Product image of Lansoprazol Cinfamed (Lansoprazole) supplied by GNH India

Lansoprazol Cinfamed

Active Ingredient:
Lansoprazole
Origin:
EU

Lansoprazol Cinfamed (Lansoprazole)

Lansoprazole, the active ingredient in Lansoprazol Cinfamed, is a proton pump inhibitor presented as an oral dosage form for oral use. It reduces gastric acid production and is used to treat conditions such as gastro‑oesophageal reflux disease, peptic ulcer disease, Helicobacter pylori eradication regimens, and Zollinger‑Ellison syndrome in adult patients.

GNH India supplies Lansoprazol Cinfamed as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable sourcing for global healthcare providers.

Manufacturer / TM Owner

Laboratorios Cinfa S.A.

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Indications & Clinical Uses

Lansoprazol Cinfamed is a proton pump inhibitor used to manage acid‑related gastrointestinal disorders.

  • Gastro‑oesophageal reflux disease (GERD): Decreases gastric acid, relieving heartburn and esophageal irritation.
  • Peptic ulcer disease: Promotes ulcer healing by reducing acid secretion.
  • Helicobacter pylori eradication regimens: Enhances effectiveness of antibiotic therapy by suppressing gastric acid.
  • Zollinger‑Ellison syndrome: Controls excessive gastric acid production associated with gastrin‑secreting tumors.

How It Works

  • Lansoprazole selectively and irreversibly binds to the cysteine residues of the H+/K+ ATPase enzyme (the gastric proton pump) located on the secretory surface of parietal cells. By inhibiting this final step of acid production, it markedly reduces basal and stimulated gastric acid secretion, leading to increased gastric pH and facilitating mucosal healing. The effect persists for up to 72 hours, allowing once‑daily dosing in most patients.

Side Effects

Lansoprazole may be associated with a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Headache: mild, transient headache.
  • Diarrhea: loose stools, usually self‑limiting.
  • Nausea: feeling of sickness.
  • Abdominal pain: mild discomfort in the stomach area.

Serious or Rare Side Effects

  • Clostridioides difficile infection: severe colitis with watery diarrhea.
  • Acute interstitial nephritis: kidney inflammation presenting with rash and fever.
  • Hypomagnesemia: low serum magnesium causing muscle cramps or arrhythmias.

Precautions & Warnings

Before initiating Lansoprazol Cinfamed, consider the following precautions to ensure safe use.

  • Assess renal function: dose adjustment may be needed in severe impairment.
  • Evaluate for osteoporosis risk: long‑term use may affect calcium absorption.
  • Review concomitant medications: potential for drug‑drug interactions.
  • Monitor for gastrointestinal infections: especially with prolonged therapy.
  • Store at room temperature: keep in the original container, protect from moisture.

Avoid Interactions

Lansoprazole can alter the pharmacokinetics of several medicines; awareness of key interactions is essential.

Major Interactions (Avoid)

  • Clopidogrel: reduced antiplatelet activity.
  • Atazanavir: decreased antiviral absorption.

Moderate Interactions (Monitor Closely)

  • Warfarin: enhanced anticoagulant effect, monitor INR.
  • Digoxin: increased serum levels, monitor for toxicity.
  • Methotrexate: higher exposure, especially with high doses.
  • Phenytoin: reduced seizure control, monitor levels.

Frequently Asked Questions

Lansoprazol Cinfamed contains the proton pump inhibitor lansoprazole and is indicated for the treatment of acid‑related gastrointestinal conditions such as gastro‑oesophageal reflux disease, peptic ulcer disease, Helicobacter pylori eradication regimens, and Zollinger‑Ellison syndrome. It works by reducing gastric acid secretion, which helps relieve symptoms and promotes healing of the gastrointestinal mucosa.

Lansoprazole acts by irreversibly inhibiting the H+/K+ ATPase enzyme, also known as the gastric proton pump, located on the secretory surface of parietal cells. This inhibition blocks the final step of acid production, leading to a sustained reduction in gastric acid output and an increase in gastric pH, which supports symptom relief and mucosal healing.

The appropriate dose of Lansoprazol Cinfamed is determined by the prescribing healthcare professional based on the specific indication, severity of the condition, patient age, renal function, and any concomitant therapies. Dosage recommendations are provided in the product labeling, and the prescriber will tailor the regimen to each individual patient.

Safety data for lansoprazole in pregnancy and lactation are limited. The product is classified as pregnancy category unknown, and the decision to use it during pregnancy or while breastfeeding should be made by a qualified healthcare provider after weighing potential benefits against possible risks to the mother and fetus or infant.

To order Lansoprazol Cinfamed, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams across international markets. After the enquiry, the sales team will request trade or institutional credentials, then provide pricing, availability, shipping details (including any cold‑chain requirements) and assist with import documentation.

Lansoprazol Cinfamed is one of several proton pump inhibitors (PPIs) that share a common mechanism of reducing gastric acid secretion. Compared with other PPIs, lansoprazole has a similar efficacy profile but may differ in pharmacokinetic properties such as onset of action, metabolism pathways, and potential drug‑interaction profiles. Choice of a specific PPI often depends on clinician preference, patient tolerance, and individual drug‑interaction considerations.

Lansoprazol Cinfamed should be stored at room temperature, preferably below 25 °C. Keep the product in its original packaging to protect it from moisture and light. Do not store in areas with excessive heat or humidity, and keep it out of reach of children.

Lansoprazol Cinfamed is administered orally, typically as a tablet or capsule taken with water. The medication is usually taken before a meal, often in the morning, but the exact timing and frequency should follow the prescribing clinician’s instructions. Swallow the dosage form whole; do not crush or chew unless specifically advised.

Serious risks, although rare, include Clostridioides difficile‑associated diarrhea, acute interstitial nephritis, and severe hypomagnesemia, which can lead to muscle cramps, seizures, or cardiac arrhythmias. Patients should be monitored for persistent diarrhea, unexplained rash or fever, and signs of low magnesium, especially during prolonged therapy.

Lansoprazol Cinfamed should be avoided in individuals with known hypersensitivity to lansoprazole or any component of the formulation. Caution is also advised for patients with severe liver disease, those taking medications that require an acidic environment for absorption, and patients with a history of osteoporosis when long‑term use is considered.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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