Product image of Lansoprazol Ab (Lansoprazole) supplied by GNH India

Lansoprazol Ab

Active Ingredient:
Lansoprazole
Origin:
EU

Lansoprazol Ab (Lansoprazole)

Lansoprazole, the active ingredient in Lansoprazol Ab, is a proton pump inhibitor presented as an oral dosage form for oral use. It reduces gastric acid secretion and is employed in the management of gastro‑oesophageal reflux disease, peptic ulcer disease, erosive oesophagitis and as part of Helicobacter pylori eradication regimens.

GNH India supplies Lansoprazol Ab as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Aurobindo N.V.

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Indications & Clinical Uses

Lansoprazole is indicated for several acid‑related conditions, acting on the gastric proton pump to lower acid output.

  • Gastro‑oesophageal reflux disease (GERD): alleviates heartburn and esophageal irritation.
  • Peptic ulcer disease: promotes ulcer healing by reducing gastric acidity.
  • Helicobacter pylori eradication: used in combination therapy to increase eradication rates.
  • Erosive oesophagitis: heals mucosal damage caused by acid reflux.

How It Works

  • Lansoprazole selectively and irreversibly inhibits the H+/K+ ATPase enzyme (the gastric proton pump) located on the secretory surface of parietal cells. By blocking this final step of acid production, it markedly reduces both basal and stimulated gastric acid secretion, thereby increasing gastric pH and allowing mucosal healing in acid‑related disorders.

Side Effects

Adverse reactions may occur with lansoprazole use.

Common Side Effects

  • Headache: mild to moderate intensity.
  • Diarrhea: watery stools, usually transient.
  • Nausea: occasional upset stomach.
  • Abdominal pain: cramping or discomfort.
  • Flatulence: increased gas.
  • Constipation: reduced bowel movements.

Serious or Rare Side Effects

  • Severe allergic reaction: rash, swelling, difficulty breathing.
  • Clostridioides difficile infection: persistent diarrhea, abdominal pain.
  • Low magnesium levels: muscle cramps, irregular heartbeat.
  • Bone fractures: increased risk with long‑term use.
  • Liver enzyme elevation: abnormal liver function tests.
  • Acute interstitial nephritis: kidney inflammation presenting with fever and rash.

Precautions & Warnings

Before prescribing lansoprazole, consider the following precautions.

  • Assess renal function: adjust use in severe impairment.
  • Evaluate hepatic status: use with caution in liver disease.
  • Review long‑term therapy: monitor for bone density loss.
  • Monitor electrolytes: especially magnesium during prolonged treatment.
  • Consider infection risk: prolonged acid suppression may increase gastrointestinal infections.
  • Store at ambient temperature: keep below 25 °C, in the original container, protected from moisture and light.

Avoid Interactions

Lansoprazole may interact with several medicines; awareness of interaction severity guides management.

Major Interactions (Avoid)

  • Clopidogrel: reduced antiplatelet effect; consider alternative therapy.
  • Atazanavir: decreased absorption; avoid co‑administration.
  • Methotrexate (high dose): increased toxicity risk.

Moderate Interactions (Monitor Closely)

  • Warfarin: potential increase in INR; monitor coagulation.
  • Digoxin: altered serum levels; check concentrations.
  • Diazepam: increased plasma concentration; observe for sedation.
  • Ketoconazole/Itraconazole: reduced antifungal efficacy; consider dosage adjustment.

Frequently Asked Questions

Lansoprazol Ab contains lansoprazole, a proton pump inhibitor used to treat acid‑related conditions such as gastro‑oesophageal reflux disease, peptic ulcer disease, erosive oesophagitis, and as part of combination therapy for Helicobacter pylori eradication.

Lansoprazole blocks the H+/K+ ATPase enzyme, also known as the gastric proton pump, on parietal cells. This inhibition stops the final step of acid production, leading to a sustained reduction in gastric acidity and allowing damaged mucosa to heal.

The appropriate dose of Lansoprazol Ab is determined by the prescribing healthcare professional based on the specific indication, patient age, renal and hepatic function, and treatment duration. Patients should follow the prescriber’s instructions exactly.

Safety data for lansoprazole in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any potential risk to the fetus or infant, and the decision should be made by a qualified healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Lansoprazole is comparable to other PPIs such as omeprazole and esomeprazole in efficacy for acid suppression. Differences may include dosing frequency, drug‑interaction profiles, and individual patient response. Choice of PPI often depends on physician preference, patient tolerance and specific clinical circumstances.

Lansoprazol Ab should be stored at ambient temperature, below 25 °C, in its original packaging to protect it from moisture and light. Keep the product out of reach of children and do not use after the expiry date.

Lansoprazol Ab is taken orally, usually as a whole tablet swallowed with water. It is generally recommended to take the medication before a meal, but patients should follow the specific instructions provided by their prescriber.

Serious adverse events, though rare, include severe allergic reactions (anaphylaxis), Clostridioides difficile‑associated diarrhea, low magnesium levels, acute interstitial nephritis, and increased risk of bone fractures with long‑term use. Patients should seek medical attention if they experience any of these symptoms.

Lansoprazol Ab is contraindicated in individuals with known hypersensitivity to lansoprazole or other proton pump inhibitors. Caution is advised for patients with severe liver disease, those taking medications that have major interactions, and patients with a history of certain infections or bone disorders.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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