Product image of Lansobene (Lansoprazole) supplied by GNH India

Lansobene

Active Ingredient:
Lansoprazole
Origin:
EU

Lansobene (Lansoprazole)

Lansoprazole, the active ingredient in Lansobene, is a proton pump inhibitor presented as an oral tablet for oral use. It reduces gastric acid secretion and is used to manage acid‑related disorders such as gastro‑oesophageal reflux disease and peptic ulcer disease in adult patients.
GNH India supplies Lansobene as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Teva B.V

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Indications & Clinical Uses

Lansobene, a proton pump inhibitor, is employed to treat conditions caused by excess gastric acid.

  • Gastro‑oesophageal reflux disease (GERD): lowers acid exposure and promotes healing of the oesophageal lining.
  • Peptic ulcer disease: facilitates ulcer healing and prevents recurrence.
  • Helicobacter pylori eradication regimens: enhances the effectiveness of combination antibiotic therapy.
  • Erosive oesophagitis: reduces inflammation and promotes mucosal repair.

How It Works

  • Lansoprazole irreversibly binds to the H+/K+ ATPase enzyme (gastric proton pump) located on the secretory surface of parietal cells in the stomach. By inhibiting this final step of acid production, it markedly decreases both basal and stimulated gastric acid secretion, thereby increasing gastric pH and allowing healing of acid‑related mucosal damage.

Side Effects

Adverse reactions may occur with Lansobene use.

Common Side Effects

  • Headache: mild to moderate intensity.
  • Diarrhoea: loose stools occurring intermittently.
  • Nausea: feeling of stomach upset.
  • Abdominal pain: discomfort in the upper abdomen.

Serious or Rare Side Effects

  • Acute interstitial nephritis: signs of kidney inflammation.
  • Severe allergic reactions: rash, swelling, or difficulty breathing.
  • Clostridioides difficile infection: persistent diarrhoea with fever.

Precautions & Warnings

Before prescribing Lansobene, consider the following precautions.

  • Assess renal function: adjust use in severe impairment.
  • Evaluate hepatic status: monitor in patients with liver disease.
  • Review concomitant medications: potential for reduced efficacy of drugs requiring acidic pH.
  • Long‑term use: monitor for vitamin B12 deficiency and bone density loss.
  • Pregnancy and lactation: weigh benefits against potential risks.

Store at ambient temperature: keep in original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Lansobene may interact with several medicines.

Major Interactions (Avoid)

  • Clopidogrel: reduced antiplatelet effect.
  • Atazanavir: decreased antiviral absorption.
  • Methotrexate (high dose): increased toxicity.

Moderate Interactions (Monitor Closely)

  • Warfarin: possible alteration of INR.
  • Digoxin: modest increase in serum levels.
  • Iron salts: reduced iron absorption when taken concurrently.

Frequently Asked Questions

Lansobene, containing lansoprazole, is indicated for the management of gastro‑oesophageal reflux disease, peptic ulcer disease, Helicobacter pylori eradication regimens, and erosive oesophagitis. It works by reducing gastric acid production, helping to heal and prevent damage to the gastrointestinal lining.

Lansoprazole selectively and irreversibly inhibits the H+/K+ ATPase enzyme, also known as the gastric proton pump, on the secretory surface of stomach parietal cells. This blockade stops the final step of acid secretion, leading to a sustained increase in gastric pH and allowing ulcerated or inflamed tissue to recover.

The appropriate dose of Lansobene is determined by the prescribing healthcare professional based on the specific indication, patient age, renal and hepatic function, and other clinical factors. Patients should follow the dosage instructions provided by their prescriber and not adjust the dose on their own.

Safety of Lansobene in pregnancy or lactation has not been fully established. The prescriber should evaluate the potential benefits against any possible risks to the fetus or infant. If treatment is necessary, it should be used only under medical supervision.

To request Lansobene, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, and will verify trade or institutional credentials before providing pricing, availability, shipping details and any required import documentation.

Lansobene (lansoprazole) belongs to the same class as omeprazole, esomeprazole and pantoprazole. All share a similar mechanism of irreversible proton pump inhibition, but differences exist in pharmacokinetic profiles, drug‑interaction potential and dosing frequency. Choice of agent often depends on physician preference, patient response and specific drug‑interaction considerations.

Lansobene should be stored at ambient temperature, below 25 °C, in its original packaging. Protect the tablets from moisture, excessive heat and direct sunlight to maintain product stability throughout its shelf life.

Lansobene is taken orally, usually as a whole tablet swallowed with a glass of water. It is generally recommended to take the medication before a meal, unless the prescriber provides alternative instructions based on the individual treatment plan.

Serious but rare adverse events linked to Lansobene include acute interstitial nephritis, severe allergic reactions such as anaphylaxis, and Clostridioides difficile‑associated diarrhoea. Patients should seek immediate medical attention if they experience symptoms like rash, swelling, breathing difficulty, or persistent watery stools.

Lansobene is contraindicated in patients with known hypersensitivity to lansoprazole or any component of the formulation. Caution is also advised for individuals with severe liver disease, those taking medications that require an acidic gastric environment for absorption, and patients with a history of allergic reactions to other proton pump inhibitors.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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