Product image of Lansoprazol Alter (Lansoprazole) supplied by GNH India

Lansoprazol Alter

Active Ingredient:
Lansoprazole
Origin:
EU

Lansoprazol Alter (Lansoprazole)

Lansoprazole, the active ingredient in Lansoprazol Alter, is a proton pump inhibitor presented as an oral dosage form for oral use. It reduces gastric acid production and is used to treat conditions such as gastro‑oesophageal reflux disease, peptic ulcer disease and to aid Helicobacter pylori eradication regimens.

GNH India supplies Lansoprazol Alter as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies, transplant centres and oncology clinics worldwide, ensuring quality and regulatory compliance across global markets with reliable logistics and support.

Manufacturer / TM Owner

Alter S.A.

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Indications & Clinical Uses

Lansoprazole is a proton pump inhibitor used to manage acid‑related gastrointestinal disorders.

  • Gastro‑oesophageal reflux disease (GERD): reduces acid exposure, relieving symptoms and healing esophageal damage.
  • Peptic ulcer disease: promotes ulcer healing and helps prevent recurrence.
  • Helicobacter pylori eradication: used as part of combination therapy to increase eradication rates.

How It Works

  • Lansoprazole selectively and irreversibly inhibits the H+/K+ ATPase enzyme (the gastric proton pump) located on the secretory surface of parietal cells in the stomach. By blocking this final step of acid secretion, it markedly reduces both basal and stimulated gastric acid output, leading to an increase in gastric pH. The inhibition persists until new enzyme molecules are synthesized, providing prolonged acid suppression over 24 hours after a single dose.

Side Effects

Lansoprazole may be associated with a range of adverse reactions, varying from mild to serious.

Common Side Effects

  • Headache: mild to moderate headache reported.
  • Diarrhea: loose stools or increased frequency.
  • Nausea: feeling of sickness or urge to vomit.
  • Abdominal pain: discomfort or cramping in the stomach area.
  • Flatulence: increased gas production.
  • Constipation: reduced bowel movements.

Serious or Rare Side Effects

  • Anaphylaxis: severe allergic reaction with rash, swelling, breathing difficulty.
  • Stevens‑Johnson syndrome: rare skin disorder with blistering and detachment.
  • Clostridioides difficile infection: severe colitis presenting with watery diarrhea.
  • Hypomagnesemia: low blood magnesium causing muscle cramps or arrhythmia.
  • Bone fracture: increased risk of hip or wrist fractures with long‑term use.
  • Elevated liver enzymes: signs of liver injury indicated by lab tests.

Precautions & Warnings

When prescribing lansoprazole, several safety considerations should be reviewed to minimize risk.

  • Assess renal function: adjust use in severe renal impairment.
  • Monitor magnesium levels: prolonged therapy may cause hypomagnesemia.
  • Avoid concomitant use with certain antiretrovirals: may reduce efficacy of those agents.
  • Use with caution in patients with hepatic disease: dose may need adjustment.
  • Discontinue before elective surgery: to reduce risk of postoperative complications.
  • Store at room temperature: keep in original container, protect from moisture and light.

Avoid Interactions

Lansoprazole can affect the pharmacokinetics of several medicines; interactions range from major to moderate.

Major Interactions (Avoid)

  • Clopidogrel: reduced antiplatelet effect.
  • Atazanavir: decreased absorption of atazanavir.
  • Methotrexate: increased toxicity.
  • Warfarin: may increase INR.
  • Ketoconazole: reduced azole absorption.

Moderate Interactions (Monitor Closely)

  • Digoxin: may increase serum levels.
  • Phenytoin: may reduce phenytoin levels.
  • Diazepam: may increase sedation.
  • Iron supplements: decrease lansoprazole absorption.
  • Vitamin B12: long‑term use may impair absorption.

Frequently Asked Questions

Lansoprazol Alter contains lansoprazole, a proton pump inhibitor indicated for the treatment of gastro‑oesophageal reflux disease, peptic ulcer disease and as part of combination therapy for Helicobacter pylori eradication. It works by reducing gastric acid secretion, helping to relieve symptoms and promote healing.

Lansoprazole selectively and irreversibly blocks the H+/K+ ATPase enzyme, also known as the gastric proton pump, on the surface of stomach parietal cells. By inhibiting this final step of acid production, it markedly lowers both basal and stimulated gastric acid output, raising the gastric pH.

The appropriate dose of Lansoprazol Alter is determined by a qualified prescriber based on the patient’s specific condition, severity, and clinical response. Dosage may vary for different indications and patient populations, and the prescribing information provides guidance for safe and effective use.

Safety data for lansoprazole in pregnancy and lactation are limited. The prescriber should weigh potential benefits against possible risks to the fetus or infant. If treatment is considered essential, it may be used under close medical supervision, but alternative therapies are preferred when possible.

To request Lansoprazol Alter, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will verify trade or institutional credentials before providing pricing, availability, shipping details and any necessary import documentation.

Lansoprazol Alter belongs to the proton pump inhibitor class, which provides more potent and longer‑lasting acid suppression than H2‑receptor antagonists such as ranitidine. Compared with other PPIs, its efficacy and safety profile are similar, though individual patient response and drug‑interaction potential may differ.

Lansoprazol Alter should be stored at room temperature, preferably below 25 °C, in its original packaging. Protect the product from moisture, direct sunlight and excessive heat to maintain its stability and potency throughout its shelf life.

Lansoprazol Alter is taken orally, usually as a tablet or capsule, with a glass of water. It is commonly administered before a meal, often in the morning, but the exact timing and frequency should follow the prescribing clinician’s instructions.

Serious risks, though rare, include severe allergic reactions such as anaphylaxis, skin disorders like Stevens‑Johnson syndrome, Clostridioides difficile‑associated colitis, low magnesium levels (hypomagnesemia), and increased risk of bone fractures with long‑term use. Patients should seek immediate medical attention if any of these occur.

Lansoprazol Alter is contraindicated in patients with known hypersensitivity to lansoprazole or any component of the formulation. Caution is advised for individuals with severe liver disease, certain drug interactions, or those who have experienced serious adverse reactions to other proton pump inhibitors.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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