
  • Acute pancreatitis
  • Severe allergic reactions (anaphylaxis)
  • Injection site necrosis or infection
  • Cardiovascular events such as arrhythmia

Precautions & Warnings

Lanreotide acetate requires careful monitoring and patient counseling.

  • Glucose monitoring: assess blood sugar levels regularly, especially in diabetic patients.
  • Gallbladder assessment: evaluate for gallstones or biliary symptoms before and during therapy.
  • Hypersensitivity: discontinue if signs of allergic reaction appear.
  • Hepatic or renal impairment: adjust therapy based on clinical judgment.
  • Pregnancy and lactation: use only if the potential benefit justifies the potential risk.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Lanreotide acetate may interact with several drug classes.

Major Interactions (Avoid)

  • Concomitant use with other somatostatin analogues: increased risk of gallbladder complications.
  • Cyclosporine: may enhance cyclosporine levels, requiring dose adjustment.

Moderate Interactions (Monitor Closely)

  • Oral glucose‑lowering agents: may require dose modification due to altered glucose metabolism.
  • Antidiabetic insulin: monitor for hypoglycemia.
  • Medications affecting gastrointestinal motility: potential additive effects on absorption.

Frequently Asked Questions

Lanreotid Amdipharm, containing lanreotide acetate, is indicated for the treatment of acromegaly and for managing gastroenteropancreatic neuroendocrine tumors, including symptom control of carcinoid syndrome associated with these tumors.

Lanreotide acetate is a synthetic analogue of somatostatin. It binds to somatostatin receptors, especially SSTR2 and SSTR5, inhibiting the secretion of growth hormone, IGF‑1, and various gastrointestinal hormones, which helps control hormone‑driven disease activity.

The specific dose and dosing interval of Lanreotid Amdipharm are determined by the prescribing clinician based on the patient’s condition, disease severity, and response to therapy. Patients should follow the prescriber’s instructions.

Safety data for lanreotide acetate in pregnancy and lactation are limited. The product should only be used if the potential benefit to the mother outweighs any possible risk to the fetus or infant, and this decision must be made by the treating physician.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed), and import documentation.

Lanreotid Amdipharm (lanreotide acetate) is similar to other long‑acting somatostatin analogues such as octreotide LAR. Both suppress hormone secretion, but lanreotide is administered as a deep‑subcutaneous injection and may have a slightly different dosing schedule, which can influence convenience and patient preference.

Lanreotid Amdipharm should be stored at 2‑8 °C (refrigerated). Keep the product in its original packaging, protect it from light, and avoid freezing or shaking the vial to maintain stability.

The medication is given by deep subcutaneous injection, typically in the abdominal wall, thigh, or upper arm. Administration is performed by a healthcare professional or a trained patient following aseptic technique and the prescriber’s instructions.

Serious risks include gallbladder disease (such as gallstones or biliary sludge), hyperglycemia or new‑onset diabetes, acute pancreatitis, and severe allergic reactions. Patients should be monitored for these events and instructed to report any concerning symptoms promptly.

Lanreotid Amdipharm is contraindicated in patients with known hypersensitivity to lanreotide acetate or any of the formulation excipients. Caution is also advised for individuals with severe hepatic impairment, uncontrolled diabetes, or active gallbladder disease.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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