Product image of Lansoprazol Davur (Lansoprazole) supplied by GNH India

Lansoprazol Davur

Active Ingredient:
Lansoprazole
Origin:
EU

Lansoprazol Davur (Lansoprazole)

Lansoprazole, the active ingredient in Lansoprazol Davur, is a proton pump inhibitor presented as an oral dosage form for oral use. It reduces gastric acid secretion and is employed in the management of acid‑related gastrointestinal disorders in adults and adolescents.
GNH India supplies Lansoprazol Davur as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Teva Pharma S.L.U.,

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Indications & Clinical Uses

Lansoprazol Davur is a proton pump inhibitor used to treat conditions caused by excess gastric acid.

  • Gastro‑esophageal reflux disease (GERD): relieves heartburn and promotes healing of esophageal erosion.
  • Peptic ulcer disease: facilitates ulcer healing and reduces recurrence.
  • Helicobacter pylori eradication (in combination therapy): enhances eradication rates when used with antibiotics.
  • Zollinger‑Ellison syndrome: controls hyper‑secretion of gastric acid in this rare endocrine disorder.

How It Works

  • Lansoprazole selectively and irreversibly binds to the H+/K+ ATPase enzyme (gastric proton pump) located on the secretory surface of parietal cells. By inhibiting this final step of acid production, it markedly reduces both basal and stimulated gastric acid secretion, leading to an increased gastric pH and allowing damaged mucosa to heal.

Side Effects

Adverse reactions may occur with lansoprazole therapy.

Common Side Effects

  • Headache: mild to moderate intensity.
  • Diarrhea: watery stools, usually transient.
  • Abdominal pain: discomfort or cramping in the stomach area.
  • Nausea: feeling of queasiness, sometimes with vomiting.
  • Flatulence: increased intestinal gas.
  • Constipation: reduced bowel movements.

Serious or Rare Side Effects

  • Clostridioides difficile infection: severe colitis presenting with watery diarrhea.
  • Severe allergic reactions: rash, swelling, or anaphylaxis.
  • Elevated liver enzymes: signs of hepatic injury.
  • Stevens‑Johnson syndrome: rare skin blistering disorder.
  • Interstitial nephritis: inflammation of kidney tissue.
  • Severe hypomagnesemia: low magnesium levels causing muscle cramps or arrhythmias.

Precautions & Warnings

Before initiating therapy, consider the following safety measures.

  • Assess renal function: use with caution in severe renal impairment.
  • Monitor for infection: prolonged use may increase risk of gastrointestinal infections.
  • Avoid in known hypersensitivity: discontinue if allergic reaction occurs.
  • Use caution in elderly: higher incidence of adverse events.
  • Store at ambient temperature: keep in the original pack, protect from moisture and light.

Avoid Interactions

Lansoprazole may interact with several medicines; review patient medication lists.

Major Interactions (Avoid)

  • Clopidogrel: reduced antiplatelet effect.
  • Atazanavir: decreased absorption of atazanavir.
  • Methotrexate: increased toxicity risk.
  • Warfarin: possible enhancement of anticoagulant effect.

Moderate Interactions (Monitor Closely)

  • Digoxin: may increase serum digoxin levels.
  • Phenytoin: may reduce phenytoin concentrations.
  • Diazepam: may raise diazepam levels.

Frequently Asked Questions

Lansoprazol Davur, containing the proton pump inhibitor lansoprazole, is used to manage acid‑related gastrointestinal disorders such as gastro‑esophageal reflux disease, peptic ulcer disease, Helicobacter pylori eradication regimens, and Zollinger‑Ellison syndrome. By lowering stomach acidity, it helps relieve symptoms and promotes healing of the gastrointestinal lining.

Lansoprazole works by binding irreversibly to the H+/K+ ATPase enzyme, also known as the gastric proton pump, on the secretory surface of parietal cells. This inhibition blocks the final step of gastric acid production, leading to a sustained reduction in both basal and stimulated acid secretion, which raises gastric pH and allows mucosal repair.

The appropriate dose of Lansoprazol Davur is determined by the prescribing healthcare professional based on the specific indication, patient age, renal function, and response to therapy. Patients should follow the prescriber’s instructions and not adjust the dose without medical advice.

Safety data for lansoprazole in pregnancy and lactation are limited. The drug should only be used if the potential benefit justifies any potential risk to the fetus or infant. Healthcare providers will evaluate the individual situation before prescribing it to pregnant or nursing mothers.

To order Lansoprazol Davur, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, and will request trade or institutional credentials. The sales team will then provide pricing, availability, shipping details (including any required temperature control), and assist with import documentation.

Lansoprazol Davur belongs to the proton pump inhibitor class, which generally provides more potent and longer‑lasting acid suppression than H2‑receptor antagonists such as ranitidine. Compared with other PPIs, lansoprazole has a similar efficacy profile but may differ in pharmacokinetic properties, drug‑interaction potential, and individual tolerability.

Lansoprazol Davur should be stored at ambient temperature, below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain stability.

Lansoprazol Davur is taken orally, usually as a whole tablet or capsule, with a glass of water. It is generally recommended to take the dose before a meal, often in the morning, unless the prescriber advises otherwise.

Serious risks, though uncommon, include Clostridioides difficile‑associated diarrhea, severe allergic reactions such as anaphylaxis, liver enzyme elevations, Stevens‑Johnson syndrome, interstitial nephritis, and profound hypomagnesemia. Patients should seek immediate medical attention if they experience symptoms like persistent diarrhea, rash, swelling, jaundice, or muscle cramps.

Individuals with known hypersensitivity to lansoprazole or any component of the formulation should avoid using Lansoprazol Davur. Caution is also advised for patients with severe hepatic impairment, those taking medications that have major interactions, and patients with a history of certain infections or kidney disease, pending medical evaluation.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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