Product image of Lansoprazol Aurobindo (Lansoprazole) supplied by GNH India

Lansoprazol Aurobindo

Active Ingredient:
Lansoprazole
Origin:
EU

Lansoprazol Aurobindo (Lansoprazole)

Lansoprazole, the active ingredient in Lansoprazol Aurobindo, is a proton pump inhibitor presented as an oral tablet for systemic use. It reduces gastric acid production and is employed in the management of acid‑related gastrointestinal conditions in adults. The medication is formulated for oral administration and is indicated for conditions where suppression of gastric acidity is required.

GNH India supplies Lansoprazol Aurobindo as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Puren Pharma Gmbh & Co. Kg

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Indications & Clinical Uses

Lansoprazole is a proton pump inhibitor used to treat disorders related to excess stomach acid.

  • Gastro‑esophageal reflux disease (GERD): reduces reflux symptoms and promotes healing of esophageal irritation.
  • Peptic ulcer disease: facilitates ulcer healing by lowering gastric acidity.
  • Helicobacter pylori eradication regimens: enhances the effectiveness of antibiotic combinations.
  • Prevention of NSAID‑induced gastric ulcers: protects the gastric mucosa in patients receiving non‑steroidal anti‑inflammatory drugs.

How It Works

  • Lansoprazole irreversibly binds to the H+/K+ ATPase enzyme (gastric proton pump) located on the secretory surface of parietal cells. By inhibiting this final step of acid secretion, it markedly reduces both basal and stimulated gastric acid output, leading to an increase in gastric pH and providing a therapeutic environment for ulcer healing and symptom relief.

Side Effects

Lansoprazole may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Headache: mild to moderate intensity.
  • Diarrhea: loose stools occurring intermittently.
  • Nausea: occasional feeling of queasiness.
  • Abdominal pain: discomfort in the stomach region.
  • Flatulence: increased intestinal gas.
  • Constipation: reduced bowel movements.

Serious or Rare Side Effects

  • Severe allergic reaction (anaphylaxis): rash, swelling, difficulty breathing.
  • Clostridium difficile infection: severe diarrhea with abdominal cramping.
  • Low magnesium levels (hypomagnesemia): muscle weakness, irregular heartbeat.
  • Elevated liver enzymes: possible hepatitis.
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis: severe skin reactions.
  • Interstitial nephritis: kidney inflammation presenting with fever and rash.

Precautions & Warnings

When prescribing lansoprazole, clinicians should consider several safety precautions.

  • Renal or hepatic impairment: assess function before initiating therapy.
  • Elderly patients: start with the lowest effective dose and monitor response.
  • Magnesium deficiency: monitor serum magnesium during prolonged use.
  • Rebound acid hypersecretion: avoid abrupt discontinuation after long‑term therapy.
  • Concomitant medications affecting gastric pH: review for potential interactions.
  • Store at room temperature: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Lansoprazole can affect the pharmacokinetics of other medicines.

Major Interactions (Avoid)

  • Atazanavir: reduced absorption leading to therapeutic failure.
  • Nelfinavir: decreased plasma concentrations.
  • Rilpivirine: lowered exposure compromising antiviral effect.
  • Clopidogrel: reduced activation, decreasing antiplatelet efficacy.
  • Methotrexate: increased serum levels, raising toxicity risk.

Moderate Interactions (Monitor Closely)

  • Warfarin: possible increase in INR, requiring closer monitoring.
  • Digoxin: modest rise in serum concentration.
  • Ketoconazole: decreased absorption, may need dose adjustment.
  • Iron salts: reduced iron uptake, separate dosing times.
  • Vitamin B12: long‑term use may impair absorption, monitor levels.

Frequently Asked Questions

Lansoprazol Aurobindo is indicated for the treatment of gastro‑esophageal reflux disease (GERD), peptic ulcer disease, as part of Helicobacter pylori eradication regimens, and for the prevention of gastric ulcers associated with long‑term non‑steroidal anti‑inflammatory drug (NSAID) therapy.

Lansoprazole blocks the H+/K+ ATPase enzyme, also known as the gastric proton pump, on the surface of parietal cells. By irreversibly inhibiting this pump, it suppresses the final step of gastric acid secretion, leading to a sustained increase in gastric pH.

The appropriate dose of Lansoprazol Aurobindo is determined by the prescribing healthcare professional based on the specific indication, severity of disease, patient age, renal and hepatic function, and any concomitant medications.

Safety data for lansoprazole in pregnancy and lactation are limited. The drug should only be used if the potential benefit to the mother outweighs any possible risk to the fetus or infant, and this decision must be made by a qualified healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Lansoprazole and omeprazole belong to the same class of proton pump inhibitors and share a similar mechanism of action. Differences may exist in pharmacokinetic profiles, drug‑interaction potential, and individual patient response, which clinicians consider when selecting therapy.

Store the tablets at room temperature, below 25 °C, in the original container. Protect them from moisture, excessive heat and direct sunlight to maintain product stability.

Lansoprazol Aurobindo is taken orally, usually as a whole tablet with a glass of water. It is generally recommended to swallow the tablet before a meal, but the exact timing should follow the prescriber’s instructions.

Serious adverse events include severe allergic reactions (anaphylaxis), Clostridium difficile‑associated diarrhea, low magnesium levels, liver enzyme elevations, and rare skin disorders such as Stevens‑Johnson syndrome. Patients should seek immediate medical attention if they experience any of these symptoms.

Lansoprazol Aurobindo should be avoided in patients with known hypersensitivity to lansoprazole or other proton pump inhibitors, and in individuals with severe liver disease where the drug’s safety has not been established. Caution is also advised for patients with certain bone metabolism disorders.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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