Product image of Lansoprazol Davur (Lansoprazole) supplied by GNH India

Lansoprazol Davur

Active Ingredient:
Lansoprazole
Origin:
EU

Lansoprazol Davur (Lansoprazole)

Lansoprazole, the active ingredient in Lansoprazol Davur, is a proton pump inhibitor presented as an oral dosage form for oral use. It reduces gastric acid production and is employed in the management of acid‑related disorders such as gastro‑esophageal reflux disease and peptic ulcer disease.

GNH India supplies Lansoprazol Davur as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Teva Pharma S.L.U.,

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Indications & Clinical Uses

Lansoprazole acts on the gastric proton pump to lower acid secretion, making it useful for several acid‑related conditions.

  • Gastro‑esophageal reflux disease (GERD): alleviates heartburn and promotes healing of esophageal irritation.
  • Peptic ulcer disease: supports ulcer healing and reduces recurrence risk.
  • Helicobacter pylori eradication (in combination therapy): enhances the effectiveness of antibiotic regimens.
  • Zollinger‑Ellison syndrome: controls excessive gastric acid production.

How It Works

  • Lansoprazole irreversibly binds to the H+/K+ ATPase enzyme (gastric proton pump) located on the secretory surface of parietal cells. By inhibiting this final step of acid secretion, it markedly reduces both basal and stimulated gastric acid output, leading to an increased gastric pH and facilitating mucosal healing in acid‑related disorders.

Side Effects

Lansoprazole is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Headache: mild to moderate intensity.
  • Diarrhea: loose stools, often transient.
  • Nausea: occasional feeling of queasiness.
  • Abdominal pain: discomfort in the stomach area.
  • Flatulence: increased gas production.
  • Constipation: reduced bowel movements.

Serious or Rare Side Effects

  • Severe allergic reactions (anaphylaxis): rash, swelling, difficulty breathing.
  • Clostridioides difficile infection: severe diarrhea with abdominal pain.
  • Elevated liver enzymes: signs of hepatic stress.
  • Hypomagnesemia: low magnesium levels causing muscle cramps.
  • Stevens‑Johnson syndrome: serious skin and mucous membrane disorder.
  • Interstitial nephritis: kidney inflammation presenting with fever and rash.

Precautions & Warnings

Before initiating therapy, consider the following safety measures.

  • Assess renal function: adjust use in patients with severe renal impairment.
  • Monitor for infection: prolonged therapy may increase risk of gastrointestinal infections.
  • Avoid in known hypersensitivity: discontinue if allergic reaction occurs.
  • Use cautiously in elderly: higher incidence of fractures and bone loss.
  • Store at room temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Lansoprazole may affect the pharmacokinetics of several concomitant medicines.

Major Interactions (Avoid)

  • Ketoconazole: reduced absorption and efficacy of ketoconazole.
  • Clopidogrel: decreased antiplatelet effect, increasing cardiovascular risk.
  • Atazanavir: markedly decreased atazanavir exposure.

Moderate Interactions (Monitor Closely)

  • Warfarin: potential increase in INR, requiring closer monitoring.
  • Digoxin: possible rise in serum digoxin levels.
  • Methotrexate: may increase methotrexate toxicity, especially at high doses.

Frequently Asked Questions

Lansoprazol Davur contains lansoprazole, a proton pump inhibitor indicated for the treatment of gastro‑esophageal reflux disease, peptic ulcer disease, Helicobacter pylori eradication when used with antibiotics, and Zollinger‑Ellison syndrome, all of which involve excess gastric acid production.

Lansoprazole irreversibly inhibits the H+/K+ ATPase enzyme, also known as the gastric proton pump, on the surface of parietal cells. This blockade prevents the final step of acid secretion, leading to a sustained increase in gastric pH and allowing damaged mucosa to heal.

The specific dose and dosing schedule of Lansoprazol Davur are determined by the prescribing healthcare professional based on the patient’s condition, severity, and response to therapy. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety data for lansoprazole in pregnancy and lactation are limited. The prescriber will weigh potential benefits against possible risks before recommending use in pregnant or nursing women. Patients should discuss their individual situation with a qualified healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Lansoprazol Davur belongs to the proton pump inhibitor class, which provides more potent and longer‑lasting acid suppression than H2‑receptor antagonists such as ranitidine. Compared with other PPIs, its efficacy and safety profile are similar, though individual response may vary.

Lansoprazol Davur should be stored at room temperature, below 25 °C, in its original packaging. Protect the product from moisture, excessive heat and direct sunlight to maintain its stability and potency.

Lansoprazol Davur is taken orally, usually as a whole tablet or capsule, with a glass of water. It can be taken with or without food, but consistency in relation to meals helps maintain predictable absorption.

Serious risks, though uncommon, include severe allergic reactions such as anaphylaxis, Clostridioides difficile‑associated diarrhea, low magnesium levels, liver enzyme elevations, and rare skin conditions like Stevens‑Johnson syndrome. Patients should seek immediate medical attention if they experience any of these symptoms.

Individuals with known hypersensitivity to lansoprazole or any component of the formulation should avoid the product. Caution is also advised for patients with severe liver disease, those on certain interacting medications, and patients who have experienced previous adverse reactions to proton pump inhibitors.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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