Product image of Lanrod (Lanreotide) supplied by GNH India

Lanrod

Active Ingredient:
Lanreotide
Origin:
EU

Lanrod (Lanreotide)

Lanreotide, the active ingredient in Lanrod, is a somatostatin analog presented as an injectable formulation for subcutaneous use. It is employed in the management of hormone‑related disorders such as acromegaly and certain neuroendocrine tumors, acting to suppress excess peptide hormone secretion in adult patients.
GNH India supplies Lanrod as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, oncology centres, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Pharmathen S.A.

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Indications & Clinical Uses

  • Lanrod is a somatostatin analog used to control hormone‑driven conditions within the endocrine and neuroendocrine disease spectrum.
  • Acromegaly: reduces elevated growth‑hormone levels and associated clinical features.
  • Neuroendocrine tumors: controls tumor‑related hormone secretion and helps stabilize disease progression.

How It Works

  • Lanreotide binds with high affinity to somatostatin receptors subtype 2 (SSTR2) and subtype 5 (SSTR5) on target cells. This interaction inhibits adenylate cyclase activity, reduces cyclic AMP formation, and suppresses the release of growth hormone, insulin, glucagon, and various peptide hormones, thereby modulating endocrine and neuroendocrine signaling pathways.

Side Effects

Lanrod may cause a range of adverse reactions that vary in frequency and severity.

Common Side Effects

  • Injection site pain or erythema.
  • Diarrhea or loose stools.
  • Nausea and abdominal discomfort.
  • Hyperglycemia or altered glucose tolerance.
  • Headache.
  • Fatigue.

Serious or Rare Side Effects

  • Gallstone formation or biliary colic.
  • Acute pancreatitis.
  • Severe hypersensitivity reactions, including anaphylaxis.
  • Cardiac arrhythmias.
  • Severe hyperglycemia requiring medical intervention.
  • Persistent gastrointestinal obstruction.

Precautions & Warnings

Before initiating Lanrod, clinicians should consider several safety measures.

  • Glucose monitoring: assess blood‑sugar levels regularly, especially in diabetic patients.
  • Gallbladder evaluation: perform imaging if a history of gallstones exists.
  • Gastrointestinal assessment: watch for signs of bowel obstruction or severe abdominal pain.
  • Renal/hepatic function: adjust use in patients with significant impairment.
  • Hypersensitivity: discontinue if an allergic reaction occurs.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Lanrod can interact with other medicines, requiring attention to potential additive or antagonistic effects.

Major Interactions (Avoid)

  • Concomitant use with other somatostatin analogs: may cause excessive hormone suppression.
  • Co‑administration with cyclosporine: can increase cyclosporine concentrations.

Moderate Interactions (Monitor Closely)

  • Antidiabetic agents: lanreotide may alter glucose control, requiring dose adjustments.
  • Oral contraceptives: possible reduction in contraceptive efficacy.
  • CYP450 substrates: monitor for altered metabolism of drugs processed by this pathway.
  • Cholesterol‑lowering agents: increased risk of gallstone formation.
  • Anticoagulants: monitor coagulation parameters as hormonal changes may affect clotting.

Frequently Asked Questions

Lanrod, containing the somatostatin analog lanreotide, is prescribed for adults with acromegaly to lower excess growth‑hormone levels and for patients with certain neuroendocrine tumors to control hormone‑related symptoms and disease progression.

Lanreotide binds to somatostatin receptors SSTR2 and SSTR5 on endocrine and neuroendocrine cells. This binding blocks adenylate cyclase, reduces cyclic AMP, and suppresses the secretion of growth hormone, insulin, glucagon, and other peptide hormones, thereby moderating the hormonal excess that drives the targeted diseases.

The specific dose and dosing interval of Lanrod are determined by the prescribing clinician based on the individual patient's condition, disease severity, and response to therapy. Dosage adjustments are made according to clinical guidelines and patient monitoring.

Safety data for lanreotide in pregnancy and lactation are limited. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and the decision must be made by a qualified healthcare professional.

To request Lanrod, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain handling if needed), and necessary import documentation.

Lanrod (lanreotide) and other analogs such as octreotide share a similar mechanism of receptor binding but differ in formulation, dosing frequency, and pharmacokinetic profile. Lanreotide is often administered as a long‑acting injectable, allowing less frequent dosing compared with some short‑acting alternatives.

Lanrod should be stored refrigerated at 2‑8 °C, protected from light, and must not be frozen or shaken. Keep the product in its original packaging until use to maintain stability and potency.

Lanrod is given by subcutaneous injection, typically into the abdominal wall or thigh. The injection is performed by a healthcare professional or a trained patient following aseptic technique and the specific administration instructions provided by the prescriber.

Serious risks include gallstone formation, acute pancreatitis, severe hypersensitivity reactions such as anaphylaxis, and marked hyperglycemia that may require medical intervention. Patients should be monitored closely for these events, especially during the initial treatment period.

Lanrod is contraindicated in individuals with known hypersensitivity to lanreotide or any of the formulation excipients. Caution is also advised for patients with severe uncontrolled diabetes, active gallbladder disease, or those who are pregnant or breastfeeding unless clearly indicated by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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